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SPARC Related Modular Calcium Binding 1 Proteins (SMOC1)

SMOC1 encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Additionally we are shipping SMOC1 Antibodies (34) and SMOC1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SMOC1 SMOC1 314280  
SMOC1 64093 Q9H4F8
SMOC1 64075 Q8BLY1
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Top SMOC1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SMOC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Top referenced SMOC1 Proteins

  1. Human SMOC1 Protein expressed in Human Cells - ABIN2004985 : Vannahme, Smyth, Miosge, Gösling, Frie, Paulsson, Maurer, Hartmann: Characterization of SMOC-1, a novel modular calcium-binding protein in basement membranes. in The Journal of biological chemistry 2002 (PubMed)

More Proteins for SPARC Related Modular Calcium Binding 1 (SMOC1) Interaction Partners

Human SPARC Related Modular Calcium Binding 1 (SMOC1) interaction partners

  1. IL-17A (show IL17A Proteins) but not IL-22 (show IL22 Proteins) suppresses the replication of hepatitis B virus by inducing the expression of MxA (show MX1 Proteins) and OAS.

  2. SMOC1 provides a link between prenatal hormone exposure and digit ratio.

  3. Homozygosity mapping and subsequent targeted mutation analysis of a locus on 14q24.2 identified homozygous mutations in SMOC1 (SPARC-related modular calcium binding 1) in eight unrelated families with Waardenburg Anophthalmia syndrome.

  4. The present study thus identified SPARC related modular calcium binding 1 as a new cancer-associated protein capable of interacting with tenascin-C (show TNC Proteins) in vitro

  5. these findings indicate that SMOC1/Smoc1 is essential for ocular and limb development in both humans and mice.

  6. Waardenburg anophthalmia syndrome is genetically heterogeneous; a second was locus found on chromosome 14, and mutations in SMOC1 were shown also cause this syndrome.

  7. Analyzed the secretory protein profiles of BMSCs grown in osteogenic medium (OSM (show OSM Proteins)) and identified SPARC-related modular calcium-binding protein 1 (SMOC1), a member of the SPARC (show SPARC Proteins) family, as a regulator of osteoblast differentiation of BMSCs.

  8. isolation of the novel gene SMOC-1 encoding a secreted modular protein containing an EF-hand calcium-binding domain; localization within basement membranes in kidney and skeletal muscle and expression in the zona pellucida surrounding the oocyte

  9. SMOC-1 is of physiological interest because it codes a secreted glycoprotein with five domains, each containing regions homologous to those on other proteins that mediate cell-matrix interactions.

Mouse (Murine) SPARC Related Modular Calcium Binding 1 (SMOC1) interaction partners

  1. SMOC1 is an activin-like kinase antagonist produced by endothelial cells that tips TGF-beta (show TGFB1 Proteins) signalling towards ALK1 (show ACVRL1 Proteins) activation

  2. The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.

  3. these findings indicate that SMOC1/Smoc1 is essential for ocular and limb development in both humans and mice.

  4. SMOC1 and SMOC2 (show SMOC2 Proteins) may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development

  5. expression of SMOC-1 examined in the early embryo day 7, as well as in following embryonic stages on days 12, 14, 16 & 18; broad and organ-specific distribution suggests multifunctional roles of SMOC-1 during mouse embryogenesis

SMOC1 Protein Profile

Protein Summary

This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SMOC1

  • SPARC related modular calcium binding 1 (Smoc1)
  • SPARC related modular calcium binding 1 (SMOC1)
  • SPARC related modular calcium binding 1 (smoc1)
  • 2600002F22Rik protein
  • AI848508 protein
  • OAS protein
  • SMOC-1 protein
  • SMOC1 protein
  • SRG protein
  • XSMOC-1 protein

Protein level used designations for SMOC1

SPARC-related modular calcium binding protein 1 , SPARC-related modular calcium-binding protein 1 , SPARC related modular calcium binding 1 , secreted modular calcium-binding protein 1 , secreted modular calcium-binding 1 , SMOC-1 , SPARC-related gene protein , SPARC-related protein , secreted modular calcium binding protein 1

GENE ID SPECIES
314280 Rattus norvegicus
453002 Pan troglodytes
480373 Canis lupus familiaris
508379 Bos taurus
768688 Gallus gallus
100145733 Xenopus (Silurana) tropicalis
100529120 Danio rerio
64093 Homo sapiens
64075 Mus musculus
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