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anti-Slingshot Homolog 1 (Drosophila) (SSH1) Antibodies

The protein encoded by SSH1 belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. Additionally we are shipping SSH1 Proteins (5) and SSH1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse SSH1 SSH1 231637 Q76I79
SSH1 54434 Q8WYL5
SSH1    
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Top anti-SSH1 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB SSH1 Antibody (N-term) (ABIN1881835) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the SSH1 antibody detected the SSH1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IP, WB Western Blot and Immunoprecipitation: SSH1 Antibody [ABIN253142] - Detection of Human SSH1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- SSH1 antibody ABIN253142 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. SSH1 was also immunoprecipitated by rabbit anti-SSH1 antibodies ABIN253143 and ABIN253144, which recognize downstream epitopes.Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Fruit Fly Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IP, WB Western Blot and Immunoprecipitation: SSH1 Antibody [ABIN253143] - Detection of Human SSH1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- SSH1 antibody ABIN253143 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. SSH1 was also immunoprecipitated by rabbit anti-SSH1 antibodies ABIN253142 and ABIN253144, which recognize other epitopes. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B). 0.1 mL Log in to see 5 to 7 Days
$486.94
Details
Human Rabbit Un-conjugated IP, WB Western Blot and Immunoprecipitation: SSH1 Antibody [ABIN253144] - Detection of Human SSH1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- SSH1 antibody ABIN253144 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. SSH1 was also immunoprecipitated by rabbit anti-SSH1 antibodies ABIN253142 and ABIN253143, which recognize upstream epitopes. Detection: Chemiluminescence with exposure times of 30 seconds (A and B). 0.1 mL Log in to see 5 to 7 Days
$486.94
Details
Human Mouse Un-conjugated ELISA, FACS, ICC   100 μL Log in to see 8 to 11 Days
$550.00
Details
Human Mouse Un-conjugated ELISA, FACS, IHC   100 μL Log in to see 8 to 11 Days
$550.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$415.58
Details
Human Mouse Un-conjugated IF, ELISA, WB SSH1 monoclonal antibody (M02), clone 1D2. Western Blot analysis of SSH1 expression in HeLa. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

SSH1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Fruit Fly (Drosophila melanogaster)


Top referenced anti-SSH1 Antibodies

  1. Human Polyclonal SSH1 Primary Antibody for WB - ABIN1881835 : Niwa, Nagata-Ohashi, Takeichi, Mizuno, Uemura: Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. in Cell 2002 (PubMed)
    Show all 6 references for ABIN1881835

  2. Fruit Fly (Drosophila melanogaster) Polyclonal SSH1 Primary Antibody for EIA, WB - ABIN492729 : Kligys, Yao, Yu, Jones: 14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 6 references for ABIN492729

  3. Human Polyclonal SSH1 Primary Antibody for IP, WB - ABIN253142 : Guo, Ma, Zhang, Sun, Niu, Ying, Zhang: Pivotal Advance: PKCzeta is required for migration of macrophages. in Journal of leukocyte biology 2009 (PubMed)
    Show all 2 references for ABIN253142

More Antibodies against SSH1 Interaction Partners

Mouse (Murine) Slingshot Homolog 1 (Drosophila) (SSH1) interaction partners

  1. Caspase-11 (show CASP4 Antibodies) targets cofilin (show CFL1 Antibodies) via the RhoA GTPase, whereas caspase-1 (show CASP1 Antibodies) engages the Slingshot phosphatase

  2. SSH1L knockdown, like S1P (show S1PR1 Antibodies) treatment, increased cardiomyocyte survival and preserved mitochondrial integrity after oxidative stress

  3. EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.

  4. PDGF (show PDGFA Antibodies) activates SSH1L in VSMC by a mechanism that involves Nox1 (show NOX1 Antibodies)-mediated oxidation of 14-3-3 (show YWHAQ Antibodies) and Ser (show SIGLEC1 Antibodies)-834 SSH1L auto-dephosphorylation.

  5. Knockdown of SSH1 expression by RNA interference significantly suppressed stress fiber formation in C2C12 myoblast cells, indicating a role for SSH1 in stress fiber formation or stabilization in cells.

Human Slingshot Homolog 1 (Drosophila) (SSH1) interaction partners

  1. Results reveal that SSH1L is upregulated in a subset of PCs and that the SSH1L/cofilin-1 (show CFL1 Antibodies) signal pathway is associated positively in PC with cell migration.

  2. Authors show that viral penetration-induced calcium release facilitated herpes simplex virus type 1 intracellular trafficking through activating slingshot 1 (SSH), a phosphatase regulating actin filament dynamics.

  3. The association of IRS4 (show IRS4 Antibodies) with SSH1 contributes to localized activation of cofilin (show CFL1 Antibodies) in membrane protrusions.

  4. Slingshot 1 downregulation in neuronal cells inactivates cofilin (show CFL1 Antibodies) to facilitate HSV-1 replication.

  5. Thus this study provides evidence for a novel role of LIMK1 (show LIMK1 Antibodies) and SSH-1L in selectively regulating endothelial cell inflammation associated with intravascular coagulation.

  6. Our work provides evidence that supports the positive role of SSH1L in the mechanism of stem cell differentiation into cardiomyocyte-like cells.

  7. A high expression of SSH-1L in peripheral eosinophils in acute exacerbations of asthma may play a role in the activation and migration of eosinophils.

  8. EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.

  9. identified Ser (show SIGLEC1 Antibodies) 402 as a new phosphorylation site within the catalytic domain of human slingshot 1 (SSH1).

  10. Results show the significance of SSH1L in estrogen-induced osteoblastogenic differentiation in favor of adipogenic differentiation from hMSCs.

SSH1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with SSH1

  • slingshot homolog 1 (Drosophila) (Ssh1) antibody
  • slingshot protein phosphatase 1 (SSH1) antibody
  • AW551225 antibody
  • Gm1394 antibody
  • Gm1395 antibody
  • mSSH-1L antibody
  • SSH-1 antibody
  • SSH1L antibody

Protein level used designations for SSH1

SSH-1L , SSH-like protein 1 , protein phosphatase Slingshot homolog 1 , slingshot 1L , slingshot-like 1 , hSSH-1L , slingshot homolog 1

GENE ID SPECIES
231637 Mus musculus
54434 Homo sapiens
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