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Sialic Acid Binding Ig-Like Lectin 14 Proteins (SIGLEC14)

Putative adhesion molecule. Additionally we are shipping SIGLEC14 Antibodies (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SIGLEC14 100049587 Q08ET2
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Top SIGLEC14 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$841.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SIGLEC14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Sialic Acid Binding Ig-Like Lectin 14 (SIGLEC14) Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 14 (SIGLEC14) interaction partners

  1. An unbiased screen revealed Hsp70 (show HSP70 Proteins) as a ligand for Siglec-5 (show SIGLEC5 Proteins) and Siglec-14. Hsp70 (show HSP70 Proteins) stimulation through Siglec-5 (show SIGLEC5 Proteins) delivers an anti-inflammatory signal, while stimulation through Siglec-14 is pro-inflammatory.

  2. Genome-wide association analyses revealed common DNA variants in PLG (show PLG Proteins), LPA (show APOA Proteins), and near SIGLEC14 that contribute to plasma plasminogen (show PLG Proteins) level variation.

  3. Data indicate that the Siglec-5 (show SIGLEC5 Proteins)/14 genotype influences neutrophil responses to group B Streptococcus.

  4. Siglec-14 and its downstream signaling pathway facilitate the "infection-inflammation-exacerbation" axis of COPD (show ARCN1 Proteins) disease progression

  5. Siglec-14 and Siglec-5 (show SIGLEC5 Proteins) appear to be the first glycan binding paired receptors. Near-complete sequence identity of the amino-terminal part of human Siglec-14 and Siglec-5 (show SIGLEC5 Proteins) indicates partial gene conversion between SIGLEC14 and SIGLEC5 (show SIGLEC5 Proteins).

  6. The presence of the "SIGLEC14 null" allele in all human populations we tested implies an ancient origin, while its allelic frequency is higher in Asians compared with Africans and Europeans. Siglec-14 may play some role in bacterial infection.

SIGLEC14 Protein Profile

Protein Summary

Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.

Gene names and symbols associated with SIGLEC14

  • sialic acid binding Ig-like lectin 14 (SIGLEC14)

Protein level used designations for SIGLEC14

sialic acid-binding Ig-like lectin 14 , siglec-14

GENE ID SPECIES
100049587 Homo sapiens
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