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Cooperates with PTBP1 to modulate regulated alternative splicing events. Additionally we are shipping Ribonucleoprotein, PTB-Binding 1 Proteins (3) and many more products for this protein.
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Human Polyclonal RAVER1 Primary Antibody for EIA, WB - ABIN954469
Lee, Rangarajan, Yogesha, Izard: Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. in Structure (London, England : 1993) 2009
Show all 5 references for ABIN954469
Mouse (Murine) Monoclonal RAVER1 Primary Antibody for IF, WB - ABIN238326
Zieseniss, Schroeder, Buchmeier, Schoenenberger, van den Heuvel, Jockusch, Illenberger: Raver1 is an integral component of muscle contractile elements. in Cell and tissue research 2007
Show all 3 references for ABIN238326
Cow (Bovine) Polyclonal RAVER1 Primary Antibody for WB - ABIN2776618
Romanelli, Lorenzi, Avesani, Morandi: Functional characterization of the ribonucleoprotein, PTB-binding 1/Raver1 promoter region. in Gene 2007
Cow (Bovine) Polyclonal RAVER1 Primary Antibody for IHC, WB - ABIN2776619
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004
RAVER1 specifically regulates MDA5 (show IFIH1 Antibodies) activity, revealing a mechanism of differential regulation of MDA5 (show IFIH1 Antibodies)- and RIG-I (show DDX58 Antibodies)-mediated innate antiviral response.
These binding assays show that raver1 forms a ternary complex with metavinculin (show VCL Antibodies) and vinculin (show VCL Antibodies) mRNA.
Raver1 gene promoter region shares common features of ubiquitously expressed gene with the interacting splicing regulator PTB (show PTBP2 Antibodies)
RAVER1 interactions with vinculin (show VCL Antibodies) and RNA suggest a feed forward pathway in directing messenger RNA to focal adhesions.
PTB (show PTBP1 Antibodies)-mediated splicing repression involves recruitment of raver1 as a potent splicing co-repressor.
In mice, raver1 might link gene expression with structural functions of muscle contractility during muscle differentiation.
raver1 may play an important role for the regulation of neuronal synaptic plasticity, possibly by controlling especially the late LTP (show SCP2 Antibodies) via posttranscriptional mechanisms.
Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
, ribonucleoprotein, PTB-binding 1
, protein raver-1
, ribonucleoprotein PTB-binding 1
, RAVER1 homolog