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anti-Sirtuin 7 (SIRT7) Antibodies

SIRT7 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 7 Proteins (16) and Sirtuin 7 Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIRT7 51547 Q9NRC8
SIRT7 209011 Q8BKJ9
SIRT7 303745  
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Top anti-Sirtuin 7 Antibodies at antibodies-online.com

Showing 10 out of 171 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIRT7 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIRT7 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: SH-SYSY cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of SIRT7 (arrow) using SIRT7 Antibody (C-term) (ABIN390182). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SIRT7 gene (Lane 2). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Chicken Un-conjugated EIA, WB Western blot analysis of SIRT7 in 293 cell lysate with SIRT7 antibody at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ICC, IF, IP SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 Immunocytochemistry/Immunofluorescence: SIRT7 Antibody [ABIN2597682] - SIRT7 antibody was tested in U2OS cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (fro), IF (p), IHC (p), WB Mouse splenocytes probed with Rabbit Anti-SIRT7 Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated WB Western Blot: SIRT7 Antibody [ABIN43538884] - Analysis of SIRT7 in A) human liver and B) PBMC lysate using this antibody at 1 ug/ml. 0.1 mg Log in to see 5 to 7 Days
$317.63
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- SIRT7 Picoband antibody, Western blotting All lanes: Anti SIRT7  at 0.5ug/ml Lane 1: Rat Spleen Tissue Lysate at 50ug Lane 2: Rat Brain Tissue Lysate at 50ug Lane 3: Rat Intestine Tissue Lysate at 50ug Lane 4: SMMC Whole Cell Lysate at 40ug Lane 5: JURKAT Whole Cell Lysate at 40ug Predicted bind size: 45KD Observed bind size: 45KD Anti- SIRT7 Picoband antibody, IHC(P) IHC(P): Mouse Spleen Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details

SIRT7 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Sirtuin 7 Antibodies

  1. Human Polyclonal SIRT7 Primary Antibody for IHC (p), WB - ABIN390182 : Wang, Yi, Li, Cai, He, Ni, Zhou, Cheng, Jin, Fan, Qiu: Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection. in BMC cancer 2014 (PubMed)
    Show all 3 references for ABIN390182

  2. Human Polyclonal SIRT7 Primary Antibody for IHC (fro), IF (p) - ABIN760571 : Takumida, Takumida, Anniko: Localization of sirtuins in the mouse inner ear. in Acta oto-laryngologica 2014 (PubMed)
    Show all 2 references for ABIN760571

  3. Human Polyclonal SIRT7 Primary Antibody for EIA, WB - ABIN783618 : Salminen, Kaarniranta: SIRT1: regulation of longevity via autophagy. in Cellular signalling 2009 (PubMed)
    Show all 2 references for ABIN783618

  4. Human Polyclonal SIRT7 Primary Antibody for EIA, IHC (p) - ABIN358736 : Frye: Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. in Biochemical and biophysical research communications 2000 (PubMed)

  5. Human Polyclonal SIRT7 Primary Antibody for WB - ABIN4353888 : Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. in Cancer 2011 (PubMed)

  6. Human Polyclonal SIRT7 Primary Antibody for ICC, IF - ABIN259767 : Zhang, Li, Deng, Liu, Chen, Tang, Wang, Cao, Fang, Wen, Xu, Chen, Shi, Li, Xie, Tang: Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. in Nucleic acids research 2016 (PubMed)

  7. Cow (Bovine) Polyclonal SIRT7 Primary Antibody for WB - ABIN2779622 : Ashraf, Zino, Macintyre, Kingsmore, Payne, George, Shiels: Altered sirtuin expression is associated with node-positive breast cancer. in British journal of cancer 2006 (PubMed)

More Antibodies against Sirtuin 7 Interaction Partners

Human Sirtuin 7 (SIRT7) interaction partners

  1. our study suggests that SIRT7 functions as an oncogene (show RAB1A Antibodies) in non-small cell lung cancer (NSCLC), and miR (show MLXIP Antibodies)-3666 can target SIRT7 to inhibit NSCLC cell growth by promoting the pro-apoptotic signaling pathway

  2. SIRT7 trans-represses RPS7 (show RPS7 Antibodies) gene in the presence of HBx protein.HBx enhances intracellular stability of SIRT7 protein.

  3. Data indicate that compared to non-neoplastic endometria (NNE (show ENO1 Antibodies)), endometrial cancer (EC) showed SIRT7 mRNA overexpression, whereas SIRT1 (show SIRT1 Antibodies), SIRT2 (show SIRT2 Antibodies), SIRT4 (show SIRT4 Antibodies) and SIRT5 (show SIRT5 Antibodies) were underexpressed, and no significant differences were observed for SIRT3 (show SIRT3 Antibodies) and SIRT6 (show SIRT6 Antibodies).

