anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Antibodies

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. Additionally we are shipping Sodium Channel, Voltage-Gated, Type III, beta Subunit Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCN3B 235281 Q8BHK2
SCN3B 245956 Q9JK00
SCN3B 55800 Q9NY72
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Top anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: SCN3B Sample Tissue: Human DLD1 Antibody Dilution: 1.0ug/ml WB Suggested Anti-SCN3B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, B:Hep G2, 12% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Cow Rabbit Un-conjugated IHC (p), WB Brain, cortex 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti SCN3B Polyclonal Antibody, Unconjugated (ABIN872574) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using SCN3B antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Mouse HRP ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg Log in to see 2 to 3 Days
$422.40
Details
Human Mouse FITC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg Log in to see 2 to 3 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg Log in to see 2 to 3 Days
$429.00
Details
Human Mouse Biotin ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 3 Monoclonal Antibody, Clone S396-29 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 3 Antibody (D) Composite. Western Blot analysis of Mouse Brain showing detection of ~40 kDa Nav Beta 3 protein using Mouse Anti-Nav Beta 3 Monoclonal Antibody, Clone S396-29 . Lane 1: MW Ladder. Lane 2: Mouse Brain. Load: 20 µg. Primary Antibody: Mouse Anti-Nav Beta 3 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Predicted/Observed Size: ~40 kDa. 100 μg Log in to see 2 to 3 Days
$431.20
Details

SCN3B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit Antibodies

  1. Cow (Bovine) Polyclonal SCN3B Primary Antibody for WB - ABIN2780215 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 4 references for 2780215

More Antibodies against Sodium Channel, Voltage-Gated, Type III, beta Subunit Interaction Partners

Mouse (Murine) Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) interaction partners

  1. This study demonistrated that scn3b gene expression in mouse dorsal raphe nucleus

  2. deficiency in Scn3b results in significant atrial electrophysiological and intracardiac conduction abnormalities

  3. SCN3B mediates a p53 (show TP53 Antibodies)-dependent apoptotic pathway and may be a candidate for gene therapy combined with anticancer drugs.

  4. Bipolar electrogram and monophasic action potential recordings from the ventricles of Langendorff-perfused Scn3b(-/-) hearts demonstrated ventricular tachycardias induced by programmed electrical stimulation.

Human Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) interaction partners

  1. Contribution of Cardiac Sodium Channel (show SCN5A Antibodies) beta-Subunit (show POLG Antibodies) Variants to Brugada Syndrome.

  2. In a nonreferred nationwide Danish cohort of SIDS (show IDS Antibodies) cases, up to 5/66 (7.5%) of SIDS (show IDS Antibodies) cases can be explained by genetic variants in the sodium channel complex genes.

  3. SCN1 (show ELANE Antibodies)-3B the gene that encode respectively a- and b-subunits of the cardiac fast voltage-gated sodium channel, have been linked to atrial fibrillation.

  4. The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A (show SCN5A Antibodies)-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5 (show SCN5A Antibodies).

  5. three mutations in SCN3B were investigated electrophysiologically and all led to loss of function in the sodium current, supporting the hypothesis that decreased sodium current enhances atrial fibrillation susceptibility

  6. The researchers found evidence of an association between SCN3B subunit mutations and sudden infant death syndrome pathogenesis.

  7. The sodium channel {beta}3-subunit induces multiphasic gating in NaV1.3 (show SCN3A Antibodies) and affects fast inactivation via distinct intracellular regions.

  8. This study identifies the first atrial fibrillation(AF) -associated mutation in SCN3B, and suggests that mutations in SCN3B may be a new pathogenic cause of AF.

  9. Study provides molecular and cellular evidence implicating mutations in SCN3B as a cause of idiopathic ventricular fibrillation.

  10. SCN3B mediates a p53 (show TP53 Antibodies)-dependent apoptotic pathway and may be a candidate for gene therapy combined with anticancer drugs.

Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Antigen Profile

Protein Summary

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with SCN3B

  • sodium channel, voltage-gated, type III, beta (SCN3B) antibody
  • sodium channel, voltage-gated, type III, beta (Scn3b) antibody
  • sodium channel, voltage-gated, type III, beta subunit (SCN3B) antibody
  • sodium channel, voltage-gated, type III, beta subunit (Scn3b) antibody
  • 1110001K16Rik antibody
  • 4833414B02Rik antibody
  • HSA243396 antibody
  • SCNB3 antibody

Protein level used designations for SCN3B

sodium channel subunit beta-3 , brain and heart sodium channel beta 3 subunit , sodium channel beta 3 subunit , voltage-gated sodium channel beta-3 subunit

GENE ID SPECIES
540925 Bos taurus
235281 Mus musculus
245956 Rattus norvegicus
55800 Homo sapiens
610239 Canis lupus familiaris
100713021 Cavia porcellus
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