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anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Antibodies

SGCB encodes a member of the sarcoglycan family. Additionally we are shipping Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Proteins (10) and Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SGCB 497757  
SGCB 6443 Q16585
SGCB 24051 P82349
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Top anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry analyzes of Sarcoglycan-β antibody in paraffin-embedded human brain tissue. Western blot analysis of Sarcoglycan-β antibody in extracts from A549 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of Beta-sarcoglycan expression in MCF7 (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-SGCB/SGC Polyclonal Antibody, Unconjugated (ABIN738051) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-SGCB/SGC Polyclonal Antibody, Unconjugated (ABIN738051) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SGCB on formalin-fixed paraffin-embedded human heart (antibody concentration 3 µg/mL).  Detection limit for recombinant GST tagged SGCB is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details

SGCB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Antibodies

  1. Chicken Polyclonal SGCB Primary Antibody for WB - ABIN2781779 : Draviam, Shand, Watkins: The beta-delta-core of sarcoglycan is essential for deposition at the plasma membrane. in Muscle & nerve 2006 (PubMed)

More Antibodies against Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Interaction Partners

Fruit Fly (Drosophila melanogaster) Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

  1. subcellular localization of dScgbeta dramatically changes during mitosis through possible association with tubulin (show TUBB Antibodies); these observations point to a complex role of sarcoglycans in non-muscle tissues.

Human Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

  1. Clinical severity of limb-girdle muscular dystrophy type 2Emay be predicted by SGCB gene mutation and sarcoglycan (show SGCD Antibodies) protein expression.

  2. Defective assembly of sarcoglycan (show SGCD Antibodies) complex in patients with beta-sarcoglycan gene mutations

  3. beta-sarcoglycan and SPATA18 (show SPATA18 Antibodies) may have a role in limb-girdle muscular dystrophy type 2E

  4. While the quantity of beta-sarcoglycan was nearly normal (show EEF1G Antibodies) in the limb girdle muscular dystrophy (LGMD)2E carrier, the levels of dysferlin (show DYSF Antibodies) protein were reduced to 50% of controls in the carriers of LGMD2B (show DYSF Antibodies).

  5. These data suggest that formation of the beta-delta-core may promote the export and deposition of sarcoglycan (show SGCD Antibodies) subcomplexes at the plasma membrane, and therefore identifies a mechanism for sarcoglycan (show SGCD Antibodies) transport.

  6. The limb-girdle muscular dystrophy patients with beta-sarcoglycan deficient LGMD2E do not enable an accurate prediction of the genotype.

Mouse (Murine) Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

  1. serglycin (show SRGN Antibodies) deficient mice exhibited elevated concentrations of serum LDL after feeding high-fat diet for 20 weeks.

  2. serglycin (show SRGN Antibodies) plays a critical role in the maturation of dense-core cytotoxic granules in cytotoxic lymphocytes and the trafficking and storage of perforin (show PRF1 Antibodies) and granzyme B (show Gzmb Antibodies), whereas granzyme A (show GZMA Antibodies) is unaffected

  3. In Sgcb-null mice, severe morphological disruption was present from 4 weeks in both quadriceps and diaphragm, and included conspicuous deposition of extracellular matrix components.

  4. Wild-type mast cells efficiently degraded exogenous or endogenously produced IL-13 (show IL13 Antibodies) upon degranulation,whereas serglycin (show SRGN Antibodies) -/- mast cells completely lacked this ability.

  5. Dopamine storage increased during mast cell maturation from bone marrow precursors, and was dependent on the presence of serglycin (show SRGN Antibodies).

  6. Cells lacking mouse mast cell protease 6 (show TPSB2 Antibodies) exhibited similar defects in apoptosis as observed in serglycin (show SRGN Antibodies)(-/-) cells, indicating that the pro-apoptotic function of serglycin (show SRGN Antibodies) is due to downstream effects of proteases that are complex-bound to serglycin (show SRGN Antibodies)

  7. The PRG-1 (show PTGR1 Antibodies) transcription is initiated at multiple transcription start site and no influence on expression in vivo by Nex1 (show NEUROD6 Antibodies) deficiency.

  8. Aging leads to changes in expression of beta-sarcoglycan in aged affected muscles (diaphragm and limb).

  9. serglycin proteoglycan (show SRGN Antibodies) as a novel player in mast cell apoptosis.

  10. serglycin proteoglycan (show SRGN Antibodies) is dispensable for normal secretion and activity of mast cell proteases in response to peritoneal infection with T. gondii.

Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Antigen Profile

Protein Summary

This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.

Gene names and symbols associated with SGCB

  • Sarcoglycan beta (Scgbeta) antibody
  • SarcoGlycaN (sgn-1) antibody
  • beta-sarcoglycan (AaeL_AAEL006051) antibody
  • beta-sarcoglycan (CpipJ_CPIJ006944) antibody
  • guanylate cyclase 1, soluble, alpha 3 (Gucy1a3) antibody
  • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (sgcb) antibody
  • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB) antibody
  • sarcoglycan, beta (dystrophin-associated glycoprotein) (Sgcb) antibody
  • serglycin (Srgn) antibody
  • 43kDa antibody
  • A3b antibody
  • AI747103 antibody
  • AI844814 antibody
  • beta-sarcoglycan antibody
  • beta-SG antibody
  • CG5657 antibody
  • Dmel\\CG5657 antibody
  • DmSCG-beta antibody
  • dscgbeta antibody
  • Gucy1a1 antibody
  • LGMD2E antibody
  • Prg antibody
  • Prg1 antibody
  • scg-beta antibody
  • Sgc antibody

Protein level used designations for SGCB

sarcoglycan beta , CG5657-PA , Scgbeta-PA , beta-sarcolgycan , beta-sarcoglycan , SarcoGlycaN family member (sgn-1) , GCS-alpha-1 , GCS-alpha-3 , Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase) , Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase) , guanylate cyclase soluble subunit alpha-3 , soluble guanylate cyclase large subunit , 43 kDa dystrophin-associated glycoprotein , 43DAG , beta-SG , beta-sarcoglycan(43kD dystrophin-associated glycoprotein) , limb girdle muscular dystrophy 2E (non-linked families) , sarcoglycan, beta (43kD dystrophin-associated glycoprotein) , gp600 , mastocytoma proteoglycan core protein , proteoglycan 1, secretory granule , proteoglycan, secretory granule , secretory granule proteoglycan core protein

GENE ID SPECIES
41525 Drosophila melanogaster
184162 Caenorhabditis elegans
5567384 Aedes aegypti
6039376 Culex quinquefasciatus
497757 Rattus norvegicus
100127262 Xenopus laevis
422760 Gallus gallus
6443 Homo sapiens
100135674 Sus scrofa
535372 Bos taurus
100009208 Oryctolagus cuniculus
100172796 Pongo abelii
24051 Mus musculus
680229 Rattus norvegicus
19073 Mus musculus
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