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L-Selectin Products

(Selectin L (SELL))

Categories

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].

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Featured L-Selectin Categories

L-Selectin Antibodies

High quality antibodies with extensive validation data.

L-Selectin ELISA Kits

Reliable ELISA kits for a wide range of species.

L-Selectin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended L-Selectin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Validations
  • (1)
  • (7)
Cat. No. ABIN736716
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN3022264
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (4)
  • (4)
Cat. No. ABIN192344
Quantity 100 tests
Datasheet Datasheet

Recommended L-Selectin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959337
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959336
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959338
Quantity 96 tests
Datasheet Datasheet

Recommended L-Selectin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275559
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275556
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125012
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our L-Selectin products

Waaler, Mygland, Tveita, Strand, Solberg, Olsen, Aizenshtadt, Fauskanger, Lund, Brinch, Lycke, Dybing, Nygaard, Bøe, Heintz, Hovig, Hammarström, Corthay, Krauss: "Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models." in: Communications biology, Vol. 3, Issue 1, pp. 196, (2020) (PubMed).

Barth, Marwick, Heeb, Gale, Rossi, Dransfield: "Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 9, pp. 2602-2611, (2018) (PubMed).

Lougaris, Patrizi, Baronio, Tabellini, Tampella, Damiati, Frede, van der Meer, Fliegauf, Grimbacher, Parolini, Plebani: "NFKB1 regulates human NK cell maturation and effector functions." in: Clinical immunology (Orlando, Fla.), Vol. 175, pp. 99-108, (2017) (PubMed).

Pedroza-Pacheco, Shah, Domogala, Luevano, Blundell, Jackson, Thrasher, Madrigal, Saudemont: "Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation." in: Scientific reports, Vol. 6, pp. 22097, (2017) (PubMed).

Cesana, Santoni de Sio, Rudilosso, Gallina, Calabria, Beretta, Merelli, Bruzzesi, Passerini, Nozza, Vicenzi, Poli, Gregori, Tambussi, Montini: "HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells." in: Nature communications, Vol. 8, Issue 1, pp. 498, (2017) (PubMed).

Vries, Wagenaar, Verbruggen, Molin, Post: "CXCL1 promotes arteriogenesis through enhanced monocyte recruitment into the peri-collateral space." in: Angiogenesis, (2015) (PubMed).

Leoni, Gripentrog, Lord, Riesselman, Sumagin, Parkos, Nusrat, Jesaitis: "Human neutrophil formyl peptide receptor phosphorylation and the mucosal inflammatory response." in: Journal of leukocyte biology, Vol. 97, Issue 1, pp. 87-101, (2015) (PubMed).

Chang, Eckert, Ali, Riazifar, Pone, Liu, Zhao: "Facile supermolecular aptamer inhibitors of L-selectin." in: PLoS ONE, Vol. 10, Issue 3, pp. e0123034, (2015) (PubMed).

Vassena, Giuliani, Koppensteiner, Bolduan, Schindler, Doria: "HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes." in: Journal of virology, Vol. 89, Issue 10, pp. 5687-700, (2015) (PubMed).

Liu, Hu, Chan, Wat, Lau, Hon, Fung, Leung, Hui, Lam, Wong: "Anti-inflammatory and anti-allergic activities of Pentaherb formula, Moutan Cortex (Danpi) and gallic acid." in: Molecules (Basel, Switzerland), Vol. 18, Issue 3, pp. 2483-500, (2013) (PubMed).

Synonyms and alternative names related to L-Selectin

selectin L (SELL), selectin L (Sell), selectin, lymphocyte (Sell), A.11, AI528707, CD62L, L-selectin, LAM1, LECAM-1, LECAM1, LEU8, LNHR, Lnhr, LSEL, Ly-22, Ly-m22, Lyam-1, LYAM1, Lyam1, PLNHR, SELE, TQ1

Protein level used designations for L-Selectin

  • CD62 antigen-like family member L
  • L-selectin
  • gp90-MEL
  • leukocyte surface antigen Leu-8
  • leukocyte-endothelial cell adhesion molecule 1
  • lymph node homing receptor
  • lymphocyte adhesion molecule 1
  • pln homing receptor
  • LAM-1
  • LECAM1
  • leukocyte adhesion molecule 1
  • ly-22
  • lymphocyte antigen 22
  • lymphocyte surface MEL-14 antigen
  • selectin, lymphocyte
  • selectin L (lymphocyte adhesion molecule 1)
  • selectin E (endothelial adhesion molecule 1)
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