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anti-SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) Antibodies

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. Additionally we are shipping SRGAP2 Proteins (3) and SRGAP2 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRGAP2 23380 O75044
SRGAP2 14270 Q91Z67
SRGAP2    
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Top anti-SRGAP2 Antibodies at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IF, ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Cow Goat Un-conjugated EIA, IF   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry of Human liver cancer using SRGAP2 Polyclonal Antibody at dilution of 1:20 200 μL Log in to see 8 to 9 Days
$588.50
Details
Cow Goat Un-conjugated IF, ELISA   100 μL Log in to see 14 Days
$492.18
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$273.90
Details
Cow Goat Un-conjugated IF, WB 0.1 mg Log in to see 6 Days
$412.86
Details
Human Goat Alkaline Phosphatase (AP)   100 μL Log in to see 16 Days
$713.43
Details
Human Goat Biotin   100 μL Log in to see 16 Days
$713.43
Details
Human Goat FITC   100 μL Log in to see 16 Days
$713.43
Details

SRGAP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) , ,
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Rat (Rattus) , ,
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More Antibodies against SRGAP2 Interaction Partners

Human SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) interaction partners

  1. This study illustrated that the role of SRGAP2 (show SRGAP3 Antibodies) protein and its human-specific paralogs in human brain development and evolution.

  2. interlocus gene conversions in SRGAP2 (show SRGAP3 Antibodies)

  3. SRGAP2 (show SRGAP3 Antibodies) has been highly conserved over mammalian evolution, and human is the only lineage wherein gene duplications have occurred. Our analysis indicates that the duplications spread across 80 Mbp (show MBL2 Antibodies) of chromosome 1 at a time corresponding to the transition from Australopithecus to Homo.

  4. Results uncover a new function for ancestral SRGAP2 (show SRGAP3 Antibodies) in promoting dendritic spine maturation and indicate that expression of a human-specific paralog of SRGAP2 (show SRGAP3 Antibodies) in mouse pyramidal neurons extends the phase of spine development and leads to an increased density of longer spines in vivo, a feature characterizing pyramidal neurons in the human neocortex

  5. after Rac-dependent activation of FMNL1, srGAP2 mediates a potent mechanism to limit the duration of Rac action and inhibit formin activity during rapid actin dynamics.

  6. srGAP2 (show SRGAP3 Antibodies) arginine methylation plays important roles in cell spreading and cell migration through influencing membrane protrusion.

  7. FNBP2 gene was linked to IKBKE (show IKBKE Antibodies) and NORE1 (show RASSF5 Antibodies) genes on human chromosome 1q32.1. FNBP2 mRNA was expressed in melanoma, germ cell tumors, chondrosarcoma and retinoblastoma.

Mouse (Murine) SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) interaction partners

  1. The inverse F-BAR domain protein srGAP2 (show SRGAP3 Antibodies) acts through srGAP3 (show SRGAP3 Antibodies) to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma (show ARHGEF16 Antibodies) cells.

  2. Data show that srGAP2 (show SRGAP3 Antibodies) is expressed in zones of neuronal differentiation in many different tissues of the central nervous system.

  3. Study reports that srGAP2 (show SRGAP3 Antibodies) negatively regulates neuronal migration and induces neurite outgrowth and branching through the ability of its F-BAR domain to induce filopodia-like membrane protrusions resembling those induced by I-BAR domains.

SRGAP2 Antigen Profile

Protein Summary

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogous loci on human chromosome 1, resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

Gene names and symbols associated with SRGAP2

  • SLIT-ROBO Rho GTPase activating protein 2 (SRGAP2) antibody
  • SLIT-ROBO Rho GTPase activating protein 2 (Srgap2) antibody
  • 9930124L22Rik antibody
  • AI448945 antibody
  • ARHGAP34 antibody
  • FBP2 antibody
  • Fnbp2 antibody
  • SRGAP2A antibody
  • srGAP3 antibody

Protein level used designations for SRGAP2

SLIT-ROBO Rho GTPase-activating protein 2 , formin binding protein 2 , formin-binding protein 2 , rho GTPase-activating protein 34 , FBP-27 , formin-binding protein 27

GENE ID SPECIES
23380 Homo sapiens
14270 Mus musculus
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