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anti-Septin 4 (SEPT4) Antibodies

SEPT4 is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Additionally we are shipping Septin 4 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SEPT4 287606  
SEPT4 5414 O43236
SEPT4 18952 P28661
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Top anti-Septin 4 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB AP22419PU-N ARTS antibody staining of Human Heart lysate at 1µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated EIA, WB AP22420PU-N ARTS antibody staining of Human Cerebellum lysate at 0.5 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB   400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Human Lung, Respiratory Epithelium (formalin-fixed, paraffin-embedded) stained with SEPT4 antibody ABIN214473 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with SEPT4 antibody ABIN214473 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details

SEPT4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
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Mouse (Murine) ,
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Top referenced anti-Septin 4 Antibodies

  1. Cow (Bovine) Polyclonal SEPT4 Primary Antibody for EIA, WB - ABIN569627 : Lhuillier, Rode, Escalier, Lorès, Dirami, Bienvenu, Gacon, Dulioust, Touré: Absence of annulus in human asthenozoospermia: case report. in Human reproduction (Oxford, England) 2009 (PubMed)

  2. Human Polyclonal SEPT4 Primary Antibody for FACS, IHC (p) - ABIN1944842 : Garcia, Rodrigues, de Oliveira Neto, de Araújo, Polikarpov, Tanaka, Tanaka, Garratt: The stability and aggregation properties of the GTPase domain from human SEPT4. in Biochimica et biophysica acta 2008 (PubMed)

  3. Dog (Canine) Polyclonal SEPT4 Primary Antibody for IHC, WB - ABIN2792123 : Elhasid, Sahar, Merling, Zivony, Rotem, Ben-Arush, Izraeli, Bercovich, Larisch: Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients. in Oncogene 2004 (PubMed)

More Antibodies against Septin 4 Interaction Partners

Human Septin 4 (SEPT4) interaction partners

  1. The data suggest that Sept4_i1 induces hepatic stellate cell apoptosis by inhibiting Akt (show AKT1 Antibodies) and Bcl-2 (show BCL2 Antibodies) expression and up-regulating PPAR-gamma (show PPARG Antibodies) expression.

  2. Bradeion/SEPT4 transcript levels are significantly increased in patients with transitional cell bladder cancer.We hypothesize that Bradeion is directly involved in bladder cancer pathogenesis with the highest expression at early cancer stages.

  3. Identification of a novel anti-apoptotic E3 ubiquitin ligase (show MUL1 Antibodies) that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC (show DIABLO Antibodies), HtrA2 (show HTRA2 Antibodies), and ARTS.

  4. these data suggests a tumor suppressor role of SEPT4_i1 in HCC (show FAM126A Antibodies) through regulating hepatocellular carcinoma cell apoptosis.

  5. SEPT4 is a Notch (show NOTCH1 Antibodies) target gene.

  6. The expression of SEPT4 is significantly decreased in the ejaculated sperm of idiopathic asthenozoospermia patients.

  7. role of Bradeion in colorectal neoplasms

  8. Sept4 is involved in the formation of cytoplasmic inclusions as well as induction of cell death in alpha-synuclein (show SNCA Antibodies)-associated neurodegenerative disorders.

  9. Data suggest that ARTS induces apoptosis by antagonizing IAPs, including XIAP (show XIAP Antibodies).

  10. SEPT8 (show SEPT8 Antibodies) and SEPT4 are localized surrounding alpha-granules. Activation of platelets by agonists resulted in the translocation of SEPT4 and SEPT8 (show SEPT8 Antibodies) to the platelet surface indicating a possible functional role of these proteins in platelet granular secretion

Mouse (Murine) Septin 4 (SEPT4) interaction partners

  1. Adenovirus-Sept4 can attenuate the development of liver fibrosis induced by S. japonicum through apoptosis.

  2. The inhibition of the expression of the SEPT4 by praziquantel might be due to alleviation of the inflammatory response at the chronic and advanced stage of S. japonicum infection.

  3. The hypothetical pathogenicity by the chronic overload of SEPT4 alone, if any, is insufficient to trigger neurodegenerative process in the mouse brain.

  4. Sept4/ARTS(-/-) mice display marked improvement in wound healing and regeneration of hair follicles.

  5. Identification of a novel anti-apoptotic E3 ubiquitin ligase (show MUL1 Antibodies) that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC (show DIABLO Antibodies), HtrA2 (show HTRA2 Antibodies), and ARTS.

  6. Report SEPT4/5/7 expression in mouse cochlea and roles in auditory function.

  7. Sept4 and alpha-SMA (show SMN1 Antibodies) may interact together in hepatic stellate cells (HSCs). Sept4 seems to be involved in the formation of inflammatory granulomata and subsequent liver fibrosis by regulating HSCs activation.

  8. ARTS (Septin 4) promotes apoptosis mainly through binding and antagonizing XIAP (show XIAP Antibodies).

  9. Loss of Sept4 is associated with myofibroblastic transformation of hepatic stellate cells and results in liver fibrosis.

  10. Findings suggest that Sept4-null mice develop malignancies due to increased resistance of their HSPCs to apoptosis.

Septin 4 (SEPT4) Antigen Profile

Protein Summary

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct\; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Gene names and symbols associated with anti-Septin 4 (SEPT4) Antibodies

  • septin 4 (Sept4) antibody
  • septin 4 (SEPT4) antibody
  • septin 4 (PAAG_00317) antibody
  • septin 4 (PGTG_11810) antibody
  • septin 4 (LOC100354312) antibody
  • ARTS antibody
  • Bh5 antibody
  • BRADEION antibody
  • CE5B3 antibody
  • DKFZp459F1329 antibody
  • DKFZp459I029 antibody
  • EG3-1RVC antibody
  • EG3RVC antibody
  • Gm11492 antibody
  • H5 antibody
  • hCDCREL-2 antibody
  • MART antibody
  • OTTMUSG00000001265 antibody
  • PNUTL2 antibody
  • RP23-168C20.1 antibody
  • SEP4 antibody
  • SEPT4 antibody

Protein level used designations for anti-Septin 4 (SEPT4) Antibodies

expression gene 3 in rat visual cortex , expression gene 3-1 in rat visual cortex , peanut-like 2 , septin-4 , septin 4 , CE5B3 beta , apoptosis-related protein in the TGF-beta signaling pathway , bradeion beta , brain protein H5 , cell division control-related protein 2 , cerebral protein 7 , peanut-like protein 2 , septin-M , M-Septin , cell division control-related protein 2b , peanut-like 2 homolog , septin H5

GENE ID SPECIES
287606 Rattus norvegicus
455160 Pan troglodytes
9100863 Paracoccidioides sp. 'lutzii' Pb01
10544005 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100012173 Monodelphis domestica
100173213 Pongo abelii
100354312 Oryctolagus cuniculus
5414 Homo sapiens
18952 Mus musculus
480571 Canis lupus familiaris
538801 Bos taurus
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