You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Regulatory Factor X 5 (RFX5) Antibodies

A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). Additionally we are shipping RFX5 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RFX5 5993 P48382
RFX5 53970  
RFX5 310659  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-RFX5 Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RFX5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB RFX5 Antibody (Center) (ABIN657925) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the RFX5 antibody detected the RFX5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EMSA, EIA, IP, WB Figure 1. Anti-RFX5 (aa 320 to 494) is shown to detect RFX5 present in Raji B cell 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated GS, WB Anti-RFX5 (aa 320 to 494) is shown to detect RFX5 present in Raji B cell nuclear extract lysates. Detection occurs using a 1:2,500 dilution of antibody followed by 1:5,000 dilution of HRP Goat-a-Rabbit IgG with visualization via ECL. Film exposure approximately 1’. Other detection systems will yield similar results. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated EMSA, EIA, IP, WB   0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Cow Goat Un-conjugated EIA, WB Staining of Daudi lysate using RFX5 antibody at 2 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EMSA, EIA, IP   0.1 mL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EMSA, EIA, IP   0.1 mL Log in to see 6 to 8 Days
$500.50
Details

RFX5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
, , , , , ,
Mouse (Murine) ,
,

Rat (Rattus)
,

Top referenced anti-RFX5 Antibodies

  1. Human Polyclonal RFX5 Primary Antibody for WB - ABIN2780343 : Xu, Farmer, Smith: Peroxisome proliferator-activated receptor gamma interacts with CIITA x RFX5 complex to repress type I collagen gene expression. in The Journal of biological chemistry 2007 (PubMed)

  2. Human Polyclonal RFX5 Primary Antibody for EMSA, EIA - ABIN116534 : Steimle, Durand, Barras, Zufferey, Hadam, Mach, Reith: A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome). in Genes & development 1995 (PubMed)

  3. Human Polyclonal RFX5 Primary Antibody for GS, WB - ABIN106544 : Xu, Sengupta, Seto, Smith: Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression. in The Journal of biological chemistry 2006 (PubMed)

  4. Human Polyclonal RFX5 Primary Antibody for WB - ABIN657925 : Laird, Briggs, Boss, Summers, Garvie: Solution structure of the heterotrimeric complex between the interaction domains of RFX5 and RFXAP from the RFX gene regulatory complex. in Journal of molecular biology 2010 (PubMed)

  5. Dog (Canine) Polyclonal RFX5 Primary Antibody for WB - ABIN2780342 : Nagarajan, Long, Harreman, Corbett, Boss: A hierarchy of nuclear localization signals governs the import of the regulatory factor X complex subunits and MHC class II expression. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)

More Antibodies against RFX5 Interaction Partners

Human Regulatory Factor X 5 (RFX5) interaction partners

  1. Data show arginine methyltransferase PRMT6 (show PRMT6 Antibodies) methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression.

  2. these data have identified as novel pathway whereby SIRT1 (show SIRT1 Antibodies) maintains COL1A2 (show COL1A2 Antibodies) synthesis in SMCs by modulating RFX5 activity.

  3. RFXAP (show RFXAP Antibodies)(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5(N)(2) staple.

  4. interaction at COL1A2 (show COL1A2 Antibodies) start site and transcription repression

  5. The mutation for the fifth Bbare lymphocyte syndrome complementation group was found in RFX5 and was mapped to one of the arginines in a DNA-binding surface of this protein. Its wild-type counterpart restored function.

  6. RFX5 binds to the collagen transcription start site and represses collagen gene expression

  7. The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression.

  8. results demonstrate that RFX1 (show RFX1 Antibodies) and RFX5 differentially interact with class I HDACs underlying the different pathways when repressing collagen synthesis

  9. PPARgamma (show PPARG Antibodies) is within the RFX5.CIITA (show CIITA Antibodies) complex as judged by co-immunoprecipitation and DNA affinity precipitation studies

  10. RFXAP (show RFXAP Antibodies) and RFXB (show RFXANK Antibodies) have roles in relieving autoinhibition of RFX5

Mouse (Murine) Regulatory Factor X 5 (RFX5) interaction partners

  1. TSA (show PRDX2 Antibodies) treatment enhances the association of CIITA (show CIITA Antibodies) with the transcription factor RFX5, which ameliorates the down-regulation of CIITA (show CIITA Antibodies) recruitment to target promoters by HDAC2 (show HDAC2 Antibodies).

RFX5 Antigen Profile

Protein Summary

A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.

Gene names and symbols associated with RFX5

  • regulatory factor X, 5 (influences HLA class II expression) (RFX5) antibody
  • regulatory factor X, 5 (influences HLA class II expression) (Rfx5) antibody

Protein level used designations for RFX5

DNA-binding protein RFX5 , regulatory factor X 5 , DNA-binding protein Rfx5 , regulatory factor X, 5 , regulator factor X 5

GENE ID SPECIES
5993 Homo sapiens
53970 Mus musculus
483197 Canis lupus familiaris
100328902 Oryctolagus cuniculus
310659 Rattus norvegicus
100517711 Sus scrofa
539884 Bos taurus
Selected quality suppliers for anti-RFX5 (RFX5) Antibodies
Did you look for something else?