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anti-S100 Calcium Binding Protein A4 (S100A4) Antibodies

The protein encoded by S100A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping s100a4 Proteins (39) and s100a4 Kits (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
S100A4 6275 P26447
S100A4 20198 P07091
S100A4 24615 P05942
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Top anti-s100a4 Antibodies at antibodies-online.com

Showing 10 out of 233 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), WB S100A4 Antibody (N-term)  western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the S100A4 antibody detected the S100A4 protein (arrow). S100A4 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of S100A4 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cat Rabbit Un-conjugated IHC (p) 0.5 mL Log in to see 10 to 12 Days
$658.35
Details
Human Rabbit Un-conjugated IHC (p) 0.1 mg Log in to see 10 to 12 Days
$531.30
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN334485 (0.03µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB ABIN188680 (0.03?g/ml) staining of Human Placenta lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Immunohistochemistry: S100A4 Antibody [ABIN1886804] - 2.5ug/ml staining of paraffin embedded Human Small Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to S100A4 on HeLa cell (antibody concentration 15 µg/mL). Western Blot analysis of S100A4 expression in transfected 293T cell line by S100A4 monoclonal antibody (M01), clone 1F12-1G7. Lane 1: S100A4 transfected lysate(11.7 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: S100A4 Antibody [NBP1-89402] - Staining of human liver shows strong cytoplasmic positivity in bile duct cells. Western Blot: S100A4 Antibody [NBP1-89402] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418991) 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μL Log in to see 6 to 8 Days
$500.50
Details

S100A4 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-s100a4 Antibodies

  1. Human Monoclonal s100a4 Primary Antibody for IF, WB - ABIN395081 : van Dieck, Lum, Teufel, Fersht: S100 proteins interact with the N-terminal domain of MDM2. in FEBS letters 2010 (PubMed)
    Show all 5 references for ABIN395081

  2. Human Polyclonal s100a4 Primary Antibody for IHC (p), IHC - ABIN188680 : Jiang, Xu, Mao, Li, Fang, Zhou, Liu, He, Zhao, Yang, Dai: Rheb/mTORC1 signaling promotes kidney fibroblast activation and fibrosis. in Journal of the American Society of Nephrology : JASN 2013 (PubMed)
    Show all 2 references for ABIN188680

  3. Human Polyclonal s100a4 Primary Antibody for IHC, IHC (p) - ABIN4351669 : Laguë, Detmar, Paquet, Boyer, Richards, Adamson, Boerboom: Decidual PTEN expression is required for trophoblast invasion in the mouse. in American journal of physiology. Endocrinology and metabolism 2010 (PubMed)
    Show all 2 references for ABIN4351669

  4. Mouse (Murine) Polyclonal s100a4 Primary Antibody for IHC (p), WB - ABIN655727 : Miranda, Loeser, Yammani: Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN655727

  5. Human Polyclonal s100a4 Primary Antibody for IHC, ELISA - ABIN334485 : Li, Bresnick: The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA. in Cancer research 2006 (PubMed)
    Show all 2 references for ABIN334485

  6. Cat (Feline) Polyclonal s100a4 Primary Antibody for IHC (p) - ABIN181369 : Schäfer, Heizmann: The S100 family of EF-hand calcium-binding proteins: functions and pathology. in Trends in biochemical sciences 1996 (PubMed)
    Show all 2 references for ABIN181369

  7. Human Polyclonal s100a4 Primary Antibody for IHC (p) - ABIN181370 : Ilg, Schäfer, Heizmann: Expression pattern of S100 calcium-binding proteins in human tumors. in International journal of cancer. Journal international du cancer 1996 (PubMed)
    Show all 2 references for ABIN181370

More Antibodies against s100a4 Interaction Partners

Human S100 Calcium Binding Protein A4 (S100A4) interaction partners

  1. Results found that CNE-1 nasopharyngeal carcinoma cell (NPC (show NPC1 Antibodies)) line expressing S100A4 showed significantly increased invasion ability in vitro and in vivo. Also, it seems that aberrant DNA hypomethylation of its promotor region might lead to the metastasis progression in EBV-associated NPC (show NPC1 Antibodies).

  2. Oct-1 (show POU2F1 Antibodies) modifies S100A4 exchange between intra- and extracellular compartments in Namalwa cells and increases their sensitivity to glucocorticoids.

  3. ChIP studies showed that the S100A4 protein binds to the GDF15 (show GDF15 Antibodies) promoter, implicating S100A4 in GDF15 (show GDF15 Antibodies) regulation at the transcriptional level.

  4. Cell invasion (matrigel) was reduced only in the Hs578T cells (p < 0.01). Silencing decreased the expression of the prometastatic molecules S100A4 and TGFbetaR2 in both cell lines and CD44 (show CD44 Antibodies) in Hs578T cells .We conclude that ECM1 (show ECM1 Antibodies) is a key player in the metastatic process and regulates the actin cytoskeletal architecture of aggressive breast cancer cells at least in part via alterations in S100A4 and Rho A (show RHOA Antibodies).

