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SRY (Sex Determining Region Y)-Box 7 Proteins (SOX7)

SOX7 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX7 Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SOX7 83595 Q9BT81
Rat SOX7 SOX7 290317  
SOX7 20680 P40646
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Top SOX7 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,990.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,990.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

SOX7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for SRY (Sex Determining Region Y)-Box 7 (SOX7) Interaction Partners

Human SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. the HMG (show SSRP1 Proteins)-box is a key domain of SOX7 for negatively regulating the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway when functioning as a tumor suppressor in a glioma.

  2. The results provided unequivocal evidence for a novel tumor suppressor role of SOX7 in acute myeloid leukemia (show BCL11A Proteins)

  3. SOX7 plays an important inhibitory role in hepatocarcinogenesis, and might be a novel target for hepatocellular carcinoma therapy.

  4. Ectopic expression of miR (show MLXIP Proteins)-492 led to downregulation of SOX7 protein.

  5. Low SOX7 expression is associated with hepatocellular carcinoma.

  6. The expression of SOX7 correlates with tumor progression as a tumor suppressor, possibly through the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway in ovarian cancers, suggesting that SOX7 may be a promising prognostic marker.

  7. Decreased expression of Sox7 correlates with the upregulation of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway and the poor survival of gastric cancer patients.

  8. miR (show MLXIP Proteins)-184 represents a potential onco-miR (show MLXIP Proteins) and plays an important role in HCC (show FAM126A Proteins) progression by suppressing SOX7 expression

  9. SOX7 acts as a tumor suppressor in breast cancer.

  10. SOX7 is a novel tumor suppressor gene silenced in the majority of NSCLC samples.

Xenopus laevis SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. SOX7 mRNA is localized to the vegetal region of the blastula-stage embryo

  2. SOX7 and SOX18b are essential regulators of cardiogenesis in Xenopus.

  3. Vegetal pole localized Sox7 positively regulates Nodal (Xnr4, Xnr5, and Xnr6) expression, as well as the expression of genes involved in mesodermal (Xmenf, Slug, and Snail) and endodermal (Endodermin and Sox17beta) differentiation.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. combined deletion of Sox7, Sox17 (show SOX17 Proteins), and Sox18 (show SOX18 Proteins) at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 (show SOX17 Proteins) allele largely restores arterial identity

  2. These data indicate that Sox7 is dispensable for both differentiation and maturation of primitive endoderm in an mouse embryonic stem cell model system.

  3. ETV2 (show ETV2 Proteins) directly regulates Sox7, and ETV2 (show ETV2 Proteins) governs endothelial development by regulating transcriptional networks which include Sox7.

  4. Notch and SoxF factors combinatorially regulate Dll4 expression in arteries downstream of VEGF.

  5. Haploinsufficiency of Sox7 or Gata4 (show GATA4 Proteins) is sufficient to produce anterior congenital diaphragmatic hernia in mice.

  6. SOX7 regulates the expression of VE-cadherin (show CDH5 Proteins) in the haemogenic endothelium at the onset of haematopoietic development.

  7. Sox7-sustained expression in the earliest committed hematopoietic precursors promotes the maintenance of their multipotent and self-renewing status.

  8. SOX7 and GATA-4 (show GATA4 Proteins) are competitive activators of Fgf-3 (show FGF3 Proteins) transcription

  9. SOX7 and SOX17 (show SOX17 Proteins) bound specifically to two SOX (show QSOX1 Proteins)-binding sites within the Lama1 (show LAMA1 Proteins) enhancer, and that these SOX (show QSOX1 Proteins)-binding sites functioned synergistically to confer the trans-activation by SOX7 and SOX17 (show SOX17 Proteins)

  10. is required for the induction of Gata-4 (show GATA4 Proteins) and Gata-6 (show GATA6 Proteins), and the interplay among these transcription factors plays a crucial role in parietal endoderm differentiation

Zebrafish SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. Sox7 levels are crucial in arterial specification in conjunction with hey2 (show HEY2 Proteins) and efnb2 (show EFNB2 Proteins) function, with mutants in all three genes displaying shunt formation and an arterial block.

  2. Sox7/18 factors and Notch (show NOTCH1 Proteins) regulate nr2f2 (show NR2F2 Proteins) gene expression during venous differentiation in zebrafish.

  3. Sox7 and Sox18 (show SOX18 Proteins)-mediated transcriptional regulation of Robo4 (show ROBO4 Proteins) is important in the developing embryonic vasculature

  4. Sox7 and sox18 (show SOX18 Proteins) are specifically expressed in the developing vasculature, and simultaneous loss of their function results in a severe loss of the arterial identity of the presumptive aorta.

  5. Sox7 and sox18 (show SOX18 Proteins) play redundant but collectively essential roles in the establishment of proper arteriovenous identity in zebrafish.

  6. Sox7 and Sox18 (show SOX18 Proteins) control arterial-venous identity by regulating Gridlock (show HEY2 Proteins) expression.

SOX7 Protein Profile

Protein Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.

Gene names and symbols associated with SOX7

  • SRY (sex determining region Y)-box 7 (SOX7)
  • SRY (sex determining region Y)-box 7 (Sox7)
  • SRY (sex determining region Y)-box 7 (sox7)
  • SRY-box containing gene 7 (Sox7)
  • SRY-box containing gene 7 (sox7)
  • sox7-A protein
  • xSox7 protein

Protein level used designations for SOX7

transcription factor SOX-7 , SRY-box containing gene 7 , SRY (sex determining region Y)-box 7, xSox7 protein , transcription factor Sox-7 , mSOX7 , SRY (sex determining region Y)-box 7

GENE ID SPECIES
83595 Homo sapiens
290317 Rattus norvegicus
378665 Xenopus laevis
771337 Gallus gallus
486084 Canis lupus familiaris
541256 Bos taurus
100155811 Sus scrofa
20680 Mus musculus
394203 Danio rerio
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