SESN3 antibody (AA 1-310)

Catalog No. ABIN6147627

Product Details anti-SESN3 Antibody

Target: SESN3 (Sestrin 3 (SESN3))

Binding Specificity: AA 1-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SESN3

Target: SESN3 (Sestrin 3 (SESN3))

Alternative Name: SESN3 (SESN3 Products)

Synonyms: cb261 antibody, sb:cb261 antibody, zgc:56722 antibody, wu:fb77c04 antibody, wu:fc41d03 antibody, wu:fd59d12 antibody, sestrin-3 antibody, sest3 antibody, SEST3 antibody, 5630400E15Rik antibody, BC003348 antibody, sestrin 3 antibody, sestrin 3 L homeolog antibody, SESN3 antibody, sesn3 antibody, sesn3.L antibody, Sesn3 antibody

Background: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.,SESN3,SEST3,sestrin-3,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Hypoxia,Hypoxia-Regulated,SESN3

Molecular Weight: 36 kDa/41 kDa/57 kDa

Gene ID: 143686

UniProt: P58005