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SLC25A46 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008].. Additionally we are shipping SLC25A46 Proteins (3) and many more products for this protein.
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Dog (Canine) Polyclonal SLC25A46 Primary Antibody for WB - ABIN2781714
Haitina, Lindblom, Renström, Fredriksson: Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. in Genomics 2006
Cow (Bovine) Polyclonal SLC25A46 Primary Antibody for WB - ABIN2773838
Nishisho, Nakamura, Miyoshi, Miki, Ando, Horii, Koyama, Utsunomiya, Baba, Hedge: Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. in Science (New York, N.Y.) 1991
recently, the "Turning calves syndrome", a novel sensorimotor polyneuropathy was described in the French Rouge-des-Pres cattle breed. In the present study, we determined that this hereditary disease resulted from a single nucleotide substitution in SLC25A46, a gene encoding a protein of the mitochondrial carrier family. This mutation caused an apparent damaging amino-acid substitution.
we showed that the Slc25a46 disruption caused a fusion/fission imbalance and an abnormal mitochondrial architecture that disturbed mitochondrial metabolism. These data extended the range of phenotypes associated with Slc25a46 dysfunction. Moreover, this Slc25a46 knock-out mouse model should be useful to further elucidate the role of SLC25A46 in mitochondrial dynamics
Our mutant mice provide a valid model for understanding the mechanistic basis of the complex SLC25A46-mediated pathologies, as well as for screening potential therapeutic interventions.
Data indicate four families with recessive mutations in solute carrier family 25 member 46 protein (SLC25A46).
Compares and contrasts all the known human SLC25A (show SLC25A25 Antibodies)* genes and includes functional information.
SLC25A46 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006
solute carrier family 25, member 46
, solute carrier family 25 member 46-like
, solute carrier family 25 member 46
, solute carrier family 25 member 46-B