Selectin L Proteins (SELL)

SELL encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. Additionally we are shipping L-Selectin Antibodies (709) and L-Selectin Kits (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SELL 6402 P14151
SELL 29259  
Mouse SELL SELL 20343 P18337
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Top L-Selectin Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Chemical rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Human Cells Chemical Fc Tag,His tag 100 μg Log in to see 20 to 21 Days
$250.80
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HOST_Mammalian Cells Chemical His tag   50 μg Log in to see 4 Days
$203.50
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HOST_Human Cells Chemical His tag 100 μg Log in to see 20 to 21 Days
$250.80
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HOST_Wheat germ Chemical GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Primates His tag   1 mg Log in to see 60 to 71 Days
$2,777.50
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Yeast Pongo pygmaeus His tag   1 mg Log in to see 60 to 71 Days
$2,777.50
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Yeast Pan troglodytes His tag   1 mg Log in to see 60 to 71 Days
$2,777.50
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Yeast Macaca mulatta His tag   1 mg Log in to see 60 to 71 Days
$2,777.50
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,777.50
Details

SELL Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)

More Proteins for Selectin L (SELL) Interaction Partners

Human Selectin L (SELL) interaction partners

  1. Here, we further developed and applied this method to express and purify the entire extracellular region of CD62L. This resulted in excess (show RCC1 Proteins) of 20 mg/L yield of recombinant CD62L. In an attempt to understand the different expression levels among four similar CD62L constructs that differ primarily in signal sequences, we calculated the presence of potential RNA pseudoknots in their signal sequences

  2. identified CD62L as a marker of a distinct NKT (show SLC22A6 Proteins) subset endowed with high proliferative potential and have developed artificial antigen-presenting cells that generate CD62L-enriched NKTs for effective cancer immunotherapy

  3. The -642C>T and 725C>T SELL polymorphisms are protective factors against acute coronary syndrome. SELL gene expression was increased in ACS patients.

  4. CD62L downregulation due to unconstrained HIV-1 replication may have important consequences for T-cell circulation and function and for HIV-1 disease progression

  5. found a higher frequency of LIN1 (show CD2BP2 Proteins)(-) CCR3 (show CCR3 Proteins)(+) eosinophils, and decreased expression of CD23 (show FCER2 Proteins) and CD62L receptors in eosinophils of AD patients

  6. Indian patients with primary Sjogren's syndrome have higher salivary sL-selectin and IL-7 (show IL7 Proteins) levels than healthy controls

  7. While total surface expression of CD11b (show ITGAM Proteins) and L-selectin on neutrophils was largely unaffected

  8. Data show that both mucin16 (MUC16 (show MUC16 Proteins)) and podocalyxin (PODXL (show PODXL Proteins))-E-selectin (show SELE Proteins)-mediated interactions are mechanically stronger than like L-selectin interactions at the single-molecule level.

  9. These data confirm the expression of CD62L on urothelial carcinoma cells and suggest that CD62L may serve as biomarker to predict the presence of or risk for developing metastatic disease in patients with bladder cancer.

  10. freeze and thaw of murine and human Tregs is associated with reduced expression of L-selectin (CD62L), which was previously established to be an important factor that contributes to the in vivo protective effects of Tregs

Cow (Bovine) Selectin L (SELL) interaction partners

  1. Five single nucleotide polymorphisms (SNPs) from different exons in selectin SELP (show SELP Proteins), two in selectin SELL and one in selectin SELE (show SELE Proteins) were taken forward to genotyping in 337 Holstein Friesian heifers using PCR-RFLP.

  2. gammadelta T cells, the main recirculating subset in both afferent and efferent lymph, have high levels of CD62L cell surface expression.

  3. demonstrate the existence of central memory T cells (Tcm) in cattle and suggest that CD62L may serve as a marker to monitor Tcm in infections and vaccine development studies in ruminant.

