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Ring Finger Protein 169 Proteins (RNF169)

Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Additionally we are shipping RNF169 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF169 254225 Q8NCN4
RNF169 108937 E9Q7F2
Rat RNF169 RNF169 685009  
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Top RNF169 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RNF169 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Ring Finger Protein 169 (RNF169) Interaction Partners

Human Ring Finger Protein 169 (RNF169) interaction partners

  1. RNF169 as a component in DNA damage signal transduction and adds to the complexity of regulatory ubiquitylation in genome stability maintenance.

  2. RNF168, its paralog RNF169, RAD18, and the BRCA1-interacting RAP80 protein accumulate at DNA double strand break sites through the use of bipartite modules composed of ubiquitin binding domains.

  3. results show that RNF169 functions in a noncanonical fashion to harness RNF168 (show RNF168 Proteins)-mediated protein recruitment to DSB-containing chromatin, thereby contributing to regulation of DSB repair pathway utilization.

RNF169 Protein Profile

Protein Summary

Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin- protein ligase activity is not required for regulation of DSBs repair (By similarity).

Gene names and symbols associated with RNF169

  • ring finger protein 169 (RNF169)
  • ring finger protein 169 (Rnf169)
  • 2900057K09Rik protein

Protein level used designations for RNF169

E3 ubiquitin-protein ligase RNF169

GENE ID SPECIES
419055 Gallus gallus
100739168 Sus scrofa
525756 Bos taurus
254225 Homo sapiens
609300 Canis lupus familiaris
108937 Mus musculus
685009 Rattus norvegicus
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