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SFRS Protein Kinase 2 Proteins (SRPK2)

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Additionally we are shipping SFRS Protein Kinase 2 Antibodies (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRPK2 20817 O54781
SRPK2 6733 P78362
Rat SRPK2 SRPK2 296753  
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Top SFRS Protein Kinase 2 Proteins at antibodies-online.com

Showing 5 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$154.00
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

SRPK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,

More Proteins for SFRS Protein Kinase 2 (SRPK2) Interaction Partners

Mouse (Murine) SFRS Protein Kinase 2 (SRPK2) interaction partners

  1. SRPK2 may contribute to the formation of hyperphosphorylated tau and the pathogenesis of Alzheimer disease.

  2. Interaction of Akt (show AKT1 Proteins)-phosphorylated SRPK2 with 14-3-3 (show YWHAQ Proteins) mediates cell cycle and cell death in neurons.

Human SFRS Protein Kinase 2 (SRPK2) interaction partners

  1. Data indicate serine/arginine-rich protein (show MANF Proteins) kinases SRPK1 (show SRPK1 Proteins)/2/SRPIN340 complexes by molecular docking and molecular dynamics.

  2. A conserved electronegative docking groove in SRPK2 is responsible for substrate binding.

  3. the BLRF2 RS motif is phosphorylated by SRPK2 and is important for viral replication.

  4. Our results demonstrate that SRPK1 (show SRPK1 Proteins) and SRPK2 are host factors essential for Hepatitis C virus replication.

  5. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: SRPK2.

  6. Both SRPK1 and SRPK2 are most likely the cellular protein kinases mediating HBV core protein phosphorylation during viral infection and therefore represent important host cell targets for therapeutic intervention in HBV infection.

  7. negative role of SRPK1 and SRPK2 in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein

  8. SRPK2 knock down results in hypophosphorylation of the arginine-serine (RS) domain-containing human PRP28 protein (PRP28, also known as DDX23), and destabilizes PRP28 association with the tri (show VANGL2 Proteins)-snRNP (show LSM2 Proteins).

  9. overexpression of SRPK2 is associated with phosphorylating acinus (show ACIN1 Proteins) and regulating its stimulatory effects on cyclin A1 (show CCNA1 Proteins) expression, contributing to leukemia cell proliferation

  10. Interaction of Akt (show AKT1 Proteins)-phosphorylated SRPK2 with 14-3-3 (show YWHAQ Proteins) mediates cell cycle and cell death in neurons.

SFRS Protein Kinase 2 (SRPK2) Protein Profile

Protein Summary

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up- regulation. Plays an essential role in splicesomal B complex formation via the phosphorylation of DDX23/PRP28.

Gene names and symbols associated with SFRS Protein Kinase 2 Proteins (SRPK2)

  • SFRS protein kinase 2 (SRPK2)
  • SFRS protein kinase 2 (srpk2)
  • SFRS protein kinase 3 (srpk3)
  • serine/arginine-rich protein specific kinase 2 (Srpk2)
  • SRSF protein kinase 2 (SRPK2)
  • SRSF protein kinase 2 (Srpk2)
  • AW226533 protein
  • AW492537 protein
  • AW547358 protein
  • MGC147832 protein
  • mSRPK2 protein
  • SFRSK2 protein
  • srpk2 protein
  • Wbp6 protein

Protein level used designations for SFRS Protein Kinase 2 Proteins (SRPK2)

SFRS protein kinase 2 , SFRS protein kinase 3 , serine/threonine-protein kinase SRPK2-like , SR-protein-specific kinase 2 , SRSF protein kinase 2 , WW domain binding protein 6 , serine/arginine-rich protein-specific kinase 2 , serine/threonine-protein kinase SRPK2 , SR protein kinase 2 , serine kinase SRPK2 , serine/arginine-rich splicing factor kinase 2 , serine/arginine-rich protein specific kinase 2

GENE ID SPECIES
463641 Pan troglodytes
100050379 Equus caballus
100124819 Xenopus (Silurana) tropicalis
100125041 Xenopus (Silurana) tropicalis
100390282 Callithrix jacchus
20817 Mus musculus
6733 Homo sapiens
296753 Rattus norvegicus
475894 Canis lupus familiaris
417711 Gallus gallus
505945 Bos taurus
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