  4. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA Proteins), CD44 (show CD44 Proteins), and CD62L expression on peripheral blood T-cell subsets from M. bovis-infected cattle

  5. intramammarily administered lipopolysaccharides seem to play an important role in modulating L-selectin and beta2 integrin expression on circulating bovine polymorphonuclear leukocytes

  6. results indicate that glucocorticoid-induced suppression of L-selectin is likely mediated by direct effects of glucocorticoid receptor (show NR3C1 Proteins) activation on intracellular reservoirs of L-selectin mRNA and protein, predominantly in blood neutrophils.

Mouse (Murine) Selectin L (SELL) interaction partners

  1. CD8 (show CD8A Proteins)(+) T-cells mediate ischemia reperfusion injury in a fatty liver through L-selectin.

  2. L-selectin is transported constitutively by the AP-1 (show JUN Proteins) complex, leading to the formation of a trans-Golgi network reserve pool; phosphorylation of the L-selectin tail blocks AP-1 (show JUN Proteins)-dependent retrograde transport of L-selectin

  3. freeze and thaw of murine and human Tregs is associated with reduced expression of L-selectin (CD62L), which was previously established to be an important factor that contributes to the in vivo protective effects of Tregs

  4. endothelial colony-forming cells interact with activated neutrophils via PSGL-1 (show SELPLG Proteins) and L-selectin

  5. These data indicate that L-selectin plays a major role in the development of C protein induced polymyositis, whereas ICAM-1 (show ICAM1 Proteins) plays a lesser role, if any.

  6. These results put into question the utility of CD62L as a predictive biomarker for the efficacy of ex vivo-expanded T cells after ACT in lymphopenic conditions.

  7. The PSGL-1 (show SELPLG Proteins)-L-selectin complex-induced signaling effects on neutrophil slow rolling and recruitment in vivo demonstrate the functional importance of this pathway.

  8. L-selectin-dependent signalling - exploring the different signals that potentially arise from distinct phases of the multi-step adhesion cascade and the contribution of known binding partners of L-selectin in this respon

  9. CD62L marks a mature natural killer (NK) cell subset by affecting the magnitude of the local NK cell response to adenovirus infection in the liver.

  10. Data indicate that naive lung CD4 (show CD4 Proteins) cells supply the draining lymph nodes through a CD62L-independent, CCR7 (show CCR7 Proteins)-dependent pathway.

L-Selectin (SELL) Protein Profile

Protein Summary

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with Selectin L Proteins (SELL)

  • selectin L (SELL)
  • selectin L (Sell)
  • selectin, lymphocyte (Sell)
  • A.11 protein
  • AI528707 protein
  • CD62L protein
  • L-selectin protein
  • LAM1 protein
  • LECAM-1 protein
  • LECAM1 protein
  • LEU8 protein
  • Lnhr protein
  • LSEL protein
  • Ly-22 protein
  • Ly-m22 protein
  • Lyam-1 protein
  • Lyam1 protein
  • PLNHR protein
  • SELE protein
  • TQ1 protein

Protein level used designations for Selectin L Proteins (SELL)

CD62 antigen-like family member L , L-selectin , gp90-MEL , leukocyte surface antigen Leu-8 , leukocyte-endothelial cell adhesion molecule 1 , lymph node homing receptor , lymphocyte adhesion molecule 1 , pln homing receptor , LAM-1 , LECAM1 , leukocyte adhesion molecule 1 , ly-22 , lymphocyte antigen 22 , lymphocyte surface MEL-14 antigen , selectin, lymphocyte , selectin L (lymphocyte adhesion molecule 1) , selectin E (endothelial adhesion molecule 1)

GENE ID SPECIES
6402 Homo sapiens
29259 Rattus norvegicus
100009204 Oryctolagus cuniculus
100716722 Cavia porcellus
100127147 Sus scrofa
281485 Bos taurus
480080 Canis lupus familiaris
101102077 Ovis aries
701419 Macaca mulatta
450191 Pan troglodytes
20343 Mus musculus
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