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Short Stature Homeobox 2 Proteins (SHOX2)

SHOX2 is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Additionally we are shipping Short Stature Homeobox 2 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SHOX2 6474 O60902
SHOX2 20429 P70390
SHOX2 25546 O35750
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Top Short Stature Homeobox 2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,601.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SHOX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Short Stature Homeobox 2 (SHOX2) Interaction Partners

Human Short Stature Homeobox 2 (SHOX2) interaction partners

  1. SHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing ability.

  2. SHOX2 DNA methylation (show HELLS Proteins) identified 66% of the patients with cancer subsequent to a cytological equivocal diagnosis. SHOX2 complements the cytological diagnosis and the methylation marker panel.

  3. miR (show MLXIP Proteins)-375/SHOX2 functional relationship regulates breast tumorigenesis by controlling the process of EMT (show ITK Proteins).

  4. SHOX2, like SHOX (show SHOX Proteins), regulates NPPB (show BNP Proteins) directly whilst activates ACAN (show ACAN Proteins) via its cooperation with the SOX (show PIPOX Proteins) trio (show TRIO Proteins).

  5. prognostic value of SHOX2 and SEPT9 (show SEPT9 Proteins) DNA methylation (show HELLS Proteins) in benign, paramalignant and malignant pleural effusions

  6. Elevated SHOX2 expression is associated with tumor recurrence of hepatocellular carcinoma.

  7. The combination of EBUS-TBNA and SHOX2 methylation level strongly improves the assessment of the nodal status by identifying additional malignant lesions and confirming benign nodes and therefore avoiding invasive follow-up procedures.

  8. The assay is based on quantification of methylated Short Stature Homeobox gene two (SHOX2) DNA in the specimen measured via multiplex real-time Polymerase Chain Reaction (PCR) on bisulfite-converted DNA.

  9. Shox2 regulates progression through chondrogenesis at two distinct stages--the onset of early differentiation and the transition to maturation and hypertrophy.

  10. DNA methylation (show HELLS Proteins) of PITX2 (show PITX2 Proteins) and SHOX2 is an independent prognostic biomarker for disease progression in non-small-cell lung cancer patients.

Mouse (Murine) Short Stature Homeobox 2 (SHOX2) interaction partners

  1. Results demonstrate that elimination of Shox2 in the brain results in disruptions in the development of the facial (VII (show TH Proteins)) nerves and the facial motor nucleus

  2. the Shox2-Nkx2-5 (show NKX2-5 Proteins) antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node

  3. Shox2 expression restricted to the proximal limb along with Hoxd9 (show HOXD9 Proteins) and Hoxa11 (show HOXA11 Proteins) expression, juxtaposing the distal expression of Hoxa13 (show HOXA13 Proteins) and Hoxd13 (show HOXD13 Proteins).

  4. study suggested that a certain concentration of FA causes the bone marrow toxicity by regulating the expression of Prx3 (show PRDX3 Proteins)

  5. Data indicate the importance of short stature homeobox 2 (Shox2) in the cerebellum.

  6. Shox2 regulates dorsal mesenchymal protrusion fate and development by controlling BMP signaling through the Smad (show SMAD1 Proteins)-dependent pathway to drive tissue growth and to induce Hcn4 (show HCN3 Proteins) expression

  7. phosphorylation essential for repression of Nkx2.5 (show NKX2-5 Proteins) expression during sinoatrial node development and differentiation

  8. These data extend our understanding of the role and regulation of Tbx4 (show TBX4 Proteins) and Shox2 in limb development and limb associated diseases.

  9. Although human SHOX (show SHOX Proteins) can exert similar functions to mouse Shox2 in regulating early temporomandibular joint development, it apparently has a distinct function in the regulation of those molecules that are involved in tissue homeostasis.

  10. Shox2 regulates progression through chondrogenesis at two distinct stages--the onset of early differentiation and the transition to maturation and hypertrophy.

Zebrafish Short Stature Homeobox 2 (SHOX2) interaction partners

  1. Shox2 deficiency interferes with pacemaking function in zebrafish embryos. Shox2 has a critical function in the recruitment of sinus venosus myocardium comprising the sinoatrial nodal region.

Short Stature Homeobox 2 (SHOX2) Protein Profile

Protein Summary

This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SHOX2

  • short stature homeobox 2 (SHOX2)
  • short stature homeobox 2 (shox2)
  • short stature homeobox 2 (Shox2)
  • 6330543G17Rik protein
  • OG12 protein
  • Og12x protein
  • ogi2x protein
  • Prx3 protein
  • SHOT protein
  • SHOX2 protein
  • zgc:65884 protein
  • zgc:77344 protein

Protein level used designations for SHOX2

short stature homeobox 2 , SHOX homologous gene on chromosome 3 , homeobox protein Og12X , paired-related homeobox protein SHOT , short stature homeobox protein 2 , OG-12 , paired family homeodomain protein Prx3

GENE ID SPECIES
460809 Pan troglodytes
704327 Macaca mulatta
771650 Gallus gallus
100101703 Xenopus (Silurana) tropicalis
6474 Homo sapiens
20429 Mus musculus
25546 Rattus norvegicus
394171 Danio rerio
485732 Canis lupus familiaris
525900 Bos taurus
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