You are viewing an incomplete version of our website. Please click to reload the website as full version.

SMC6 Structural Maintenance of Chromosomes 6-Like 1 Proteins (SMC6)

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Additionally we are shipping SMC6 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMC6 79677 Q96SB8
SMC6 67241 Q924W5
Rat SMC6 SMC6 313961  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top SMC6 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SMC6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) Interaction Partners

Human SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) interaction partners

  1. results uncover a novel role for the Smc5 (show SMC5 Proteins)/6 complex as a restriction factor selectively blocking extrachromosomal DNA transcription; by destroying this complex, HBx relieves the inhibition to allow productive hepatitis B virus gene expression

  2. Structural maintenance of chromosomes (SMC (show DYM Proteins)) complexes, which in eukaryotic cells include cohesin, condensin and the Smc5 (show SMC5 Proteins)/6 complex, are central regulators of chromosome dynamics

  3. Depletion of Smc5 (show SMC5 Proteins) and Smc6 resulted in aberrant mitotic chromosome phenotypes that were accompanied by the abnormal distribution of topoisomerase IIalpha (topo IIalpha) and condensins and by chromosome segregation errors

  4. Studies indicate that Nse1 (show FAM84A Proteins) may function as a ubiquitin ligase, and is targeted to chromatin through its interaction with the Smc5 (show SMC5 Proteins)/6 complex.

  5. the human SMC5 (show SMC5 Proteins)/6 complex and the SUMO ligase activity of hMMS21 (show NSMCE2 Proteins) are required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair in human cells

  6. SMC5/6 complex is recruited to nuclease-induced double-strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs.

  7. SMC5 (show SMC5 Proteins)/6 complex facilitates telomere homologous recombination and elongation in alternative lengthening of telomeres cells through SUMOylation of telomere-binding proteins.

  8. The four non-SMC components of the human complex were identified and characterized and it was demonstrated that the MAGEG1 protein is part of this complex.

  9. Nse1 (show FAM84A Proteins) RING-like motif is a protein-protein interaction domain required for Smc5 (show SMC5 Proteins)-Smc6 holocomplex integrity and recruitment to, or retention at, DNA lesions

Mouse (Murine) SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6) interaction partners

  1. Smc6 has a role in the prevention of aberrant recombination events between pericentromeric regions during the first meiotic prophase.

  2. Mice deleted for the SMC6 gene are inviable, and mice mutated at Ser-994 in the SMC6 ATPase domain have a mild phenotype.

SMC6 Protein Profile

Protein Summary

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).

Gene names and symbols associated with SMC6

  • structural maintenance of chromosomes 6 (SMC6)
  • SMC6 protein (smc6)
  • structural maintenance of chromosomes 6 (Smc6)
  • 2810489L22Rik protein
  • 3830418C19Rik protein
  • AA990493 protein
  • AU018782 protein
  • AW742439 protein
  • hSMC6 protein
  • mKIAA4103 protein
  • SMC-6 protein
  • Smc6l1 protein

Protein level used designations for SMC6

SMC6 structural maintenance of chromosomes 6-like 1 , SMC protein 6 , structural maintenance of chromosomes protein 6 , mSMC6

GENE ID SPECIES
421950 Gallus gallus
446077 Takifugu rubripes
79677 Homo sapiens
67241 Mus musculus
475675 Canis lupus familiaris
100517523 Sus scrofa
510381 Bos taurus
313961 Rattus norvegicus
Selected quality suppliers for SMC6 Proteins (SMC6)
Did you look for something else?