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RCVRN encodes a member of the recoverin family of neuronal calcium sensors. Additionally we are shipping Recoverin Antibodies (134) and Recoverin Kits (1) and many more products for this protein.
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Human Recoverin Protein expressed in Escherichia coli (E. coli) - ABIN666850
Sampath, Weaver, Sungarian, Cortez, Alderson, Stopa: Cerebrospinal fluid (vascular endothelial growth factor) and serologic (recoverin) tumor markers for malignant glioma. in Cancer control : journal of the Moffitt Cancer Center 2004
Show all 2 references for ABIN666850
Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF Hands.
Aberrant hypomethylation of the recoverin gene region, overlapping the promoter up-stream of the first exon and the first exon itself, is involved in the aberrant expression of recoverin in tumor cells.
recoverin has a pathological role in cancer-associated retinopathy
There are cis (show CISH Proteins)-acting elements in the 5' non-coding region of the recoverin gene that are involved in the activation and suppression of gene expression.
Human recoverin is expressed in SCLC cells cultured from an anti-recoverin antibody-negative patient with CAR. KK0206 might be important for further research on SCLC related retinopathy.
A GRK1 (show GRK1 Proteins) region close to its C-terminus also seemed to be the binding site for S-modulin/recoverin.
A novel rhodopsin-kinase (show GRK1 Proteins)-binding site within the C-terminal region of recoverin.
(15) N NMR relaxation data suggest that Ca(2 (show CA2 Proteins)+)-free recoverin undergoes millisecond conformational dynamics at particular amide sites throughout the protein.
Ca2 (show CA2 Proteins)+-myristoyl switch in the neuronal calcium sensor requires different functions of Ca2 (show CA2 Proteins)+-binding sites
Recoverin is a zinc-binding protein
Recoverin and rhodopsin kinase (show GRK1 Proteins) have roles in a Ca2 (show CA2 Proteins)+-dependent feedback loop in membrane rafts from rod outer segments
an interaction surface for the recoverin target rhodopsin kinase (show GRK1 Proteins) is constituted upon Ca2 (show CA2 Proteins)+ binding to the non-acylated mutant
Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase (show GRK1 Proteins)
Ca2+/recoverin has a role in regulating rhodopsin mutants associated with retinitis pigmentosa
propose a novel role of the C-terminal segment of recoverin as an internal modulator of Ca(2 (show CA2 Proteins)+) sensitivity
Time-resolved fluorescence shows biexponential fluorescence decay. The slower time constant was affected by Ca2 (show CA2 Proteins)+-induced conformational changes in WT & RecE85Q (disabled EF-hand 2 (show HAND2 Proteins)), & not RecE121Q (EF-hand 3 nonfunctional) with a clamped myristoyl group.
Rods and cones share the same isoforms of recoverin and GRK1 (show GRK1 Proteins), and photoactivation also triggers a calcium decline in cones
recoverin may modulate the decay of light-activated PDE (show TWIST1 Proteins)*, which may be responsible for the quickening of response recovery in background light.
High anti-recoverin antibody levels were achieved in two mouse models, accompanied by significantly reduced scotopic and photopic responses on the electroretinograms.
This is the first demonstration in an intact rod that light accelerates Rh* inactivation and that the Ca(2+)-binding protein (show PVALB Proteins) recoverin may be required for the light-dependent modulation of Rh* lifetime.
recoverin undergoes light-dependent intracellular translocation in mouse rod photoreceptors
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.
, cancer associated retinopathy antigen
, cancer-associated retinopathy protein
, 23 kDa photoreceptor cell-specific protein
, cancer associated retinopathy protein
, guanylate cyclase activator