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Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Additionally we are shipping SMG9 Proteins (2) and many more products for this protein.
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Mutations in SMG9 cause a multiple congenital anomaly syndrome in humans and mice
IQGAP1 (show IQGAP1 Antibodies) protein, an actin cytoskeleton modifier acts as a binding partner with SMG-9 and this binding is regulated by phosphorylation of SMG-9 at Tyr (show TYR Antibodies)-41.
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with smg1 and smg8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between smg1 and smg8 (By similarity).
Protein smg-9 homolog
, protein SMG9
, protein smg-9 homolog
, smg-9 homolog, nonsense mediated mRNA decay factor