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anti-Sex Comb On Midleg-Like 2 (Drosophila) (SCML2) Antibodies

SCML2 encodes a member of the Polycomb group proteins. Additionally we are shipping SCML2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCML2 10389 Q9UQR0
SCML2    
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Top anti-SCML2 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB SCML2 Antibody (Center)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SCML2 antibody detected the SCML2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of SCML2 expression in HeLa (A), NCIH460 (B), Jurkat (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated DB, WB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Mouse Un-conjugated DB, WB   50 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to SCML2 on HeLa cell. [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged SCML2 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details

SCML2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


More Antibodies against SCML2 Interaction Partners

Human Sex Comb On Midleg-Like 2 (Drosophila) (SCML2) interaction partners

  1. SCML2A, an SCML2 isoform tightly associated to chromatin, contributes to PRC1 (show PRC1 Antibodies) localization and also directly enforces repression of certain Polycomb (show CBX2 Antibodies) target genes.

  2. SCML2 directly interacts with USP7 (show USP7 Antibodies) and drives its localization. SCML2 connects USP7 (show USP7 Antibodies) to PRC1.4, allowing for the stabilization of BMI1 (show BMI1 Antibodies), and USP7 (show USP7 Antibodies) is found on SCML2 and BMI1 (show BMI1 Antibodies) target genes.

  3. Because PRC1 (show PRC1 Antibodies) complexes localize to the promoters of a specific subset of developmental genes in vivo, the SLED domain of Scml2 may provide an important link connecting the PRC1 (show PRC1 Antibodies) complexes to their target genes.

  4. 1.78-A crystal structure of the two MBT (show PRTN3 Antibodies) repeats of SCML2 show significant structural similarities to the Tudor, PWWP, and chromo domains, suggesting probable evolutionary relationships and functional similarities between the MBT (show PRTN3 Antibodies) repeats and these domains.

  5. The malignant brain tumor repeats of SCML2 preferentially bind histone peptides monomethylated at lysine residues. The crystal structure of the complex reveals that the modified amino acid binds to an aromatic rich pocket.

SCML2 Antigen Profile

Protein Summary

This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development.

Gene names and symbols associated with SCML2

  • sex comb on midleg-like 2 (Drosophila) (SCML2) antibody

Protein level used designations for SCML2

sex comb on midleg-like protein 2

GENE ID SPECIES
10389 Homo sapiens
Selected quality suppliers for anti-SCML2 (SCML2) Antibodies
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