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Smith-Magenis Syndrome Chromosome Region, Candidate 7 Proteins (SMCR7)

SMCR7 encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. Additionally we are shipping SMCR7 Antibodies (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMCR7 125170 Q96C03
Mouse SMCR7 SMCR7 237781 Q5NCS9
SMCR7 443935  
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Top SMCR7 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,157.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SMCR7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Xenopus laevis

More Proteins for Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) Interaction Partners

Human Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) interaction partners

  1. The results indicate that Drp1 (show CRMP1 Proteins)-dependent mitochondrial fission through MiD49/MiD51 (show SMCR7L Proteins) regulates cristae remodeling during intrinsic apoptosis.

  2. MIEF1 (show SMCR7L Proteins) and MIEF2 are differentially expressed in human tissues during development

  3. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.

  4. we find that either MiD49 or MiD51 (show SMCR7L Proteins) can mediate Drp1 (show CRMP1 Proteins) recruitment and mitochondrial fission in the absence of Fis1 (show FIS1 Proteins) and Mff (show MFF Proteins).

  5. Mitochondrial outer membrane protein that recruits fission mediator Drp1 to the mitochondrial surface.

Mouse (Murine) Smith-Magenis Syndrome Chromosome Region, Candidate 7 (SMCR7) interaction partners

  1. This paper combines confocal live-cell imaging with correlative cryogenic fluorescence microscopy and soft x-ray tomography to link MiD49 and MiD51 (show SMCR7L Proteins) to the involvement of the endoplasmic reticulum in mitochondrial fission.

  2. Determined the crystal structure and fperformed unctional analysis of mouse MiD49.

  3. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.

SMCR7 Protein Profile

Protein Summary

This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SMCR7

  • Smith-Magenis syndrome chromosome region, candidate 7 (SMCR7)
  • Smith-Magenis syndrome chromosome region, candidate 7 (smcr7)
  • Smith-Magenis syndrome chromosome region, candidate 7 homolog (human) (Smcr7)
  • AI482195 protein
  • Gm11 protein
  • mid49 protein

Protein level used designations for SMCR7

Smith-Magenis syndrome chromosomal region candidate gene 7 protein , mitochondrial dynamic protein MID49 , mitochondrial dynamic protein of 49 kDa , Smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog , mitochondrial dynamic protein of 49 kDa homolog , smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog

GENE ID SPECIES
125170 Homo sapiens
443935 Xenopus laevis
237781 Mus musculus
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