anti-SET and MYND Domain Containing 2 (SMYD2) Antibodies

SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006. Additionally we are shipping SET and MYND Domain Containing 2 Proteins (12) and SET and MYND Domain Containing 2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMYD2 56950 Q9NRG4
SMYD2 226830 Q8R5A0
SMYD2 289372 Q7M6Z3
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Top anti-SET and MYND Domain Containing 2 Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-SMYD2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>ACHN cell lysate WB Suggested Anti-SMYD2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: ACHN cell lysate <br /> SMYD2 is supported by BioGPS gene expression data to be expressed in ACHN 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated ChIP, WB <b>WB Suggested Anti-SMYD2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>SH-SYSY cell lysate Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of SYMD2 (arrow) using rabbit polyclonal SYMD2 Antibody (N-term) (ABIN387897).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SYMD2 gene (Lane 2) (Origene Technologies). SMYD2 Antibody (N-term) (ABIN387897) western blot analysis in NCI-H292 cell line lysates (35 µg/lane).This demonstrates the SMYD2 antibody detected the SMYD2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$357.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ICC, IF, IP, WB Western Blot: SMYD2 Antibody [NBP2-20429] - Sample (30 ug of whole cell lysate) A: Hela B: HCT116 10% SDS PAGE gel, diluted at 1:1000. Immunocytochemistry/Immunofluorescence: SMYD2 Antibody [NBP2-20429] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 16 Days
$460.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p)   100 μL Log in to see 3 to 7 Days
$295.90
Details

SMYD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SET and MYND Domain Containing 2 Antibodies

  1. Human Polyclonal SMYD2 Primary Antibody for ELISA, WB - ABIN4369823 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal SMYD2 Primary Antibody for ChIP, WB - ABIN2784266 : Shibamoto, Ogino, Suzuki, Takemoto, Araki, Isobe, Tsuchida, Nakamura, Kenjo, Suzuki, Hosono, Tokumaru, Ishihara, Kato, Ii, Hayabuchi: Primary central nervous system lymphoma in Japan: changes in clinical features, treatment, and prognosis during 1985-2004. in Neuro-oncology 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SET and MYND Domain Containing 2 Interaction Partners

Human SET and MYND Domain Containing 2 (SMYD2) interaction partners

  1. The SMYD2 may promote BMP signaling by directly methylating BMPR2, which, in turn, stimulates BMPR2 kinase activity and activation of the BMP pathway.

  2. Knockdown of SMYD2 as well as treatment with a SMYD2 inhibitor in two NSCLC cell lines with an EML4 (show EML4 Antibodies)-ALK (show ALK Antibodies) gene significantly attenuated the phosphorylation levels of the EML4 (show EML4 Antibodies)-ALK (show ALK Antibodies) protein.

  3. SMYD2 knockdown confers relative resistance to human AML (show RUNX1 Antibodies) cells against multiple classes of DNA damaging agents.

  4. Substrate crevices of Smyd2 and Smyd3 (show SMYD3 Antibodies) show distinct features in terms of spatial, hydration, and electrostatic properties that emphasize their characteristic modes of substrates interaction and entry pathways for inhibitor binding.

  5. High expression of SMYD2 is associated with chronic lymphocytic leukemia.

  6. Study reveals a collection of 10 enriched sequence motifs in Kme1 sites that were identified upon SMYD2 overexpression which were also downregulated in response to SMYD2 knockdown. These findings suggest that these motifs reflect the substrate specificity of SMYD2 in esophageal squamous cell carcinoma cell line.

  7. Results show that high expression levels of SMYD2, SETD3 (show SETD3 Antibodies), and NO66 (show C14orf169 Antibodies) in renal cell tumors. Their low expression levels were significantly associated with shorter disease-specific and disease-free survival.

  8. Suggest that SMYD2 plays a role in tumor progression and might be a useful prognosticator in HPV-unrelated, nonmultiple head and neck squamous cell carcinomas.