  4. This study showed that SIRT7 can be activated by DNA to hydrolyze the acetyl group from lysine residues in vitro on histone peptides and histones in the chromatin context.

  5. Novel interactions of TPPII (show Tpp2 Antibodies), p53 (show TP53 Antibodies), and SIRT7 presented in this study might contribute to the knowledge of the regulatory effects of these proteins on apoptotic pathways and to the understanding mechanisms of aging and lifespan regulation.

  6. SIRT7 deacetylates U3-55k (show RRP9 Antibodies), enhancing U3-55k (show RRP9 Antibodies) binding to U3 snoRNA, which is a prerequisite for pre-rRNA processing.

  7. this is the first report on the regulation mechanism of SIRT7 gene, in which, HDAC3 (show HDAC3 Antibodies) collaborated with C/EBPalpha (show CEBPA Antibodies) to occupy its responding element in the upstream region of SIRT7 gene and repressed its expression in human cells.

  8. SIRT3 (show SIRT3 Antibodies) and SIRT7 possess tumour suppressor properties in the context of pancreatic cancer.

  9. Sirt7 expression was implicated with high histological grade and independently predicted poor clinical outcome in patients with breast cancer, suggesting that Sirt7 might play a role in the malignant progression of breast cancer.

  10. SIRT7 might play a role of oncogene (show RAB1A Antibodies) in ovarian malignancy. Down-regulation of SIRT7 significantly reduced ovarian cancer cell growth, repressed colony formation and increased cancer cell apoptosis; up-regulation promoted the migration of cancer cells.

Mouse (Murine) Sirtuin 7 (SIRT7) interaction partners

  1. miR (show MLXIP Antibodies)-93 inhibits the metabolic target Sirt7, which we identified as a major driver of in vivo adipogenesis via induction of differentiation and maturation of early adipocyte precursors.

  2. The role of SIRT7 has emerged in protein synthesis, chromatin remodelling, cellular survival and lipid metabolism.

  3. SIRT7 stabilizes and activates the GABP alpha (show GABPA Antibodies)/GABPbeta complex via deacetylation of GABPbeta1.

  4. SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.

  5. Study identifies SIRT7 as a cofactor of Myc (show MYC Antibodies) for transcriptional repression and delineates a druggable regulatory branch of the ER stress response that prevents and reverts fatty liver disease.

  6. Mybbp1a (show MYBBP1A Antibodies) is a novel negative regulator of Sirt7.

  7. SirT7 plays a dominant role in the growth inhibition of the P19 (show CDKN2D Antibodies) cells.

  8. SIRT7 is a positive regulator of Pol I transcription and is required for cell viability in mammals.

  9. Suggest a critical role of Sirt7 in the regulation of stress responses and cell death in the heart. Enhanced p53 (show TP53 Antibodies) activation by lack of Sirt7-mediated deacetylation contributes to the heart phenotype of Sirt7 mutant mice.

  10. Using Sirt7 knockout and overexpressing cells we demonstrate an anti-proliferative role of Sirt7. We also show that Sirt7 expression inversely correlates with the tumorigenic potential of several murine cell lines

Sirtuin 7 (SIRT7) Antigen Profile

Protein Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Gene names and symbols associated with anti-Sirtuin 7 (SIRT7) Antibodies

  • sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) antibody
  • novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) (CH211-258L4.6) antibody
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2) antibody
  • sirtuin 7 (SIRT7) antibody
  • sirtuin 7 (Sirt7) antibody
  • LOC796135 antibody
  • SIR2L7 antibody
  • SIRT7 antibody

Protein level used designations for anti-Sirtuin 7 (SIRT7) Antibodies

sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin 7 , novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) , NAD-dependent deacetylase sirtuin-7 , sirtuin , NAD-dependent protein deacetylase sirtuin-7 , SIR2-like protein 7 , regulatory protein SIR2 homolog 7 , silent mating type information regulation 2, S.cerevisiae, homolog 7 , sir2-related protein type 7 , sirtuin type 7 , NAD-dependent deacetylase sirtuin 7

GENE ID SPECIES
454975 Pan troglodytes
796135 Danio rerio
422093 Gallus gallus
51547 Homo sapiens
209011 Mus musculus
303745 Rattus norvegicus
483371 Canis lupus familiaris
100125965 Sus scrofa
505662 Bos taurus
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