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anti-Sepiapterin Reductase (SPR) Antibodies

SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Additionally we are shipping Sepiapterin Reductase Proteins (17) and Sepiapterin Reductase Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPR 20751  
SPR 29270 P18297
SPR 6697 P35270
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Top anti-Sepiapterin Reductase Antibodies at antibodies-online.com

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Sepiapterin reductase (arrow) in mouse liver tissue lysates (35ug/lane) using Sepiapterin reductase / SPR 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of SPR Antibody (C-term) (ABIN653908) in mouse liver tissue lysates (35 µg/lane). SPR (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SPR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate WB Suggested Anti-SPR  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Hela cell lysate  SPR is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB SPR polyclonal antibody (A01), Lot # 060123JCO1 Western Blot analysis of SPR expression in A-431 . SPR polyclonal antibody (A01), Lot # 060814QCS1. Western Blot analysis of SPR expression in Jurkat. 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of SPR expression in transfected 293T cell line by SPR MaxPab polyclonal antibody.Lane1:SPR transfected lysate(28.71 KDa).Lane2:Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Mouse Un-conjugated FACS, IF, WB Anti-SPR mouse monoclonal antibody (ABIN2453684) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR (RC205679). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR. 100 μL Log in to see 2 to 3 Days
$423.50
Details

SPR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Top referenced anti-Sepiapterin Reductase Antibodies

  1. Human Polyclonal SPR Primary Antibody for EIA, WB - ABIN954723 : Leu-Semenescu, Arnulf, Decaix, Moussa, Clot, Boniol, Touitou, Levy, Vidailhet, Roze: Sleep and rhythm consequences of a genetically induced loss of serotonin. in Sleep 2010 (PubMed)
    Show all 3 references for ABIN954723

  2. Human Polyclonal SPR Primary Antibody for WB - ABIN520456 : Lange, Geerts, Feith, Mocz, Koster, Bachmann: Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation. in Journal of molecular biology 2014 (PubMed)

  3. Human Polyclonal SPR Primary Antibody for ELISA, WB - ABIN562987 : Balasubramanian, Deng, Doudney, Hampton, Kennedy: Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line. in Neuropharmacology 2015 (PubMed)

  4. Human Polyclonal SPR Primary Antibody for WB - ABIN653908 : Maddens, Ghesquière, Vanholder, Demon, Vanmassenhove, Gevaert, Meyer: Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury. in Molecular & cellular proteomics : MCP 2012 (PubMed)

More Antibodies against Sepiapterin Reductase Interaction Partners

Mouse (Murine) Sepiapterin Reductase (SPR) interaction partners

  1. SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms

  2. biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21 (show D4S234E Antibodies)

  3. These data suggest an essential role of SPR in the biosynthesis of BH4, and that the SPR gene could be a candidate gene for PARK3.

Human Sepiapterin Reductase (SPR) interaction partners

  1. These findings reveal important insight into the molecular mechanisms of the NK1R (show TACR1 Antibodies) complex as a critical component in a model of pediatric liver cancer and may support the development of novel therapeutic interventions for hepatoblastoma

  2. Neuropeptide signaling through neurokinin-1 (show TAC1 Antibodies) and neurokinin-2 (show TAC1 Antibodies) receptors augments antigen presentation by human dendritic cells

  3. Inhibition of CaV2.3 (show CACNA1E Antibodies) channels by NK1 (show CD160 Antibodies) receptors is sensitive to membrane cholesterol but insensitive to caveolin-1 (show CAV1 Antibodies).

  4. We earlier presented evidence for a physical interaction between ODC (show ODC1 Antibodies) and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC (show ODC1 Antibodies) enzyme activity and impeded Neuroblastoma (show ARHGEF16 Antibodies) cell proliferation.

  5. NK-1 (show CD160 Antibodies) activation could enhance EGFR (show EGFR Antibodies) expression and phosphorylation, and then activate EGFR (show EGFR Antibodies) related Erk/MAPK (show MAPK1 Antibodies) and Akt (show AKT1 Antibodies) pathway.

  6. The single nucleotide polymorphisms in the TACR1 (show TACR1 Antibodies) gene are associated with sex differences in postoperative nausea and vomiting.

  7. Results show the existence of a relevant alteration in NK-1R (show TACR1 Antibodies) expression in bipolar disorder patients and further suggest Substance P (show TAC1 Antibodies) involvement in BD.

  8. Immunohistochemical NK-1R (show TACR1 Antibodies) and pEGFR positivity with VDR (show CYP27B1 Antibodies) negativity can be used to identify areas of sporadic colorectal neoplasia.

  9. Hepatoblastoma cells predominantly expressed the truncated splice variant of NK1R (show TACR1 Antibodies).

  10. Findings indicate a role of the TACR1 (show TACR1 Antibodies) gene in the development of sicca syndrome in subjects affected with fibromyalgia.

Cow (Bovine) Sepiapterin Reductase (SPR) interaction partners

  1. this study demonstrates an important role of endothelial SPR in modulating tetrahydrobiopterin and nitric oxide bioavailability

Sepiapterin Reductase (SPR) Antigen Profile

Protein Summary

This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Gene names and symbols associated with SPR

  • Sepiapterin reductase (Sptr) antibody
  • sepiapterin reductase (sprE) antibody
  • sepiapterin reductase (CpipJ_CPIJ000511) antibody
  • sepiapterin reductase (sr) antibody
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (spr) antibody
  • Sepiapterin reductase (spre) antibody
  • sepiapterin reductase (Spr) antibody
  • sepiapterin reductase (spre) antibody
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (Spr) antibody
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR) antibody
  • tachykinin receptor 1 (TACR1) antibody
  • tachykinin receptor 1 (Tacr1) antibody
  • AA409688 antibody
  • CG12117 antibody
  • DDBDRAFT_0188686 antibody
  • DDBDRAFT_0191275 antibody
  • DDB_0188686 antibody
  • DDB_0191275 antibody
  • Dmel\\CG12117 antibody
  • ENSMUSG00000071345 antibody
  • Gm10328 antibody
  • NK1R antibody
  • NKIR antibody
  • SDR38C1 antibody
  • SPR antibody
  • sptr antibody
  • SR antibody
  • Tac1r antibody
  • xspr antibody

Protein level used designations for SPR

sepiapterin reductase , CG12117-PA , Sptr-PA , Sepiapterin reductase , short chain dehydrogenase/reductase family 38C, member 1 , 7,8-dihydrobiopterin:NADP+ oxidoreductase , NK-1 receptor , NK-1R , substance-P receptor , tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor) , SPR , neurokinin 1 receptor , substance p receptor

GENE ID SPECIES
31781 Drosophila melanogaster
1793292 Rhodopirellula baltica SH 1
6031370 Culex quinquefasciatus
8627440 Dictyostelium discoideum AX4
100145068 Xenopus (Silurana) tropicalis
100195245 Salmo salar
100379197 Bombyx mori
100528817 Ictalurus punctatus
20751 Mus musculus
29270 Rattus norvegicus
6697 Homo sapiens
533836 Bos taurus
380273 Xenopus laevis
6869 Homo sapiens
24807 Rattus norvegicus
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