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SMG8 antibody
SMG8
Reactivity: Human, Mouse
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SMG8 Antibody
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Target
See all SMG8 Antibodies
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
Reactivity
All reactivities for SMG8 antibodies
Human, Mouse
Host
All hosts for SMG8 antibodies
Rabbit
Clonality
All clonalities for SMG8 antibodies
Polyclonal
Conjugate
All conjugates for SMG8 antibodies
This SMG8 antibody is un-conjugated
Application
All applications for SMG8 antibodies
Immunohistochemistry (IHC), ELISA
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human SMG8
Isotype
IgG
Alternatives
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anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (AA 575-624) antibody
SMG8
Reactivity: Human, Mouse, Cow, Horse, Rabbit, Pig, Rat, Dog, Guinea Pig, Bat, Monkey
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:25-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SMG8
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Target
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
Alternative Name
SMG8 (SMG8 Products )
Synonyms
C17orf71 antibody, 1200011M11Rik antibody, C19H17orf71 antibody, SMG8, nonsense mediated mRNA decay factor antibody, smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, Protein smg-8 antibody, SMG8 antibody, Smg8 antibody, smg-8 antibody
Background
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
NCBI Accession
NP_060619
UniProt
Q8ND04
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