anti-Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 1 (SLC10A1) Antibodies

The protein encoded by SLC10A1 belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Additionally we are shipping SLC10A1 Kits (6) and SLC10A1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC10A1 20493 O08705
SLC10A1 6554 Q14973
SLC10A1 24777 P26435
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Top anti-SLC10A1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-SLC10A1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- SLC10A1 Picoband antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Observed bind size: 45, 50KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SLC10A1 antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti-SLC10A1 antibody, Western blotting All lanes: Anti SLC10A1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 1: Rat Brain Tissue Lysate at 50ug Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, WB SLC10A1 Antibody (C-term) (ABIN651897) western blot analysis in K562 cell line lysates (15 µg/lane). This demonstrates the SLC10A1 antibody detected the SLC10A1 protein (arrow). SLC10A1 Antibody (C-term) (ABIN651897) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Mouse kidney cells probed with Rabbit Anti-NTCP/SLC10A1 Polyclonal Antibody, FITC Conjugated (ABIN675908-FITC) (green) at 1:50 for 40 minutes compared to control cells (red). Mouse liver cells probed with Rabbit Anti-NTCP/SLC10A1 Polyclonal Antibody, FITC Conjugated (ABIN675908-FITC) (green) at 1:50 for 40 minutes compared to control cells (red). 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Liver, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Cy3 FACS, IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy7 FACS, IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5.5 FACS, IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

SLC10A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against SLC10A1 Interaction Partners

Mouse (Murine) Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 1 (SLC10A1) interaction partners

  1. NTCP and OATP (show SLCO1A2 Antibodies) isoforms cooperatively form a stable bile acid uptake machinery in mice, whereas NTCP is predominant in humans.

  2. Isoniazid/rifampicin administration significantly down-regulated the expression of hepatic bile acids transporters Ntcp and Bsep (show ABCB11 Antibodies) in liver.

  3. Ntcp plasma membrane localization is regulated by hyperosmolarity and tauroursodeoxycholate

  4. hepatic transporters Ntcp and Mrp2 (show ABCC2 Antibodies) are downregulated in rodent models of necrotizing enterocolitis

  5. Large variations in hepatic bile salt flux have minor effects on expression of murine Ntcp and Bsep (show ABCB11 Antibodies) in vivo, suggesting that these transporters are abundantly expressed and able to accommodate a wide range of 'physiological' bile salt fluxes.

  6. Conserved NTCP/Ntcp 5'-regulatory region transcription regulation differs among species and is not directly regulated by small heterodimer partner (show NR0B2 Antibodies). Bile acids may regulate NTCP/Ntcp indirectly by modulating nuclear factor regulation of gene expression.

  7. Reduced levels of HNF-1alpha (show HNF1A Antibodies), RXRalpha (show RXRA Antibodies), and RARalpha (show RARA Antibodies) in CBDL FXR (show NR1H4 Antibodies)-/- mice and reduced DNA binding in CA-fed FXR (show NR1H4 Antibodies)-/- mice, despite unchanged Ntcp levels, indicate that these factors may have a minor role in regulation of mouse Ntcp during cholestasis

  8. The C51A and C106A mutants of Slc10a2 (show SLC10A2 Antibodies) showed significantly reduced TCA uptake, while no apparent difference in TCA uptake was observed for the Slc10a1-C44A (show LYPD3 Antibodies) mutant.

  9. Ntcp and Bsep (show ABCB11 Antibodies) are regulated by age, gender, cholestyramine, and bile acid, but resistant to induction by most microsomal enzyme inducers.

  10. mouse Ntcp is regulated by HNF-4alpha (show HNF4A Antibodies) via a conserved distal cis (show CISH Antibodies)-element independently of HNF-1alpha (show HNF1A Antibodies).

Human Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 1 (SLC10A1) interaction partners

  1. For Tibetans and Uygurs, no association of the three NTCP SNPs (rs7154439, rs4646287 and rs2296651) and their haplotypes with hepatitis B virus chronicity was observed.

  2. the present study indicated that the common variants in the regulatory elements of NTCP may not influence the expression level of SLC10A1 at transcriptional regulation, and ultimately may not be associated with HBV susceptibility.

  3. The data showed that S267F of sodium taurocholate cotransporting polypeptide is not associated with hepatitis B virus infection, and is not prevalent in the general Moroccan population.

  4. The SLC10A1 (NTCP) S267F variant is independently associated with decreased risk of progression to Liver cirrhosis and Hepatocellular Carcinoma , and resistance to Chronic Hepatitis B infection.

  5. In conclusion, NTCP appeared inefficient to mediate infection by serum-derived hepatitis B virus.

  6. Computer screening of NTCP inhibitors and non-inhibitors showed no relationship between the drugs and drug induced liver injury.

  7. We found a genetic variant (rs4646287) located in intron 1 of NTCP that may be associated with increased risk of HBV infection in Han Chinese

  8. The observation that the pharmacological inhibitors of the NTCP transporter could block HBV entry suggests that NTCP represents an attractive molecular target for therapeutic intervention in HBV infection.

  9. Hepatitis B virus efficiently infects non-adherent hepatoma cells via NTCP, which functions as a virus receptor.

  10. This study suggests that polymorphisms in the NTCP region may be associated with the natural course of HBV infection.

SLC10A1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids\; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.

Gene names and symbols associated with SLC10A1

  • solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (Slc10a1) antibody
  • solute carrier family 10 (sodium/bile acid cotransporter), member 1 (SLC10A1) antibody
  • solute carrier family 10 (sodium/bile acid cotransporter), member 1 (Slc10a1) antibody
  • NTCP antibody
  • Ntcp1 antibody
  • SBACT antibody

Protein level used designations for SLC10A1

Na(+)/bile acid cotransporter , Na(+)/taurocholate transport protein , bile acid cotransporting polypeptide , sodium bile acid cotransporting polypeptide , sodium-taurocholate cotransporting polypeptide , sodium/bile acid cotransporter , sodium/taurocholate cotransporting polypeptide , Na/taurocholate cotransporting polypeptide , cell growth-inhibiting gene 29 protein , growth-inhibiting protein 29 , sodium/taurocholate cotransporter , solute carrier family 10 (sodium/bile acid cotransporter family), member 1 , solute carrier family 10 member 1 , NA-dependent cholate transporting protein , sodium-dependent bile acid cotransporter , sodium-dependent taurocholate cotransporting polypeptide , solute carrier family 10, member 1

GENE ID SPECIES
20493 Mus musculus
6554 Homo sapiens
24777 Rattus norvegicus
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