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anti-Sialophorin (SPN) Antibodies

The protein encoded by SPN is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. Additionally we are shipping CD43 Proteins (14) and CD43 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPN 6693 P16150
SPN 24796  
SPN 20737 P15702
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Top anti-CD43 Antibodies at antibodies-online.com

Showing 10 out of 470 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SPN Antibody (Center) in HL-60 cell line lysates (35µg/lane). SPN (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD43:RPE (ABIN119532). 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated FACS 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse FITC FACS Staining of human peripheral blood lymphocytes with Mouse anti Human CD43: FITC (ABIN119529). 0.1 mg Log in to see 6 to 8 Days
$489.50
Details
Rat Mouse Un-conjugated FACS, IHC (fro), IHC (p)   0.1 mg Log in to see 6 to 8 Days
$198.00
Details
Human Mouse FITC FACS 50 Tests Log in to see 6 to 8 Days
$401.50
Details
Rat Mouse FITC FACS ABIN120444 staining of rat splenocytes. 0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated Func, FACS, IHC (p), IP, WB   0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Mouse Un-conjugated FACS, IHC (p) 0.1 mg Log in to see 10 to 12 Days
$392.70
Details
Human Mouse FITC FACS, IF 100 Tests Log in to see 6 to 8 Days
$456.50
Details

SPN Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CD43 Antibodies

  1. Human Monoclonal CD43 Primary Antibody for FACS - ABIN1106373 : Caplan, Dennis: Genetically linked scientists. The one-two punch for NFATp knockout. in The Journal of experimental medicine 2000 (PubMed)
    Show all 8 references for ABIN1106373

  2. Human Monoclonal CD43 Primary Antibody for FACS - ABIN1106370 : Hernandez, Nguyen, He, Wang, Ardman, Green, Fukuda, Baum: Galectin-1 binds different CD43 glycoforms to cluster CD43 and regulate T cell death. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 7 references for ABIN1106370

  3. Rat (Rattus) Monoclonal CD43 Primary Antibody for FACS, IHC (fro) - ABIN120446 : Barclay: The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. in Immunology 1981 (PubMed)
    Show all 6 references for ABIN120446

  4. Rat (Rattus) Monoclonal CD43 Primary Antibody for FACS - ABIN120444 : Brown, Williams: Lymphocyte cell surface glycoproteins which bind to soybean and peanut lectins. in Immunology 1982 (PubMed)
    Show all 5 references for ABIN120444

  5. Human Polyclonal CD43 Primary Antibody for EIA, WB - ABIN951313 : Urano-Tashiro, Yajima, Takashima, Takahashi, Konishi: Binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50. in Infection and immunity 2008 (PubMed)
    Show all 2 references for ABIN951313

  6. Human Monoclonal CD43 Primary Antibody for FACS, IF - ABIN1106375 : Poppema, Hollema, Visser, Vos: Monoclonal antibodies (MT1, MT2, MB1, MB2, MB3) reactive with leukocyte subsets in paraffin-embedded tissue sections. in The American journal of pathology 1987 (PubMed)

  7. Human Monoclonal CD43 Primary Antibody for Func, FACS - ABIN120595 : Kosina, Plisek, Dostal, Moravkova, Cermak, Preis, Lukes, Kracmarova, Krausova: [Invasive streptococcal infections] in Klinická mikrobiologie a infekc?ní lékar?ství 2008 (PubMed)

  8. Human Monoclonal CD43 Primary Antibody for FACS - ABIN119529 : Anzai, Gotoh, Shibayama, Broxmeyer: Modulation of integrin function in hematopoietic progenitor cells by CD43 engagement: possible involvement of protein tyrosine kinase and phospholipase C-gamma. in Blood 1999 (PubMed)

More Antibodies against CD43 Interaction Partners

Human Sialophorin (SPN) interaction partners

  1. Forty percent of adenoid cystic carcinomas showed staining for CD43, while no cases of basal cell carcinoma were positive

  2. CD43 expression is a novel adverse prognostic factor for patients with diffuse large B-cell lymphomas

  3. CD43 polymorphisms are associated with TB susceptibility.

  4. Host membrane protein PSGL-1 (show SELPLG Antibodies), CD43, and CD44 (show CD44 Antibodies) association with assembling HIV-1 Gag is driven by polybasic sequences present in the cytoplasmic tails of the membrane proteins and in Gag.

