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The protein encoded by S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping S100A2 Antibodies (33) and S100A2 Kits (8) and many more products for this protein.
Showing 10 out of 15 products:
Human S100A2 Protein expressed in Human Cells - ABIN2002264
Lapi, Iovino, Fontemaggi, Soliera, Iacovelli, Sacchi, Rechavi, Givol, Blandino, Strano: S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation. in Oncogene 2006
Show all 5 references for ABIN2002264
Human S100A2 Protein expressed in Escherichia coli (E. coli) - ABIN2002266
Gimona, Lando, Dolginov, Vandekerckhove, Kobayashi, Sobieszek, Helfman: Ca2+-dependent interaction of S100A2 with muscle and nonmuscle tropomyosins. in Journal of cell science 1997
Show all 5 references for ABIN2002266
Human S100A2 Protein expressed in Escherichia coli (E. coli) - ABIN667377
Nagy, Brenner, Markadieu, Chaboteaux, Camby, Schäfer, Pochet, Heizmann, Salmon, Kiss, Decaestecker: S100A2, a putative tumor suppressor gene, regulates in vitro squamous cell carcinoma migration. in Laboratory investigation; a journal of technical methods and pathology 2001
Show all 2 references for ABIN667377
The potential of cytoplasmic S100A2 overexpression as a predictor of recurrence risk in oral squamous cell carcinoma patients.
Data show higher expression level of S100A2 in high-invasive cholangiocarcinoma Cell Line suggesting it as potential marker of tumor progression and novel therapeutic target.
Our investigation complements the current understanding of laryngeal cancer progression. Furthermore, this study supports the concept that enhanced expression of S100A2 may be a promising strategy in developing novel cancer therapeutic drugs.
These data demonstrate the importance of S100A2 downstream of the BRCA1/DeltaNp63 signalling axis in modulating transcriptional responses and enforcing growth control mechanisms through destabilisation of mutant p53 (show TP53 Proteins).
loss of S100A2 expression contributes to Ggastric cancer development and progression.
S100A2 protumorigenic actions and its involvement in TGF-beta (show TGFB1 Proteins)-mediated cancer cell invasion and epithelial-mesenchymal transition.
Expression of S100A2 in cholangiocarcinoma cells significantly correlated with the histological grade, lymph node metastasis, clinical stage, and a poor survival rate of the patients. Thus it is a strong tumor marker for the cancer.
Data indicate that S100A2 expression predicts longer disease-free survival (DFS (show FST Proteins)) and overall survival (OS) in patients treated with adjuvant therapy and should be evaluated as a predictive biomarker.
In conclusion, data from the present study demonstrated that loss of S100A2 expression contributes to gastric cancer development and progression
Data indicate S100A2 and S100P (show S100P Proteins) proteins as novel Ca2 (show CA2 Proteins)+-dependent regulators of the CHIP-proteasome pathway.
S100A2 and S100A6 (show S100A6 Proteins) interact with another TPR (show GRID2 Proteins) protein Tom70 (show TOMM70A Proteins) and regulate the Tom70 (show TOMM70A Proteins)-ligand interaction in vitro
Survival after UVA irradiation was greater in human keratinocytes compared to mouse skin with no S100A2 expression, showing a protective role for S100A2. A S100A2-dependent difference was observed in the induction of Cxcl13 (show CXCL13 Proteins) transcripts in transgenic mice.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
S100 calcium binding protein A2
, S100 calcium-binding protein A2
, protein S100-A2
, predicted gene, EG628324