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SDPR encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. Additionally we are shipping SDPR Antibodies (31) and SDPR Kits (18) and many more products for this protein.
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identification of a novel metastasis suppressor gene, serum deprivation response (SDPR), localized to 2q32-33, a region reported to be associated with significant loss of heterozygosity in breast cancer, is reported.
Cavin-1 (show PTRF Proteins) and cavin-2 are strongly expressed within caveolae-like structures within liver sinusoidal endothelial cells of the hepatitis C-related cirrhotic liver and cavin-1 (show PTRF Proteins) would play a critical role in regulating aspects of caveolin-1 (show CAV1 Proteins).
Rather than forming a single coat complex containing the three cavin (show PTRF Proteins) family members, single-molecule analysis reveals an exquisite specificity of interactions between cavin1 (show PTRF Proteins), cavin2 and cavin3 (show PRKCDBP Proteins).
Three genes (LY96 (show LY96 Proteins), IL8 (show IL8 Proteins) DPR (show DACT1 Proteins)) were significantly downregulated over time. This finding was confirmed in a validation cohort of stroke patients (n=8).
The cavin (show PTRF Proteins) family protein Polymerase 1 and transcript release factor, SRBC (show CD2 Proteins) and serum deprivation response protein were down regulated in breast cancer cell lines and breast tumor tissue.
Study conclude that SDPR is a membrane-curvature-inducing component of caveolae, and that STB-induced membrane tubulation is facilitated by caveolae.
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
serum deprivation response
, serum deprivation response (phosphatidylserine binding protein)
, serum deprivation response protein
, serum deprivation-response protein-like
, phosphatidylserine binding protein
, phosphatidylserine-binding protein
, serum deprivation-response protein