  5. When used as vaccine in mice, the 2/165 phagotope raised antibodies against the UN1/CD43 antigen, indicating that the 2/165 phagotope mimicked the UN1 antigen structure, and could represent a novel immunogen for cancer immunotherapy

  6. CD43 promotes cells transformation by preventing merlin (show NF2 Antibodies)-mediated contact inhibition of growth.

  7. We conclude that CD43 is an adverse prognostic marker in DLBCL, and is preferentially expressed in the non-GCB (show GBA Antibodies) subgroup.

  8. CD43 regulates the threshold for T cell activation by targeting Cbl (show CBL Antibodies) functions.

  9. Taken together, these results show that elevated calcium levels induce CD43 capping, and macrophages remove the cells if their nucleolin (show NCL Antibodies) receptors can bind to the poly-N-acetyllactosaminyl chains of capped CD43.

  10. Targeting CD43 in A549 lung cancer cells, increased homotypic adhesion, decreased heterotypic adhesion and transendothelial migration, increased susceptibility to apoptosis and increased vulnerability to lysis by NK cells

Mouse (Murine) Sialophorin (SPN) interaction partners

  1. glycosylation status of CD43 protein on leukemia cells is associated with sensitivity to CTL-mediated cytolysis

  2. findings demonstrate that CD43 is a major E-selectin (show SELE Antibodies) ligand in Th17 cells that functions independent of P-selectin glycoprotein ligand-1 (show SELPLG Antibodies)

  3. CD43 may be an important mediator of macrophage lipid homeostasis, thereby affecting macrophage foam cell formation and ultimately atherosclerotic plaque development.

  4. We have identified a robust physiologic role for CD43 in a relevant animal model and established an important in vivo function for CD43-dependent regulation of IFN-gamma (show IFNG Antibodies) production.

  5. Results show that while CD43 binding to ezrin-radixin-moesin (show MSN Antibodies) proteins is crucial for S76 phosphorylation, CD43 movement and regulation of T-cell migration can occur through an ERM (show ETV5 Antibodies)-independent, phosphorylation-dependent mechanism.

  6. study found that the M. tuberculosis Cpn60.2 molecular chaperone (show HSP90AA1 Antibodies) is the major mycobacterial surface ligand that interacts with CD43 to stabilize the interaction between M. tuberculosis and the macrophage

  7. Transient resistance to B16F10 melanoma growth and metastasis in CD43-/- mice.

  8. CD43 engagement and signaling are involved in the costimulatory and antiapoptotic effects of enzymatically inactive mutant trypanosomal trans-sialidase when it binds highly sialylated mucin (show SLC13A2 Antibodies) CD43 on the T cell surface.

  9. Cd43 displays dynamic roles in T cell immunity: a positive regulatory role in costimulation and trafficking of T cells to the central nervous system, and a negative regulatory role in the down-modulation of an immune response.

  10. Delayed onset of experimental autoimmune encephalomyelitis in CD43-deficient immunized mice and in recipients of adoptively transferred CD43-/- cells is characterized by significant reduction of T cell trafficking to the brain and spinal cord.

CD43 (SPN) Antigen Profile

Protein Summary

The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response.

Gene names and symbols associated with anti-Sialophorin (SPN) Antibodies

  • sialophorin (SPN) antibody
  • sialophorin (Spn) antibody
  • A630014B01Rik antibody
  • Cd43 antibody
  • Galgp antibody
  • gpL115 antibody
  • Lsn antibody
  • Lsn1 antibody
  • Ly-48 antibody
  • Ly48 antibody

Protein level used designations for anti-Sialophorin (SPN) Antibodies

galactoglycoprotein , leukocyte sialoglycoprotein , leukosialin , sialophorin (gpL115, leukosialin, CD43) , W3/13 antigen , leukosianin , 3E8 antigen , B-cell differentiation antigen LP-3 , lymphocyte antigen 48

GENE ID SPECIES
6693 Homo sapiens
24796 Rattus norvegicus
20737 Mus musculus
Selected quality suppliers for anti-CD43 (SPN) Antibodies
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