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Ring Finger Protein 135 Proteins (RNF135)

The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Additionally we are shipping Ring Finger Protein 135 Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF135 84282 Q8IUD6
RNF135 71956 Q9CWS1
RNF135 303350 Q5M929
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Top Ring Finger Protein 135 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,153.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RNF135 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Ring Finger Protein 135 (RNF135) Interaction Partners

Human Ring Finger Protein 135 (RNF135) interaction partners

  1. Data showed that the presence of the RNF135 K115 variant in the genotype of patients with autism was statistically significant.

  2. Riplet-mediated K63-linked polyubiquitination released RIG-I (show DDX58 Proteins) RD autorepression, which allowed the access of positive factors to the RIG-I (show DDX58 Proteins) protein.

  3. REUL is an E3 ubiquitin ligase (show MUL1 Proteins) of RIG-I (show DDX58 Proteins) and specifically stimulates RIG-I (show DDX58 Proteins)-mediated innate antiviral activity

  4. These data identify RNF135 as causative of a new overgrowth syndrome and demonstrate that RNF135 haploinsufficiency contributes to the phenotype of NF1 (show NF1 Proteins) microdeletion cases.

  5. identify an alternative factor, Riplet/RNF135, that promotes RIG-I (show DDX58 Proteins) activation independent of TRIM25 (show TRIM25 Proteins)

  6. RNF135 mutations are not present in patients with Sotos syndrome-like features.

Mouse (Murine) Ring Finger Protein 135 (RNF135) interaction partners

  1. Riplet-mediated K63-linked polyubiquitination released RIG-I (show DDX58 Proteins) RD autorepression, which allowed the access of positive factors to the RIG-I (show DDX58 Proteins) protein.

  2. Riplet is essential for regulating RIG-I (show DDX58 Proteins)-mediated innate immune response against RNA virus infection in vivo.

Ring Finger Protein 135 (RNF135) Protein Profile

Protein Summary

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with RNF135

  • ring finger protein 135 (RNF135)
  • ring finger protein 135 (Rnf135)
  • 0610037N03Rik protein
  • 2410006N06Rik protein
  • LRRGT00184 protein
  • MMFD protein
  • REUL protein
  • Riplet protein

Protein level used designations for RNF135

E3 ubiquitin-protein ligase RNF135 , RIG-I E3 ubiquitin ligase , Riplet , U 2-3-0

GENE ID SPECIES
84282 Homo sapiens
480614 Canis lupus familiaris
511125 Bos taurus
71956 Mus musculus
303350 Rattus norvegicus
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