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anti-Selenocysteine Lyase (SCLY) Antibodies

Selenocysteine lyase (SCLY\\\\; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Selenocysteine Lyase Proteins (12) and Selenocysteine Lyase Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCLY 51540 Q96I15
SCLY 50880 Q9JLI6
SCLY 363285 Q68FT9
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Top anti-Selenocysteine Lyase Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Anti-SCLY antibody, Western blotting Lane 1: U87 Cell Lysate Lane 2: HELA Cell Lysate Lane 3: 293T Cell Lysate Lane 4: MCF-7 Cell Lysate Lane 5: COLO320 Cell Lysate Lane 6:  Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB SCLY Antibody (N-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SCLY antibody detected the SCLY protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IP, WB SCLY MaxPab rabbit polyclonal antibody. Western Blot analysis of SCLY expression in human liver. SCLY MaxPab rabbit polyclonal antibody. Western Blot analysis of SCLY expression in HeLa. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated IP, ELISA Detection limit for recombinant GST tagged SCLY is 0.3 ng/ml as a capture antibody. Immunoprecipitation of SCLY transfected lysate using anti-SCLY monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with SCLY monoclonal antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated ELISA, WB SCLY polyclonal antibody (A01), Lot # 051220JC01 Western Blot analysis of SCLY expression in 293 . Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB SCLY MaxPab rabbit polyclonal antibody. Western Blot analysis of SCLY expression in human liver. SCLY MaxPab rabbit polyclonal antibody. Western Blot analysis of SCLY expression in HeLa. 100 μg Log in to see 9 Days
$418.57
Details

SCLY Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


Rat (Rattus)


More Antibodies against Selenocysteine Lyase Interaction Partners

Human Selenocysteine Lyase (SCLY) interaction partners

  1. Concurrent exogenous expression of three transcription factors, GATA1 (show GATA1 Antibodies), FLI1 (show FLI1 Antibodies) and TAL1 (show TAL1 Antibodies), enables large-scale production of megakaryocytes from human pluripotent stem cells.

  2. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  3. a successful induction of gamma-globin (show HBG1 Antibodies) includes a reduction in BCL11A (show BCL11A Antibodies), KLF1 (show KLF1 Antibodies) and TAL1 (show TAL1 Antibodies) expression.

  4. SCL (show KRT7 Antibodies)-mediated transcriptional network enhances megakaryocytic specification of human embryonic stem cells.

  5. These results indicate that KLF1 (show KLF1 Antibodies) plays a role in facilitating and/or stabilizing GATA-1 (show GATA1 Antibodies) and TAL1 (show TAL1 Antibodies) occupancy in the erythroid genes, contributing to the generation of active chromatin structure such as histone acetylation and chromatin looping

  6. Scl (show KRT7 Antibodies) binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence.

  7. SCL/TAL1 (show TAL1 Antibodies) is located in the up-stream of MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) pathway and partially regulates hematopoiesis by modulating the phosphorylation level of the key proteins in MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) pathway.

  8. study found that heterozygous somatic mutations are acquired that introduce binding motifs for the MYB (show MYB Antibodies) transcription factor in a precise noncoding site, which creates a super-enhancer upstream of the TAL1 (show TAL1 Antibodies) oncogene (show RAB1A Antibodies); MYB (show MYB Antibodies) binds to this new site

  9. The results indicate that TAL1 plays a critical role in chromatin loop formation between the gamma-globin genes and locus control region, which is a critical step for the transcription of the gamma-globin genes.

  10. SIL (show PMEL Antibodies)-TAL1 (show TAL1 Antibodies) rearrangement identifies a distinct subtype with inferior outcome which could allow for individual therapeutic stratification for T-ALL patients.

Mouse (Murine) Selenocysteine Lyase (SCLY) interaction partners

  1. This study showed that Male mice lacking two key genes involved in Se metabolism (Scly(-/-)Sepp1 (show SEPP1 Antibodies)(-/-) mice), selenoprotein P (Sepp1 (show SEPP1 Antibodies)) and Sec lyase (Scly), develop severe neurological dysfunction, neurodegeneration, and audiogenic seizures.

  2. our findings unveil a new metabolic role for Reg3beta in protein nitration and a new biosynthesis control of GPX1 (show GPX1 Antibodies) by a completely "unrelated" regenerating protein, Reg3beta, via transcriptional activation of Scly

  3. These findings provide the first in vivo evidence that Scly and Sepp1 (show SEPP1 Antibodies) work cooperatively to maintain selenoprotein function in the mammalian brain.

  4. The results suggested a dependence of glucose and lipid homeostasis on selenocysteine lyase activity. These findings connect Se and energy metabolism and demonstrate for the first time a unique physiological role of selenocysteine lyase.

  5. Scly knockout mice do not display neurological dysfunction comparable to Sepp1 (show SEPP1 Antibodies) knockout mice.

Selenocysteine Lyase (SCLY) Antigen Profile

Protein Summary

Selenocysteine lyase (SCLY\; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000

Gene names and symbols associated with SCLY

  • cysteine desulfurase (nifS) antibody
  • selenocysteine lyase (csdB) antibody
  • selenocysteine lyase (EUBELI_20129) antibody
  • Selenocysteine lyase (Deima_1599) antibody
  • selenocysteine lyase (SCLY) antibody
  • selenocysteine lyase (Scly) antibody
  • selenocysteine lyase (scly) antibody
  • T-cell acute lymphocytic leukemia 1 (TAL1) antibody
  • 9830169H08 antibody
  • A930015N15Rik antibody
  • bHLHa17 antibody
  • hSCL antibody
  • SCL antibody
  • Scly1 antibody
  • Scly2 antibody
  • tal-1 antibody
  • TCL5 antibody

Protein level used designations for SCLY

selenocysteine lyase , Selenocysteine lyase , mSCL , selenocysteine lyase; Selenocysteine reductase , selenocysteine reductase , T-cell acute lymphocytic leukemia protein 1 , T-cell leukemia/lymphoma protein 5 , class A basic helix-loop-helix protein 17 , stem cell protein , tal-1 product

GENE ID SPECIES
1209031 Coxiella burnetii RSA 493
3103136 Methylococcus capsulatus str. Bath
3191895 Francisella tularensis subsp. tularensis SCHU S4
4200277 Francisella tularensis subsp. tularensis FSC198
4306356 Francisella tularensis subsp. holarctica OSU18
7962638 Eubacterium eligens ATCC 27750
10150952 Deinococcus maricopensis DSM 21211
51540 Homo sapiens
50880 Mus musculus
363285 Rattus norvegicus
790815 Bos taurus
447624 Xenopus laevis
6886 Homo sapiens
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