  5. Aberrant S100A4 expression may predictendometrial cancer (EC) progression and play an important role in regulating EC cell invasion through Epithelial-mesenchymal transition (EMT (show ITK Antibodies)) regulation.

  6. S100A4 could promote the invasion ability of breast cancer cells via EMT (show ITK Antibodies), more importantly, it could participate in EMT (show ITK Antibodies) via regulating MMP2 (show MMP2 Antibodies) in breast cancer.

  7. our results demonstrate not only that high expression of S100A4 contributes to an aggressive phenotype of EC, but also that its elevated expression is closely related to the MELF (show EPM2A Antibodies) histopathological pattern.

  8. S100A4, A8, and A9 proteins represent promising marker genes to evaluate the risk potential of suspicious oral lesions in molecular pathology.

  9. Increased S100A4 expression is associated with thyroid papillary carcinoma.

  10. Comparative analysis of various tumor lines showed no clear correlation between the expression level of Mts1/S100A4 and the content of Oct-1 (show POU2F1 Antibodies). However, at stable transfection of tumor cells with Oct (show Plxna2 Antibodies)-1A, Oct (show Plxna2 Antibodies)-1L, and Oct (show Plxna2 Antibodies)-1X isoforms we detected an elevated level of Oct-1 (show POU2F1 Antibodies), which stimulated Mts1/S100A4 secretion.

Mouse (Murine) S100 Calcium Binding Protein A4 (S100A4) interaction partners

  1. These findings provide further evidence on extracellular S100A4 as paracrine mediator of prometastatic endothelial dysfunction involving its interaction with RAGE (show AGER Antibodies).

  2. this study has demonstrated a crucial role for retinoic acid in promoting IL-22 (show IL22 Antibodies) production and tempering dendritic cell function through downregulating S100A4 protein during viral hepatitis

  3. Extracellular S100A4 is important for the regulation of bone formation by activating the NF-kappaB (show NFKB1 Antibodies) signaling pathway in osteoblasts.

  4. Interaction of extracellular S100A4 with RAGE (show AGER Antibodies) prompts prometastatic activation of melanoma cells.

  5. Our results indicated that RNV was ameliorated by Ad-S100A4-RNAi transfer in a mouse model of OIR through mediation of the anti-apoptotic effect of Bcl-2 (show BCL2 Antibodies) by reducing the expression of CREB (show CREB1 Antibodies).

  6. The thymic CD45 (show PTPRC Antibodies)-FSP1+ cells are a subpopulation of fibroblasts, which is crucial for the maintenance and regeneration of thymic epithelial cells.

  7. Enhanced S100A4 expression was observed in remodeled intrapulmonary arteries of mice with smoke-induced emphysema.

  8. Downregulation of AKT3 (show AKT3 Antibodies) increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4.

  9. S100A4 promotes liver fibrosis by activating HSCs, which may represent a potential target for anti-fibrotic therapies.

  10. The S100A4 blocking antibody (6B12) reduces tumor growth and metastasis in a model of spontaneous breast cancer.

s100a4 (S100A4) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with S100A4

  • S100 calcium binding protein A4 (S100A4) antibody
  • S100 calcium-binding protein A4 (LOC100349003) antibody
  • S100 calcium binding protein A4 (S100a4) antibody
  • S100 calcium-binding protein A4 (S100a4) antibody
  • 18A2 antibody
  • 42a antibody
  • Capl antibody
  • FSp1 antibody
  • metastasin antibody
  • Mts1 antibody
  • P9ka antibody
  • PeL98 antibody
  • pk9a antibody
  • RNP9KA antibody
  • S100A4 antibody

Protein level used designations for S100A4

S100 calcium binding protein A4 , S100 calcium-binding protein A4 , S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) , fibroblast-specific protein-1 , leukemia multidrug resistance associated protein , malignant transformation suppression 1 , placental calcium-binding protein , protein Mts1 , protein S100-A4 , S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) , metastasin , S100 calcium-binding protein A4 (calcium protein,calvasculin, metastasin, murine placental homolog) , placental calcium-binding protein homolog , calvasculin , metastatic cell protein , protein 18A2 , P9K , Protein 9 Ka homologous to calcium-binding protein , nerve growth factor-induced protein 42A

GENE ID SPECIES
457320 Pan troglodytes
715115 Macaca mulatta
100349003 Oryctolagus cuniculus
6275 Homo sapiens
403787 Canis lupus familiaris
101083141 Felis catus
282343 Bos taurus
20198 Mus musculus
100723950 Cavia porcellus
24615 Rattus norvegicus
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