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Regulator of G-Protein Signaling 2 Proteins (RGS2)

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. Additionally we are shipping RGS2 Antibodies (77) and RGS2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RGS2 19735 O08849
RGS2 84583 Q9JHX0
RGS2 5997 P41220
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Top RGS2 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,520.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,520.83
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,522.67
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,825.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$364.64
Details

RGS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
, ,

Top referenced RGS2 Proteins

  1. Human RGS2 Protein expressed in Escherichia coli (E. coli) - ABIN667395 : Santos de Araujo, Oba, Moriyama: Role of regulator of G-protein signaling 2 (RGS2) in periodontal ligament cells under mechanical stress. in Cell biochemistry and function 2007 (PubMed)
    Show all 2 references for ABIN667395

More Proteins for Regulator of G-Protein Signaling 2 (RGS2) Interaction Partners

Horse (Equine) Regulator of G-Protein Signaling 2 (RGS2) interaction partners

  1. Gonadotropin-dependent up-regulation of RGS2 in equine and bovine preovulatory follicles and regulatory controls involved in RGS2 gene expression in granulosa cells.

Mouse (Murine) Regulator of G-Protein Signaling 2 (RGS2) interaction partners

  1. RGS2 deficiency decreases uterine artery blood flow by increasing myogenic tone at least partly through prolonged G protein activation

  2. Rgs12 (show RGS12 Proteins) has a crucial role in the function of bone-resorbing OCs, particularly in preclinical models of pathological bone loss associated with inflammation-induced bone loss and postmenopausal osteoporosis.

  3. RGS2 deficiency impairs renal function and autoregulation by increasing renal vascular resistance and reducing renal blood flow.

  4. FBXO44 (show FBXO44 Proteins)-mediated degradation of RGS2 protein uniquely depends on a Cul4B (show CUL4B Proteins)/DDB1 (show DDB1 Proteins) complex.

  5. Regulator of G-protein signaling 2 (RGS2) suppresses premature calcium release in mouse eggs.

  6. genetic variations and increased inflammatory cytokines can lead to RGS2 repression, which exacerbates AHR (show AHR Proteins) and airway remodeling in asthma.

  7. RGS2 and RGS4 are new interacting partners that play key roles in G protein coupling to negatively regulate kappa-OmicronR signaling.

  8. RGS2-deficient VSMC exhibit higher rates of proliferation and coordinate plasticity of Ca(2 (show CA2 Proteins)+)-handling mechanisms in response to PDGF (show PDGFA Proteins) stimulation.

  9. Regulator of G protein signaling 2 deficiency accelerates the progression of kidney fibrosis

  10. These findins indicate that urotensin II (show UTS2 Proteins)-induced calcium metabolism results in glomerular mesangial cell contraction and suggest that urotensin receptor activation recruts RGS2 to the plasma membrane.

Human Regulator of G-Protein Signaling 2 (RGS2) interaction partners

  1. The RGS2 (-391, C>G) genetic polymorphism may serve as a biomarker to predict a patient's response to antihypertensive drug therapy

  2. MIR4717 regulates human RGS2 and contributes to the genetic risk towards anxiety-related traits.

  3. FBXO44 (show FBXO44 Proteins)-mediated degradation of RGS2 protein uniquely depends on a Cul4B (show CUL4B Proteins)/DDB1 (show DDB1 Proteins) complex.

  4. RGS2 polymorphisms were found to be associated with anxiety disorders and dimensional as well as intermediate phenotypes of anxiety.

  5. RGS2 localizes to the mitotic spindle in a Nek7 (show NEK7 Proteins)-dependent manner, and along with Nek7 (show NEK7 Proteins) contributes to spindle morphology and mitotic spindle pole integrity.

  6. genetic variations and increased inflammatory cytokines can lead to RGS2 repression, which exacerbates AHR (show AHR Proteins) and airway remodeling in asthma.

  7. Data show that regulator of G protein signaling 2 (RGS2) was stabilized by deubiquitinase monocyte chemotactic protein-induced protein 1 (MCPIP1 (show ZC3H12A Proteins)).

  8. Epigenetic repression of RGS2 by UHRF1 (show UHRF1 Proteins) contributes to bladder cancer progression. UHRF1 (show UHRF1 Proteins) inhibits RGS2 expression by increasing the methylation of CpG nucleotides of the RGS2 promoter.

  9. ACE (show ACE Proteins) and RGS2 genotypes are not associated with the development of hypertension in patients with type 1 diabetes mellitus.

  10. This work highlights the role of RGS2 as a key regulator of LRRK2 (show LRRK2 Proteins) activity, function and neuronal toxicity.

RGS2 Protein Profile

Protein Summary

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.

Gene names and symbols associated with RGS2

  • regulator of G-protein signaling 2, 24kDa (RGS2)
  • regulator of G-protein signaling 2 (rgs2)
  • regulator of G-protein signaling 2 (Rgs2)
  • regulator of G-protein signaling 2, 24kDa (rgs2)
  • Rieger syndrome 2 (RIEG2)
  • ARS protein
  • fa96c08 protein
  • G0S8 protein
  • GOS8 protein
  • RGS2 protein
  • wu:fa96c08 protein
  • wu:fj08f11 protein
  • zgc:91965 protein

Protein level used designations for RGS2

regulator of G-protein signaling 2 , regulator of G-protein signalling 2 , regulator of G-protein signaling protein 2 , regulator of G-protein signalling 2, 24kDa , G0 to G1 switch regulatory 8, 24kD , G0/G1 switch regulatory protein 8 , cell growth-inhibiting gene 31 protein , cell growth-inhibiting protein 31

GENE ID SPECIES
100051067 Equus caballus
436935 Danio rerio
19735 Mus musculus
84583 Rattus norvegicus
495384 Xenopus laevis
378912 Gallus gallus
488584 Canis lupus familiaris
733670 Sus scrofa
513055 Bos taurus
5997 Homo sapiens
6012 Homo sapiens
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