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Calcium-binding protein. Additionally we are shipping S100A16 Proteins (15) and S100A16 Kits (13) and many more products for this protein.
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Data show that overexpression of S100 calcium binding protein A16 protein (S100A16) activated AKT (show AKT1 Antibodies) protein and ERK (show EPHB2 Antibodies) signaling pathways.
These results indicate that S100 calcium binding protein A16 is a differentiation promoting protein and might function as a tumor suppressor in oral squamous cell carcinoma.
Co-expression of S100A14 (show S100A14 Antibodies) and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion
S100A16 had a potential function to regulate some embryonic transcription factors to promote epithelial-mensenchymal transition in breast cancer cells which may be an important target site for the therapy of breast cancer.
The presence of hydrophobic interactions stronger than for other S100 proteins, present in the closed form of S100A16 between the third and fourth helices, likely make the closed structure of the second EF-hand particularly stable.
S100A16 inhibits osteogenesis but stimulates adipogenesis by increasing the transcription of PPARgamma (show PPARG Antibodies) and decreasing the transcription of RUNX2 (show RUNX2 Antibodies).
High-calcium diets may lead to nuclear exclusion of S100A16, which results in the inhibition of adipogenesis and enhanced insulin (show INS Antibodies) sensitivity.
This study showed that S100A16 protein is a novel adipogenesis-promoting factor and that increased expression of S100A16 in 3T3-L1 adipocytes can have a negative impact on insulin (show INS Antibodies) sensitivity.
In situ hybridization analysis and immunohistochemistry revealed a widespread distribution in the mouse brain. Furthermore, S100A16 expression was found to be astrocyte-specific
Calcium-binding protein. Binds one calcium ion per monomer (By similarity).
S100 calcium-binding protein A16
, aging-associated gene 13 protein
, aging-associated protein 13
, protein S100-A16
, protein S100-F