  9. SMYD2-mediated methylation negatively regulates PTEN (show PTEN Antibodies) tumor suppressor activity and results in activation of the phosphatidylinositol 3-kinase-AKT (show AKT1 Antibodies) pathway.

  10. Comprehensive motif-based searches and mutational analysis further established four additional substrates of SMYD2.

Mouse (Murine) SET and MYND Domain Containing 2 (SMYD2) interaction partners

  1. two positive feedback loops that integrate epigenetic regulation and renal inflammation in cyst development: SMYD2/IL-6 (show IL6 Antibodies)/STAT3 (show STAT3 Antibodies)/SMYD2 and SMYD2/TNF-alpha (show TNF Antibodies)/NF-kappaB (show NFKB1 Antibodies)/SMYD2.

  2. a pivotal role for SMYD2 in promoting pancreatic cancer.

  3. Data show that histone methyltransferase Smyd2 inhibits macrophage interleukin 6 (IL-6 (show IL6 Antibodies)) and tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies)) production. production.

  4. Smyd2 is a lysine methyltransferase which has, next to its nuclear activity, specific regulatory functions in the cytoplasm of heart and skeletal muscle cells.

  5. Smyd2, similar to Smyd3 (show SMYD3 Antibodies), interacts with RNA Polymerase II as well as to the RNA helicase, HELZ (show HELZ Antibodies)

  6. Sin3A (show SIN3A Antibodies)-mediated deacetylation within the coding regions of active genes is directly linked to the histone methyltransferase activity of Smyd2 [Symd2]

  7. results show that Smyd2 negatively regulates p53 (show TP53 Antibodies)-responsive genes in a p53 (show TP53 Antibodies)-dependent manner

Zebrafish SET and MYND Domain Containing 2 (SMYD2) interaction partners

  1. Findings suggest that SMYD2 (SET and MYND domain containing protein 2), a histone lysine methyltransferase, plays a critical role at early stages of development.

SET and MYND Domain Containing 2 (SMYD2) Antigen Profile

Protein Summary

SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006

Gene names and symbols associated with SMYD2

  • SET and MYND domain containing 2 (SMYD2) antibody
  • SET and MYND domain containing 2 (LOC100230503) antibody
  • SET and MYND domain containing 2 (Smyd2) antibody
  • SET and MYND domain containing 2 (smyd2) antibody
  • SET and MYND domain containing 2a (smyd2a) antibody
  • 1110020E07Rik antibody
  • 4930402C15 antibody
  • HSKM-B antibody
  • im:7146196 antibody
  • KMT3C antibody
  • smyd2 antibody
  • smyd2-a antibody
  • wu:fc02f02 antibody
  • zgc:110553 antibody
  • Zmynd14 antibody

Protein level used designations for SMYD2

SET and MYND domain containing 2 , SET and MYND domain-containing protein 2-like , N-lysine methyltransferase SMYD2 , SET and MYND domain-containing protein 2 , histone methyltransferase SMYD2 , lysine N-methyltransferase 3C , zinc finger, MYND domain containing 14 , Histone methyltransferase SMYD2 , SET and MYND domain-containing 2 , HSKM-B protein , Histone methyltransferase SMYD2-A , N-lysine methyltransferase SMYD2-A , SET and MYND domain-containing protein 2A , histone methyltransferase SMYD2-A

GENE ID SPECIES
457729 Pan troglodytes
709375 Macaca mulatta
100023305 Monodelphis domestica
100052774 Equus caballus
100230503 Taeniopygia guttata
100344249 Oryctolagus cuniculus
100404005 Callithrix jacchus
100439768 Pongo abelii
100603309 Nomascus leucogenys
56950 Homo sapiens
226830 Mus musculus
421361 Gallus gallus
480026 Canis lupus familiaris
100294706 Sus scrofa
615229 Bos taurus
289372 Rattus norvegicus
379943 Xenopus laevis
541423 Danio rerio
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