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anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) Antibodies

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. Additionally we are shipping SETD7 Proteins (11) and SETD7 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SETD7 80854 Q8WTS6
SETD7 73251 Q8VHL1
SETD7 689954  
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Top anti-SETD7 Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB Immunoblot analysis.,.Recombinant SET7/9 was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-SET7/9(1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicated SET7/9(~50Da). 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-SET9 Ctr Pab (ABIN387997) is used in Western blot to detect SET9 in mouse brain tissue lysate. Western blot analysis of SET9(arrow) using rabbit polyclonal SET9 Antibody(ABIN387997). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SET9 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SETD7 / SET7 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960912 dilution 1:100. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC219244 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SETD7 antibody (ABIN2454914), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SETD7 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SETD7. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SETD7 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SETD7. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-SETD7 mouse monoclonal antibody (ABIN2454881) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SETD7 (RC219244). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SETD7 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SETD7. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details

SETD7 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-SETD7 Antibodies

  1. Human Polyclonal SETD7 Primary Antibody for EIA, IHC (p) - ABIN356694 : Wysocka, Myers, Laherty, Eisenman, Herr: Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. in Genes & development 2003 (PubMed)
    Show all 5 references for ABIN356694

  2. Human Polyclonal SETD7 Primary Antibody for EIA, WB - ABIN356695 : Xiao, Jing, Wilson, Walker, Vasisht, Kelly, Howell, Taylor, Blackburn, Gamblin: Structure and catalytic mechanism of the human histone methyltransferase SET7/9. in Nature 2003 (PubMed)
    Show all 5 references for ABIN356695

  3. Human Polyclonal SETD7 Primary Antibody for IHC (p), WB - ABIN387997 : Kwon, Chang, Kwak, Lee, Joachimiak, Kim, Lee, Cho: Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. in The EMBO journal 2003 (PubMed)
    Show all 4 references for ABIN387997

  4. Human Polyclonal SETD7 Primary Antibody for WB - ABIN2783571 : Subramanian, Jia, Kapoor-Vazirani, Powell, Collins, Sharma, Peng, Cheng, Vertino: Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. in Molecular cell 2008 (PubMed)

  5. Human Monoclonal SETD7 Primary Antibody for EIA, IHC (p) - ABIN121150 : Nishioka, Chuikov, Sarma, Erdjument-Bromage, Allis, Tempst, Reinberg: Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. in Genes & development 2002 (PubMed)

More Antibodies against SETD7 Interaction Partners

Human SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. Lysine methylation by SETD7 is important for the fine-tuning of reactive oxygen species signaling through its regulation on pro-inflammatory responses.

  2. Knock-down of SETD7 causes differentiation defects in human embryonic stem cell including delay in both the silencing of pluripotency-related genes and the induction of differentiation genes.

  3. Unleashed expression of Mdm2 (show MDM2 Antibodies) in cancer patients with diminished expression of Set7/9 is associated with poor survival outcome.

  4. Based on our results miR (show MLXIP Antibodies)-153 inhibits proliferation and suppresses EMT (show ITK Antibodies) and the invasive potential of ovarian cancer cells through downregulation of SET7 and ZEB2 (show ZEB2 Antibodies), supporting the pursuit of miR (show MLXIP Antibodies)-153 as a potential target for ovarian cancer intervention.

  5. Findings indicate the regulation of Wnt/beta-catenin signaling and the role of SET domain-containing protein 7/9 (SET7/9) in cancer cells.

  6. Set7-induced epigenetic changes contribute to vascular dysfunction in patients with T2DM.

  7. SET9 enriches at hypoxia response elements sites of HIF-1 (show HIF1A Antibodies) responsive glycolytic genes and stabilizes HIF-1alpha (show HIF1A Antibodies) at these sites in hypoxia.

  8. Set7/9 is a potential biomarker in tumour cells and is associated with overexpressed E2F1 (show E2F1 Antibodies) activity.

  9. Results show that histone-lysine N-methyltransferase Set7 facilitates hepatitis C virus (HCV) replication through the attenuation of interferon-alpha (IFN-alpha (show IFNA Antibodies)) signaling pathways and IFN-related effectors.

  10. Set7-dependent gene expression changes that occurred independent of H3K4m1 may involve transcription factor lysine methylation events.

Mouse (Murine) SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. SETD7 is required for Wnt (show WNT2 Antibodies)-driven intestinal tumorigenesis and regeneration. SETD7-dependent methylation of YAP (show YAP1 Antibodies) facilitates Wnt (show WNT2 Antibodies)-induced nuclear accumulation of beta-catenin (show CTNNB1 Antibodies).

  2. SET7/9 regulates Nos2 expression through methylation of H3K4 in beta cells.

  3. Data indicate that the ability of transcription factor Pdx1 (show PDX1 Antibodies) to regulate genes in beta cells is partially dependent upon its methylation by methyltransferase Set7/9.

  4. study found that Set7 is a modifier of the Hippo pathway. Mice that lack Set7 have a larger progenitor compartment in the intestine, coinciding with increased expression of Yes-associated protein target genes.

  5. The response to hyperglycemia in vascular endothelial cells involves Set7 mediated changes in chromatin remodeling and gene expression.

  6. Set7/9-mediated methylation of p53 (show TP53 Antibodies) does not represent a major regulatory event and does not appreciably control p53 (show TP53 Antibodies) activity in vivo.

  7. Set7/9 is dispensable for p53 (show TP53 Antibodies) function in the mouse.

  8. Define a biological function for Set7 in muscle differentiation and provide a molecular mechanism by which Set7 modulates myogenic transcription factors during muscle differentiation.

  9. Pdx1 (show PDX1 Antibodies)-dependent Set7/9 expression may be crucial to enhancing chromatin accessibility and transcription of beta-cell genes.

  10. Methylation of p53 (show TP53 Antibodies) by Set7 mediates p53 (show TP53 Antibodies) acetylation and activity in vivo.

SETD7 Antigen Profile

Protein Summary

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the -K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Gene names and symbols associated with SETD7

  • SET domain containing (lysine methyltransferase) 7 (SETD7) antibody
  • SET domain containing (lysine methyltransferase) 7 (setd7) antibody
  • SET domain containing (lysine methyltransferase) 7 (Setd7) antibody
  • 1600028F23Rik antibody
  • H3K4MT antibody
  • KMT7 antibody
  • mKIAA1717 antibody
  • Set7 antibody
  • Set7/9 antibody
  • SET9 antibody
  • zgc:92330 antibody
  • zgc:101860 antibody

Protein level used designations for SETD7

H3-K4-HMTase SETD7 , SET domain-containing protein 7 , histone H3-K4 methyltransferase SETD7 , histone H3-lysine 4-specific methyltransferase , histone-lysine N-methyltransferase SETD7 , lysine N-methyltransferase 7 , H3-K4 methyltransferase

GENE ID SPECIES
80854 Homo sapiens
436729 Danio rerio
73251 Mus musculus
689954 Rattus norvegicus
476079 Canis lupus familiaris
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