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anti-Sestrin 3 (SESN3) Antibodies

SESN3 encodes a member of the sestrin family of stress-induced proteins. Additionally we are shipping Sestrin 3 Kits (11) and Sestrin 3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SESN3 143686 P58005
SESN3 315427  
SESN3 75747 Q9CYP7
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Top anti-Sestrin 3 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Sestrin-3 Antibody (Center Y335) (ABIN656403) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human pancreas tissue stained with antibody (Center Y335) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of Sestrin-3 Antibody (Center Y335) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis using Sestrin-3 Antibody (Center Y335) Cat.-No AP53867PU-N in A549 cell line lysates (35ug/lane). This demonstrates the Sestrin-3 antibody detected the Sestrin-3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image SESN3 antibody detects SESN3 protein by Western blot analysis. A. 30 µg Rat2 whole cell lysate/extract 7.5 % SDS-PAGE SESN3 antibody , dilution: 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A549, using SESN3, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Mouse Un-conjugated ELISA, WB SESN3 monoclonal antibody (M02), clone 2C9. Western Blot analysis of SESN3 expression in human pancreas. Western Blot detection against Immunogen (37.73 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details

SESN3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sestrin 3 Antibodies

  1. Human Polyclonal SESN3 Primary Antibody for EIA, IHC (p) - ABIN954753 : Chen, Jeon, Bhaskar, Nogueira, Sundararajan, Tonic, Park, Hay: FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor. in Developmental cell 2010 (PubMed)
    Show all 2 references for ABIN954753

  2. Human Polyclonal SESN3 Primary Antibody for IHC (p), WB - ABIN656403 : Kimball, Ravi, Gordon, Dennis, Jefferson: Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet. in The Journal of nutrition 2015 (PubMed)
    Show all 2 references for ABIN656403

  3. Human Polyclonal SESN3 Primary Antibody for EIA, WB - ABIN492727 : Meiller, Alvarez, Drané, Lallemand, Blanchard, Tovey, May: p53-dependent stimulation of redox-related genes in the lymphoid organs of gamma-irradiated--mice identification of Haeme-oxygenase 1 as a direct p53 target gene. in Nucleic acids research 2007 (PubMed)

More Antibodies against Sestrin 3 Interaction Partners

Human Sestrin 3 (SESN3) interaction partners

  1. SESN3 positively regulates the gene network module in macrophages, microglia and neurons.

  2. Suggest that inhibitory effect of ethanol on Sesn3 may play an important role in the development of ethanol-induced fatty liver.

  3. findings suggest the existence of a novel mechanism for the generation of antileukemic responses in CML (show BCR Antibodies) cells, involving upregulation of SESN3 expression.

  4. Sestrin 3 is upregulated in T2D and could influence skeletal muscle differentiation without altering glucose and lipid metabolism.

  5. HSF1 (show HSF1 Antibodies)/SESN3/reactive oxygen species/p21(Cip1/WAF1 (show CDKN1A Antibodies))-mediated deceleration of cell growth may contribute to cell defense systems protecting the organism from excessive proliferation of cells that overexpress activated Ras oncoproteins.

  6. FoxOs inhibit mTORC1 and activate Akt (show AKT1 Antibodies) by inducing the expression of Sestrin3 and Rictor (show RICTOR Antibodies)

Mouse (Murine) Sestrin 3 (SESN3) interaction partners

  1. Sesn3 liver-specific knockout mice exhibit insulin (show INS Antibodies) resistance and glucose intolerance. Sesn3 interacts with and activates mTORC2 (show CRTC2 Antibodies) and subsequently stimulates Akt (show AKT1 Antibodies) phosphorylation at Ser473.

  2. Study found that Sestrins (1,2 and 3) can inhibit mTORC1 signaling in the absence of AMPK (show PRKAA1 Antibodies) or TSC2 (show TSC2 Antibodies). Surprisingly, when coexpressed with a GTP (show AK3 Antibodies)-bound constitutively active form of RagB (show RRAGB Antibodies) (RagBQ99L), Sestrins potentiate mTORC1 signaling in the absence of amino acids.

  3. Suggest that inhibitory effect of ethanol on Sesn3 may play an important role in the development of ethanol-induced fatty liver.

  4. Concomitant ablation of Sesn2 (show SESN2 Antibodies) and Sesn3 provokes hepatic mTORC1-S6K (show RPS6KB1 Antibodies) activation and insulin (show INS Antibodies) resistance even in the absence of nutritional overload and obesity.

  5. FoxOs inhibit mTORC1 and activate Akt (show AKT1 Antibodies) by inducing the expression of Sestrin3 and Rictor (show RICTOR Antibodies)

Sestrin 3 (SESN3) Antigen Profile

Protein Summary

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Sestrin 3 (SESN3) Antibodies

  • sestrin 3 (SESN3) antibody
  • sestrin 3 (sesn3) antibody
  • sestrin 3 (LOC100354919) antibody
  • sestrin 3 (Sesn3) antibody
  • 5630400E15Rik antibody
  • BC003348 antibody
  • cb261 antibody
  • sb:cb261 antibody
  • SEST3 antibody
  • sestrin-3 antibody
  • wu:fb77c04 antibody
  • wu:fc41d03 antibody
  • wu:fd59d12 antibody
  • zgc:56722 antibody

Protein level used designations for anti-Sestrin 3 (SESN3) Antibodies

sestrin-3 , sestrin 3 , sestrin-3-like

GENE ID SPECIES
428089 Gallus gallus
485118 Canis lupus familiaris
515914 Bos taurus
100526065 Sus scrofa
406840 Danio rerio
443904 Xenopus laevis
451495 Pan troglodytes
699329 Macaca mulatta
100038137 Xenopus (Silurana) tropicalis
100354919 Oryctolagus cuniculus
100406991 Callithrix jacchus
100475423 Ailuropoda melanoleuca
100557159 Anolis carolinensis
100599268 Nomascus leucogenys
143686 Homo sapiens
315427 Rattus norvegicus
75747 Mus musculus
Selected quality suppliers for anti-Sestrin 3 (SESN3) Antibodies
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