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Rh Family A Glycoprotein Proteins (RHAG)

The protein encoded by RHAG is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. Additionally we are shipping RHAG Kits (22) and RHAG Antibodies (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RHAG 6005 Q02094
Rat RHAG RHAG 65207 Q7TNK7
RHAG 19743 Q9QUT0
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Top RHAG Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

RHAG Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Rh Family A Glycoprotein (RHAG) Interaction Partners

Human Rh Family A Glycoprotein (RHAG) interaction partners

  1. novel allele in a Brazilian pregnant woman encoding the Rhnull phenotype due to a change in RHAG exon2 c.310C>T, which leads to a premature stop codon (Gln104Stop).

  2. We characterized ammonia and ammonium (NH3/NH4 (+)) transport by the rhesus-associated (Rh) glycoproteins RhAG, Rhbg, and Rhcg expressed in Xenopus oocytes. We used ion-selective microelectrodes and two-electrode voltage clamp to measure changes in intracellular pH, surface pH, and whole cell currents induced by NH3/NH4 (+) and methyl amine/ammonium (MA/MA(+)).

  3. A new Rh null allele (RHAG*01N.13) of the regulator type found in a consanguineous French-speaking quebecers'family.

  4. RhAG, RhBG and RhCG (show RHCG Proteins)-exhibit significant permeability to NH3 and show for the first time that RhBG and RhCG (show RHCG Proteins) can conduct CO2.

  5. Data from differentiating cultured erythroid precursor cells suggest that RhAG knockdown abolishes Rh blood group (show DARC Proteins) expression (RhoD [ras homolog family member D]; ICAM4 (show ICAM4 Proteins) [intercellular adhesion molecule 4 (show ICAM4 Proteins)]; CD47 Rh-related antigen (show CD47 Proteins)) in erythroid cells.

  6. Substitution of GPB (show GYPB Proteins) with Gp.Mur significantly reduced the expression of Rh antigen and RhAG on the Mi.III(+/+) erythrocyte membrane

  7. Results provide new insights into the functional impact of the Phe65Ser mutation in RhAG.

  8. that the 672C>A missense mutation in the RHAG gene could result in Rh(null) of the regulator type, and the single-amino-acid change (Ser to Arg) might be critical for assembly of the Rh antigen complex within the membrane

  9. The results provide new insight into RhAG stomatocytosis mutant F65S as a combined loss-of-function/gain-of-function mutation for methylammonium/methylammonium+ transport

  10. Cell-surface expression of RhD blood group (show DARC Proteins) polypeptide is posttranscriptionally regulated by the RhAG glycoprotein.

Mouse (Murine) Rh Family A Glycoprotein (RHAG) interaction partners

  1. RhAG expression enhanced the ammonium-induced initial alkalinization (related to NH3 influx)& secondary acidification (related to NH4+ influx). Sub-millimolar NH4+ concentrations induced inward currents in voltage-clamped RhAG-expressing cells.

  2. Review. Rhag plays a major role in the NH3 conductance of erythrocytes, but probably not in CO2 transport.

RHAG Protein Profile

Protein Summary

The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.

Gene names and symbols associated with RHAG

  • Rh-associated glycoprotein (RHAG)
  • Rh-associated glycoprotein (Rhag)
  • Rhesus blood group-associated A glycoprotein (Rhag)
  • CD241 protein
  • RH2 protein
  • Rh50 protein
  • Rh50A protein
  • Rh50GP protein
  • SLC42A1 protein

Protein level used designations for RHAG

Rh blood group-associated glycoprotein , Rhesus blood group-associated glycoprotein , ammonium transporter Rh type A , Rhesus associated polypeptide, 50-KD , erythrocyte membrane glycoprotein Rh50 , erythrocyte plasma membrane 50 kDa glycoprotein , rh family type A glycoprotein , rh type A glycoprotein , rhesus blood group family type A glycoprotein , rhesus blood group-associated ammonia channel , Erythrocyte membrane glycoprotein Rh50 , Rh family type A glycoprotein , Rh type A glycoprotein , Rhesus blood group family type A glycoprotein , Rhesus blood group-associated A glycoprotein , glycoprotein 50kD , 50 kD glycoprotein

GENE ID SPECIES
395118 Gallus gallus
6005 Homo sapiens
481833 Canis lupus familiaris
65207 Rattus norvegicus
281454 Bos taurus
101102018 Ovis aries
19743 Mus musculus
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