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The protein encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. Additionally we are shipping SH2B2 Proteins (4) and many more products for this protein.
Showing 7 out of 9 products:
Association between variations in the SH2B2 gene and growth traits in Chinese cattle.
Deletion of liver SH2B1 (show SH2B1 Antibodies) in SH2B2 null mice attenuated very low-density lipoprotein (VLDL) secretion.
APS facilitates c-Cbl (show CBL Antibodies) tyrosine phosphorylation and GLUT4 (show SLC2A4 Antibodies) translocation in response to insulin (show INS Antibodies) in 3T3-L1 adipocytes
Data show that the adapter protein (show GRB10 Antibodies) APS preferentially associates with phosphorylated Tyr (show TYR Antibodies)-568 and Tyr (show TYR Antibodies)-936 of the receptor for stem-cell factor (show KITLG Antibodies) (c-Kit (show KIT Antibodies)).
Lnk (show SH2B3 Antibodies), SH2-B (show SH2B1 Antibodies), and APS have roles in mast cell development, growth, and functions
APS might have a novel regulatory role in actin reorganization and control of B-1 cell compartment size.
Knockdown of the mouse APS gene abolished the insulin (show INS Antibodies)-stimulated phosphorylation of c-Cbl (show CBL Antibodies).
APS appears to play novel negative regulatory roles in BCR signaling, actin reorganization pathways, and control of compartment sizes of B-lineage cells
These results identify Enigma as a novel APS-binding protein and suggest that the APS/Enigma complex plays a critical role in actin cytoskeleton organisation.
SH2-B (show SH2B1 Antibodies), but not APS, is a key positive regulator of energy and glucose metabolism in mice
APS enhanced ligand-dependent multi-ubiquitination of the insulin receptor (IR (show INSR Antibodies)) in CHO (show COL11A1 Antibodies) cells.
Studies indicate that insulin receptor (IR (show INSR Antibodies)) and IGF Type 1 Receptor (IGFR) have been identified as important partners of Grb10 (show GRB10 Antibodies)/14 and SH2B1 (show SH2B1 Antibodies)/B2 adaptors.
We present here a novel stimulatory mechanism of Vav3 (show VAV3 Antibodies) in which APS directly relieves the autoinhibitory CH domain and furthermore enhances its tyrosine phosphorylation by Lck (show LCK Antibodies).
N-terminal residues distal to the phosphotyrosine directly contact residues of the four-helix bundle of the TKB domain of the adapter protein (show TOLLIP Antibodies) APS
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
PRKR-interacting protein 1 homolog
, SH2B adaptor protein 2
, SH2B adapter protein 2-like
, SH2 and PH domain-containing adapter protein APS
, SH2B adapter protein 2
, adapter protein with pleckstrin homology and Src homology 2 domains
, adaptor protein with pleckstrin homology and src homology 2 domains
, insulin receptor substrate 5