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SCIMP encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and is localized in the immunologic synapse. Additionally we are shipping SCIMP Proteins (2) and many more products for this protein.
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Human Monoclonal SCIMP Primary Antibody for ICC, FACS - ABIN1302508
Draber, Vonkova, Stepanek, Hrdinka, Kucova, Skopcova, Otahal, Angelisova, Horejsi, Yeung, Weiss, Brdicka: SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling. in Molecular and cellular biology 2011
results suggest that SCIMP is involved in signal transduction after MHC-II stimulation and therefore serves as a regulator of antigen presentation and other APC (show APC Antibodies) functions.
SCIMP is strongly phosphorylated after Dectin-1 (show CLEC7A Antibodies) stimulation and that it participates in signal transduction downstream of this important pattern recognition receptor.
This gene encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and is localized in the immunologic synapse. The encoded protein is involved in major histocompatibility complex class II signal transduction and immune synapse formation. Alternatively spliced transcript variants have been found for this gene.
, SLP adapter and CSK-interacting membrane protein
, SLP65/SLP76, Csk-interacting membrane protein
, transmembrane protein C17orf87
, transmembrane protein C17orf87 homolog