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SFMBT1 shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Additionally we are shipping Scm-Like with Four Mbt Domains 1 Proteins (4) and Scm-Like with Four Mbt Domains 1 Kits (3) and many more products for this protein.
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Human Monoclonal SFMBT1 Primary Antibody for WB - ABIN393273
Wu, Trievel, Rice: Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3. in FEBS letters 2007
Show all 5 references for ABIN393273
The malignant brain tumor (MBT (show PRTN3 Antibodies)) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 (show KDM1A Antibodies) demethylase (show MBD2 Antibodies) complex for chromatin association and epithelial-to-mesenchymal transition.
When bound to its gene targets, SFMBT1 recruits its associated proteins and causes chromatin compaction and transcriptional repression
novel mechanisms accounting for SFMBT1-mediated transcription repression and revealed an essential role of Sfmbt1 in regulating MyoD (show MYOD1 Antibodies)-mediated transcriptional silencing
Data identified IGF1 (show IGF1 Antibodies), SLC4A4 (show SLC4A4 Antibodies), WWOX (show WWOX Antibodies), and SFMBT1 as hypertension susceptibility genes by gene based association scan and gene expression analysis.
A segmental copy number loss of the SFMBT1 gene may be involved in the pathological process in some individuals with ventriculomegaly/idiopathic normal pressure hydrocephalus.
The tandem MBT (show PRTN3 Antibodies) repeats form a functional structure required for biological activity of hSFMBT and predict similar properties for other MBT (show PRTN3 Antibodies) domain-containing proteins.
This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition.
Scm-like with four mbt domains 1
, scm-like with four MBT domains protein 1-like
, Scm-related gene containing four mbt domains
, Scm-related gene product containing four mbt domains
, renal ubiquitous protein 1
, scm-like with four MBT domains protein 1
, Scm-related gene containing four mbt domains 1