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SPARC encodes a cysteine-rich acidic matrix-associated protein. Additionally we are shipping SPARC Kits (57) and SPARC Proteins (44) and many more products for this protein.
Showing 10 out of 212 products:
Human Polyclonal SPARC Primary Antibody for EIA, IHC (fro) - ABIN265179
Schäkel, Mayer, Federle, Schmitz, Riethmüller, Rieber: A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. in European journal of immunology 1999
Show all 7 references for ABIN265179
Human Polyclonal SPARC Primary Antibody for WB - ABIN871733
Wewer, Albrechtsen, Fisher, Young, Termine: Osteonectin/SPARC/BM-40 in human decidua and carcinoma, tissues characterized by de novo formation of basement membrane. in The American journal of pathology 1988
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Human Monoclonal SPARC Primary Antibody for WB - ABIN1882278
Bradshaw, Graves, Motamed, Sage: SPARC-null mice exhibit increased adiposity without significant differences in overall body weight. in Proceedings of the National Academy of Sciences of the United States of America 2003
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Human Polyclonal SPARC Primary Antibody for IF (p), IHC (p) - ABIN738141
Chen, Wang, Xi, Xue, He, Zhang, Zhao: SPARC is a key regulator of proliferation, apoptosis and invasion in human ovarian cancer. in PLoS ONE 2012
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Human Polyclonal SPARC Primary Antibody for EIA, WB - ABIN453390
Said, Frierson, Chernauskas, Conaway, Motamed, Theodorescu: The role of SPARC in the TRAMP model of prostate carcinogenesis and progression. in Oncogene 2009
Show all 2 references for ABIN453390
Human Monoclonal SPARC Primary Antibody for ELISA, WB - ABIN562974
Piconese, Costanza, Tripodo, Sangaletti, Musio, Pittoni, Poliani, Burocchi, Passafaro, Gorzanelli, Vitali, Chiodoni, Barnaba, Pedotti, Colombo: The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses. in Journal of autoimmunity 2011
these data identify a contributory role for DNA methylation (show HELLS Antibodies) in regulating sparc expression in zebrafish embryogenesis.
Results establish a role for an ECM (show MMRN1 Antibodies) protein (Sparc) as an important regulator of embryonic haematopoiesis during early development in zebrafish.
Data show that Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear in zebrafish.
Sparc is directly required for normal otolith growth
SPARC levels were not associated with efficacy in patients with MPC. This exploratory analysis does not support making treatment decisions regarding nab-paclitaxel plus gemcitabine or gemcitabine alone in MPC based on SPARC expression.
SPARC is proposed to act as a critical regulator of transglutaminase activity on collagen I with implications for mechanical strength of tissues.
Tumor-produced SPARC and VCAM1 (show VCAM1 Antibodies) are regulators of cancer extravasation.
The results of this study indicated that the loss of p53 (show TP53 Antibodies) by deletion/mutation in the early stages of glioma formation may cooperate with the induction of SPARC to potentiate cancer cell survival and escape from immune surveillance.
This work suggests that SPARC could affect anxiety-related behavior by modulating neuronal activity, and that depression-related behavior is dependent upon the adult expression of SPARC, which affects adult brain function.
SPARC has a significant role in the development of concanavalin A -induced severe liver injury.
SPARC acts as an important mediator of age-related cardiac inflammation by increasing the expression of macrophage M1 markers and decreasing M2 markers.
SPARC inhibits growth factor-induced signaling in both INS-1 beta cells and primary mouse islets, and inhibits IGF-1-induced proliferation of INS-1 beta cells.
Age and SPARC change the extracellular matrix composition of the left ventricle.
findings suggest that SPARC plays a crucial role in the regulation of early B lymphopoiesis.
high SPARC-expression was a significant predictor of poor OS in HPV-negative OPSCC patients using Kaplan-Meier analysis and the log-rank test
We identified five new biomarkers: GDF15 (show GDF15 Antibodies), osteonectin, TRAP5, TWEAK (show TNFSF12 Antibodies), and YKL40 (show CHI3L1 Antibodies) as being promising markers for monitoring bone metastases.
CD90 (show THY1 Antibodies) is upregulated in gastric cancer and inhibits gastric cancer cell apoptosis by modulating the expression level of SPARC protein.
SPARC might be an unfavorable indicator in patients with pancreatic cancer, especially in the stroma.[Review]
tracheal aspirate SPARC levels predicted development of bronchopulmonary dysplasia or death.
SPARC is associated with carcinogenesis of oral squamous epithelium.
Studies indicate that SPARC (secreted protein acidic and rich in cysteine) gene is involved in the development and progression of pancreatic ductal adenocarcinoma (PDAC).
MLKL upregulation in SPARC overexpressed cells treated with Ara (show FOXC1 Antibodies)-C, indicates necrosis as a possible cell death process for the SKM-1 cells under these stringent conditions.
up-regulation of SPARC by oxLDL is independent of Runx2 (show RUNX2 Antibodies), and it may be mediated by other transcription factors
findings indicate that secreted protein acidic cysteine-rich (SPARC) is intricately regulated by pro-angiogenic and other growth factors together with components of the extracellular matrix during the follicle-luteal transition
This study reports the temporal changes in vascular endothelial growth factor A (VEGFA (show VEGFA Antibodies)), fibroblast growth factor 2 (FGF2 (show FGF2 Antibodies)) and osteonectin during the follicular-luteal transition and corpus luteum development in the cow.
data suggest that SPARC might modulate angiogenesis during wound healing in the horse, which could protect against the disproportionate fibroplasia commonly afflicting limb wounds and leading to the development of exuberant granulation tissue
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion.
, basement-membrane protein 40
, secreted protein acidic and rich in cysteine
, cysteine-rich protein
, Secreted acidic cystein-rich glycoprotein (osteonectin)
, secreted acidic cysteine rich glycoprotein