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SARDH encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. Additionally we are shipping Sarcosine Dehydrogenase Kits (11) and and many more products for this protein.
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Cow (Bovine) Polyclonal SARDH Primary Antibody for IHC, WB - ABIN2775361
Khan, Rajendiran, Ateeq, Asangani, Athanikar, Yocum, Mehra, Siddiqui, Palapattu, Wei, Michailidis, Sreekumar, Chinnaiyan: The role of sarcosine metabolism in prostate cancer progression. in Neoplasia (New York, N.Y.) 2013
The SNPs rs2797840 and rs2073817 in SARDH may serve as an indicator for the occurrence of neural tube defects in the Chinese Han population, and rs2797840 may also be an indicator for folate content of brain.
Expression of sarcosine metabolism-related proteins differed between ILC (show CCL27 Antibodies) [invasive lobular carcinoma] and IDC (show LMNA Antibodies) [invasive ductal carcinoma].
SARDH and TMEFF2 (show TMEFF2 Antibodies) cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells.
Mutations in the SARDH gene are associated with sarcosinemia.
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described.
sarcosine dehydrogenase, mitochondrial
, sarcosine dehydrogenase
, Sarcosine dehydrogenase
, dimethylglycine dehydrogenase-like 1