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anti-Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8) Antibodies

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMG8 74133 Q8VE18
SMG8 55181 Q8ND04
SMG8    
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Top anti-SMG8 Antibodies at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-C17orf71 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate WB Suggested Anti-C17orf71  Antibody Titration: 0.2-1 µg/mL  Positive Control:.21_B cell lysate  SMG8 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB C17ORF71 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IF, IP, IHC (p)   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry of Human lung cancer using SMG8 Polyclonal Antibody at dilution of 1:50 200 μL Log in to see 8 to 9 Days
$588.50
Details

SMG8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human , ,


Rat (Rattus)


More Antibodies against SMG8 Interaction Partners

Human Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8) interaction partners

  1. knockdown of SMG-8 produced the best effect for restoring defective mRNA and protein levels without affecting cell growth, cell-cycle progression, or endoplasmic reticulum stress in Ullrich congenital muscular dystrophy fibroblasts

  2. large-scale conformational changes induced by SMG-8 after SMG-9 (show SMG9 Antibodies)-mediated recruitment tune SMG-1 (show SMG1 Antibodies) kinase activity to modulate nonsense-mediated mRNA decay

SMG8 Antigen Profile

Protein Summary

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity).

Gene names and symbols associated with SMG8

  • smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG8) antibody
  • smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg8) antibody
  • SMG8 nonsense mediated mRNA decay factor (SMG8) antibody
  • 1200011M11Rik antibody
  • C17orf71 antibody
  • C19H17orf71 antibody

Protein level used designations for SMG8

protein SMG8 , protein smg-8 homolog , CG6729 gene product , amplified in breast cancer gene 2 protein , smg-8 homolog, nonsense mediated mRNA decay factor

GENE ID SPECIES
522040 Bos taurus
74133 Mus musculus
55181 Homo sapiens
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