Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
SEPP1 encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. Additionally we are shipping Selenoprotein P Antibodies (42) and Selenoprotein P Proteins (8) and many more products for this protein.
Showing 6 out of 24 products:
Human SEPP1 ELISA Kit for Sandwich ELISA - ABIN850939
Asci, Surmeli-Onay, Erkekoglu, Yigit, Yurdakok, Kocer-Gumusel: Oxidant and antioxidant status in neonatal proven and clinical sepsis in relation to selenium status. in Pediatrics international : official journal of the Japan Pediatric Society 2015
Show all 3 Pubmed References
Human SEPP1 ELISA Kit for Sandwich ELISA - ABIN456387
Ghattas, Mehanna, Mesbah, Abo-Elmatty: Relaxin-3 is associated with metabolic syndrome and its component traits in women. in Clinical biochemistry 2013
We have demonstrated a significant decrease in circulating SeP (show PLXNB1 ELISA Kits) levels according to MetS status in patients with documented cardiovascular disease.
Results indicate a diversity of RNA elements conducting multiple occurrences of UGA redefinition to control the synthesis of full-length and truncated selenoprotein P (SELENOP) isoforms.
Study suggests the 3' UTR (show UTS2R ELISA Kits) structural elements (SECIS) in Sepp1 functions with site specificity and further illustrates how mRNA processing may produce transcripts with altered coding potential to produce diversity in selenoprotein isoforms.
Inc (show PLXNB1 ELISA Kits)reased amounts of circulating SeP predicted the ineffectiveness of training on endurance capacity in humans.
Results indicate that the 2 genetic variants of rs7579 and rs230813 in SEPP1 may not play a role in the pathogenesis of preeclampsia in Chinese Han Women.
erum microRNA-7 and selenoprotein P appear to be potential non-invasive diagnostic markers for hepatocellular carcinoma. Moreover, the results suggest that selenium could be used as an anticancer therapy for hepatocellular carcinoma by affecting both microRNA-7 and selenoprotein P
The selenium levels in the tissues were correlated to the genotype of the SELENOP selenium carrier protein, but not to other proteins whose levels have been reported to be responsive to selenium availability, including GPX1 (show GPX1 ELISA Kits), SELENOF and SBP1 (show MEGF8 ELISA Kits).
GPX1 (show GPX1 ELISA Kits) and SEPP1 Single Nucleotide Polymorphism were not associated with any changes in the expression of related genes. GPX1 (show GPX1 ELISA Kits) was shown to modulate the expression of unrelated target, SEP15 (show SEP15 ELISA Kits), upon Se supplementation, both alone and in combination with SEPP1.
Data show that the cell proliferative ability was inhibited in the cells overexpressing selenoprotein P, plasma 1 (SEPP1), and the colony forming ability of The cell evidently decreased.
Selenoprotein P concentrations are not elevated in women with gestational diabetes mellitus but are associated with BMI and HDL (show HSD11B1 ELISA Kits) cholesterol.
SeP (show EPHX2 ELISA Kits) causes exercise resistance through its muscle receptor low-density lipoprotein receptor-related protein 1 (LRP1 (show LRP1 ELISA Kits)). SeP (show EPHX2 ELISA Kits)-deficient mice showed a 'super-endurance' phenotype after exercise training, as well as enhanced reactive oxygen species production, AMPK (show PRKAA1 ELISA Kits) phosphorylation and Ppargc-1alpha expression in skeletal muscle.
Through correlational analysis, it was determined that the effects of Se-supplement were closely related to SelP expression, inflammatory cytokines, and apoptosis molecule production.
This study showed that Male mice lacking two key genes involved in Se metabolism (Scly (show SCLY ELISA Kits)(-/-)Sepp1(-/-) mice), selenoprotein P (Sepp1) and Sec lyase (Scly (show SCLY ELISA Kits)), develop severe neurological dysfunction, neurodegeneration, and audiogenic seizures.
Results indicate that selenoprotein P (Sepp1) is important for this transport in selenium-replete mice but that glutathione peroxidase-3 (Gpx3 (show GPX3 ELISA Kits)) is not.
Sepp1 haploinsufficiency or mutations that disrupt either the selenium transport or the enzymatic domain of SEPP1 exhibit increased colitis-associated carcinogenesis via increased genomic instability and promotion of a protumorigenic microenvironment
plasma Sepp1(UF) and small selenium-containing proteins are filtered by the glomerulus and taken up by PCT (show UROD ELISA Kits) cells via megalin (show LRP2 ELISA Kits)-mediated endocytosis.
Tandem Sepp1-apoER2 (show LRP8 ELISA Kits) interactions supply selenium for maintenance of brain neurons both at the blood-brain barrier and within the brain. Sepp1 inside the blood-brain barrier is taken up by neurons via apoER2 (show LRP8 ELISA Kits), concentrating brain selenium in them.
These findings provide the first in vivo evidence that Scly (show SCLY ELISA Kits) and Sepp1 work cooperatively to maintain selenoprotein function in the mammalian brain.
This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.
, plasma selenoprotein P
, selenoprotein P-like protein