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SMCR7 encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. Additionally we are shipping SMCR7 Antibodies (6) and many more products for this protein.
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These findings and data showing MARCH5 (show MARCH5 Proteins)-dependent degradation of MiD49 upon stress support the possibility that MARCH5 (show MARCH5 Proteins) regulation of MiD49 is a novel mechanism controlling mitochondrial fission and, consequently, the cellular response to stress.
The results indicate that Drp1 (show CRMP1 Proteins)-dependent mitochondrial fission through MiD49/MiD51 (show SMCR7L Proteins) regulates cristae remodeling during intrinsic apoptosis.
MIEF1 (show SMCR7L Proteins) and MIEF2 are differentially expressed in human tissues during development
MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria.
we find that either MiD49 or MiD51 (show SMCR7L Proteins) can mediate Drp1 (show CRMP1 Proteins) recruitment and mitochondrial fission in the absence of Fis1 (show FIS1 Proteins) and Mff (show MFF Proteins).
Mitochondrial outer membrane protein that recruits fission mediator Drp1 to the mitochondrial surface.
This paper combines confocal live-cell imaging with correlative cryogenic fluorescence microscopy and soft x-ray tomography to link MiD49 and MiD51 (show SMCR7L Proteins) to the involvement of the endoplasmic reticulum in mitochondrial fission.
Determined the crystal structure and fperformed unctional analysis of mouse MiD49.
This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Smith-Magenis syndrome chromosomal region candidate gene 7 protein
, mitochondrial dynamic protein MID49
, mitochondrial dynamic protein of 49 kDa
, Smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog
, mitochondrial dynamic protein of 49 kDa homolog
, smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog