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STE20-Like Kinase Proteins (SLK)

putative serine/threonine protein kinase [RGD, Feb 2006].. Additionally we are shipping SLK Antibodies (72) and SLK Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLK 9748 Q9H2G2
SLK 20874 O54988
Rat SLK SLK 54308 O08815
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Top SLK Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days

SLK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for STE20-Like Kinase (SLK) Interaction Partners

Human STE20-Like Kinase (SLK) interaction partners

  1. SLK (show FYN Proteins) interacts with Tpr and alpha-actinin-4 (show ACTN4 Proteins) in cells, and these protein-protein interactions may control the subcellular localization and the biological activity of SLK (show FYN Proteins).

  2. SLK activated ERMs, together with Galphai, are critical for the correct localization of LGN-NuMA force generator complexes and hence for proper spindle orientation.

  3. The fact that SLK (LOSK) phosphorylates only a minor isoform 1A of p150(Glued (show DCTN1 Proteins)) suggests that transport and microtubule-organizing functions of dynactin (show DCTN1 Proteins) are distinctly divided between the two isoforms

  4. It was shown that lymphocyte-oriented and STE20 kinase were sufficient to restrict ezrin (show EZR Proteins) function to the apical domain. Both kinases were enriched in microvilli and locally activated there.

  5. v-Src (show SRC Proteins)-dependent down-regulation of the Ste20-like kinase SLK through casein kinase II (show CSNK2A1 Proteins).

  6. we show that a novel isoform of SPS1 (show SRM Proteins)-related proline alanine-rich kinase (SPAK (show STK39 Proteins)/STE20 (show STK24 Proteins)) is involved in this inflammatory signaling cascade

  7. Protein kinase (show CDK7 Proteins) LOSK is required for radial microtubule organization and for the proper localization of Golgi complex in various cell types.

  8. Studies define an interaction between Neu (show ERBB2 Proteins) and SLK (show FYN Proteins) signaling in the regulation of cancer cell motility.

Mouse (Murine) STE20-Like Kinase (SLK) interaction partners

  1. activation of SLK by haptotactic signals requires its recruitment to the leading edge by LMO4 (show LMO4 Proteins) in a Src (show SRC Proteins)-dependent manner.

  2. Essential role for the SLK protein kinase in embryogenesis and placental tissue development.

  3. SLK phosphorylates the adhesion adapter protein (show GRB10 Proteins) paxillin (show PXN Proteins) on serine 250. This is required for FAK (show PTK2 Proteins)-dependent focal adhesion dynamics.

  4. Data suggest that podocyte Ste20-like kinase (SLK) overexpression in vivo results in injury and podocyte loss, consistent with the effects of SLK in cultured cells.

  5. Data suggest that Ldb1 (show LDB1 Proteins)/2 function to maintain SLK in an inactive state before its activation.

  6. Associates with microtubules and has a role in Rac1-mediated regulation of actin dynamics during cell adhesion and spreading

  7. SLK is expressed in the neurons and neuroepithelium of the developing embryo in the forebrain, midbrain and hindbrain. Following middle cerebral artery occlusion, SLK neurons are lost and SLK is localized to phagocytic macrophages/microglia.

  8. SLK expression induced in Myf5 (show MYF5 Proteins)- and Pax7 (show PAX7 Proteins)-positive activated satellite cells during regeneration and expression of dominant negative Ste20-like kinase SLK in C2C12 cultures impairs myoblast fusion

  9. Overexpression of active SLK resulted in ectopic spindle assembly and the induction of cell cycle re-entry of Xenopus oocytes, suggesting that SLK is required for progression through G2 upstream of H1 kinase activation

  10. SLK represents a novel focal adhesion disassembly signal

SLK Protein Profile

Protein Summary

putative serine/threonine protein kinase

Gene names and symbols associated with STE20-Like Kinase Proteins (SLK)

  • STE20-like kinase (SLK)
  • Ste20-like kinase (Stlk)
  • STE20-like kinase (Slk)
  • 9A2 protein
  • AV021402 protein
  • AW411554 protein
  • bA16H23.1 protein
  • BcDNA:LD05623 protein
  • CG40293 protein
  • Dmel\\CG40293 protein
  • Etk4 protein
  • LD05623 protein
  • LOSK protein
  • mKIAA0204 protein
  • mSLK protein
  • se20-9 protein
  • SMAK protein
  • Stk2 protein

Protein level used designations for STE20-Like Kinase Proteins (SLK)

STE20-like serine/threonine-protein kinase , CG40293-PA , CG40293-PC , Stlk-PA , Stlk-PC , CTCL tumor antigen se20-9 , Long Ste20-like Kinase , SNF1 (sucrose nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose nonfermenting like kinase , SNF1 sucrose nonfermenting like kinase , STE20-related kinase , STE20-related serine/threonine-protein kinase , Ste20-related serine/threonine kinase , hSLK , serine/threonine-protein kinase 2 , STE20-related kinase SMAK , serine/threonine kinase 2 , serine/threoine kinase

423878 Gallus gallus
486876 Canis lupus familiaris
100156642 Sus scrofa
535342 Bos taurus
3355135 Drosophila melanogaster
9748 Homo sapiens
20874 Mus musculus
54308 Rattus norvegicus
100135621 Cavia porcellus
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