You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8) Antibodies

SLC22A8 encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. Additionally we are shipping Solute Carrier Family 22 (Organic Anion Transporter), Member 8 Proteins (4) and Solute Carrier Family 22 (Organic Anion Transporter), Member 8 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC22A8 9376 Q8TCC7
SLC22A8 83500 Q9R1U7
SLC22A8 19879 O88909
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Solute Carrier Family 22 (Organic Anion Transporter), Member 8 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti OAT-3 Polyclonal Antibody, Unconjugated (ABIN670821) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using OCT3 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using OCT3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IP, WB Western blot analysis of OCT3 expression in HT29 (A), JAR (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC, ELISA, WB OAT-3 staining in stomach cancer tissue: Paraffin-embedded stomach cancer tissue is stained with OAT-3 Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$385.00
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SLC22A8 is 0.3 ng/ml as a capture antibody. SLC22A8 monoclonal antibody (M02), clone 3C11. Western Blot analysis of SLC22A8 expression in rat muscle. 100 μg Log in to see 9 Days
$430.00
Details

SLC22A8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
,
,
, , , , , , , , , , ,
Rat (Rattus) ,


Mouse (Murine) ,


Top referenced anti-Solute Carrier Family 22 (Organic Anion Transporter), Member 8 Antibodies

  1. Cow (Bovine) Polyclonal SLC22A8 Primary Antibody for WB - ABIN2776870 : Windass, Lowes, Wang, Brown: The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin. in The Journal of pharmacology and experimental therapeutics 2007 (PubMed)

  2. Human Polyclonal SLC22A8 Primary Antibody for IF (p), IHC (p) - ABIN670821 : Zhou, Yu, Zhang, Liu, Lu: Total saponins from Discorea nipponica ameliorate urate excretion in hyperuricemic mice. in Planta medica 2014 (PubMed)

More Antibodies against Solute Carrier Family 22 (Organic Anion Transporter), Member 8 Interaction Partners

Human Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8) interaction partners

  1. The putative promoter sequences from hOAT1 (SLC22A6 (show SLC22A6 Antibodies)) and hOAT3 (SCL22A8) were cloned into a reporter plasmid.

  2. Findings suggest specific involvement of each organic cation transporters (OCT1 (show POU2F1 Antibodies)-3) in drug transportation.

  3. Findings suggest that OCT3 (show POU5F1 Antibodies) plays an important role in the absorption and elimination of metformin and that the transporter is a critical determinant of metformin bioavailability, clearance, and pharmacologic action.

  4. The markers of EMT (show ITK Antibodies) were detected by using Western blot.

  5. PPIs inhibit [(3)H]MTX (show MTX1 Antibodies) transport via hOAT3 inhibition.

  6. Findings suggest a negative feedback mechanism against inflammatory response by which solute carrier family 22 member 3 (SLC22A3 (show OCT3 Antibodies)) variant rs3088442 G-->A decreased the risk of coronary heart disease (CHD (show CHDH Antibodies)).

  7. The high efficacy of bendamustine in treating chronic lymphocytic leukemia might be partly due to the expression of OAT3 in lymphoma cells and the high affinity of bendamustine for this transporter.

  8. Pemetrexed is a superior substrate to methotrexate for hOAT3.

  9. Cultured astroctye line 1321N1 and primary human astrocytes transport monoamines partly through OCT3 (show POU5F1 Antibodies).

  10. In HEK293-Flp (show HPD Antibodies)-In cells, the OAT3-Ile305Phe variant had a lower maximum cefotaxime transport activity, Vmax , [159 +/- 3 nmol*(mg protein)(-1) /min (mean +/- SD)] compared with the reference OAT3 [305 +/- 28 nmol*(mg protein)(-1) /min, (mean +/- SD), p < 0.01].

Mouse (Murine) Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8) interaction partners

  1. Arsenic and mercury containing traditional Chinese medicine (Realgar and Cinnabar) probably induce kidney damage through inhibiting several members of the organic anion transporters (such as OAT1 (show SLC22A6 Antibodies) and OAT3).

  2. Study showed that few, if any, 5-HT (show DDC Antibodies) neurons in the dorsal raphe are resistant to loss of Pet-1 (show FEV Antibodies) for expression of Slc22a3 (show OCT3 Antibodies)

  3. Findings suggest that OCT3 (show POU5F1 Antibodies) plays an important role in the absorption and elimination of metformin and that the transporter is a critical determinant of metformin bioavailability, clearance, and pharmacologic action.

  4. These results demonstrate that OCT3 (show POU5F1 Antibodies) is responsible for metformin accumulation and secretion in salivary glands.

  5. Specifically blocking its transport through OAT3 or antioxidant treatment could prevent CMPF-induced beta cell dysfunction.

  6. Oat3 also plays a role in bioenergetic pathways.

  7. At the protein level, mOat3 and mOat1 (show SLC22A6 Antibodies) exhibit sex-dependent expression with an opposite pattern; mOat3 is female dominant due to androgen inhibition, while mOat1 (show SLC22A6 Antibodies) is male dominant due to androgen stimulation.

  8. Data indicate that the expression of the organic cation transporters Slc22a1 (show SLC22A1 Antibodies), Slc22a2 (show SLC22A2 Antibodies) and Slc22a3 (show OCT3 Antibodies) essential for the cellular uptake of metformin was highly suppressed in Tsc1 (show TSC1 Antibodies)+/-renal tumours.

  9. Transcripts encoding OCT1-3 and ChAT (choline acetyltransferase) have been detected in tracheal epithelial cells; these data suggest that cells lining the airway are able to synthesize/secrete acetylcholine into the lumen.

  10. The results are consistent with a contribution of OAT3 and possibly OAT1 (show SLC22A6 Antibodies) to renal creatinine secretion in mice.

Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8) Antigen Profile

Protein Summary

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.

Gene names and symbols associated with SLC22A8

  • solute carrier family 22 (organic anion transporter), member 8 (SLC22A8) antibody
  • solute carrier family 22 (organic anion transporter), member 8 (Slc22a8) antibody
  • solute carrier family 22 (organic cation transporter), member 3 (SLC22A3) antibody
  • solute carrier family 22 (organic cation transporter), member 3 (Slc22a3) antibody
  • EMT antibody
  • EMTH antibody
  • Oat3 antibody
  • Oct3 antibody
  • Orct3 antibody
  • Roct antibody
  • Slca22a3 antibody

Protein level used designations for SLC22A8

solute carrier family 22 member 8 , organic anion transporter 3 , hOAT3 , rOat3 , solute carrier family 22 ,member 8 , rbOAT3 , renal organic anion transporter 3 , reduced in osteosclerosis transporter , solute carrier family 22, member 8 , pOAT3 , EMT organic cation transporter 3 , extraneuronal monoamine transporter , organic cation transporter 3 , solute carrier family 22 (extraneuronal monoamine transporter), member 3 , solute carrier family 22 member 3 , solute carrier family 22, member 3

GENE ID SPECIES
451274 Pan troglodytes
100172896 Pongo abelii
9376 Homo sapiens
83500 Rattus norvegicus
476049 Canis lupus familiaris
404128 Bos taurus
100008845 Oryctolagus cuniculus
19879 Mus musculus
407774 Sus scrofa
6581 Homo sapiens
20519 Mus musculus
Selected quality suppliers for anti-Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8) Antibodies
Did you look for something else?