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SWAP Switching B-Cell Complex 70kDa Subunit Proteins (SWAP70)

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. Additionally we are shipping SWAP Switching B-Cell Complex 70kDa Subunit Antibodies (83) and SWAP Switching B-Cell Complex 70kDa Subunit Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SWAP70 20947 Q6A028
Rat SWAP70 SWAP70 293410  
SWAP70 23075 Q9UH65
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Top SWAP Switching B-Cell Complex 70kDa Subunit Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SWAP70 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Interaction Partners

Rhesus Monkey SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) interaction partners

  1. data indicate that SWAP-70 may be involved in regulating motility of trophoblast cells during embryonic implantation and placentation.

Mouse (Murine) SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) interaction partners

  1. These findings reveal an important role of SWAP-70 in the dynamic spatiotemporal regulation of F-actin networks.

  2. Cells expressing the mutant SWAP-70 exhibited faster growth than the parental or wild-type SWAP-70-expressing cells underscoring its role in neoplastic transformation.

  3. SWAP-70 is not required for podosome formation and F-actin turnover in dendritic cells.

  4. SWAP-70 deficiency reveals two pathways that contribute to spontaneous maturation of DCs.

  5. SWAP-70 controls IgE production through regulation of the antagonistic STAT6 and BCL6 occupancy of the germline IgE promoter

  6. A novel function of the F-actin binding and regulatory protein (show TGFB1 Proteins) SWAP-70 in osteoclast biology, is reported.

  7. regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure.

  8. SWAP-70 regulates erythropoiesis by controlling alpha4 integrin.

  9. in a dose-dependent manner, SWAP-70 controls IRF-4 (show IRF4 Proteins) protein expression and thereby regulates the initiation of plasma cell differentiation

  10. SWAP-70-374 can activate some signaling pathways, including the ERK1/2 pathway, to transform MEFs

Human SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) interaction partners

  1. SWAP70 appears to act as a molecular intermediate between vGPCR and endothelial activation.

  2. SWAP70 may be a target of miR (show MLXIP Proteins)-145, and it might have a potential oncogenic function.

  3. Detection of SWAP70 antibodies during the attack period might suggest that SWAP70 is involved in Multiple Sclerosis relapse pathogenesis

  4. The unwinding of the C-terminal alpha-helix could regulate the functions of SWAP-70 at the plasma membrane surface.

  5. findings suggest that regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure

  6. Overexpression of SWAP-70 altered the actin organization and lamellipodial morphology

  7. the binding activity of SWAP-70 to non-muscle F-actin is required for membrane ruffling.

  8. surface expression of SWAP-70 on HIV-1 infected cells as well as PBMCs; SWAP-70 may serve as a marker for T cell differentiation as well as for HIV-1 infection

  9. SWAP-70 may be involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates.

SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Protein Profile

Protein Summary

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

Gene names and symbols associated with SWAP70

  • SWAP switching B-cell complex 70kDa subunit (SWAP70)
  • SWAP switching B-cell complex 70kDa subunit (swap70)
  • SWAP-70 protein (LOC100346427)
  • SWA-70 protein (Swap70)
  • SWAP switching B-cell complex 70 (Swap70)
  • 70kDa protein
  • AV235546 protein
  • HSPC321 protein
  • SWAP-70 protein

Protein level used designations for SWAP70

SWAP switching B-cell complex 70kDa subunit , SWAP-70 protein , switch-associated protein 70-like , SWAP complex protein, 70 kDa , SWAP-70 , switch-associated protein 70 , SWA-70 protein , SWAP complex protein

GENE ID SPECIES
703651 Macaca mulatta
100135363 Xenopus (Silurana) tropicalis
100385137 Callithrix jacchus
100446256 Pongo abelii
100346427 Oryctolagus cuniculus
20947 Mus musculus
293410 Rattus norvegicus
23075 Homo sapiens
485385 Canis lupus familiaris
533720 Bos taurus
423044 Gallus gallus
451020 Pan troglodytes
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