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Solute Carrier Family 26, Member 5 (Prestin) Proteins (SLC26A5)

SLC26A5 encodes a member of the SLC26A/SulP transporter family. Additionally we are shipping Solute Carrier Family 26, Member 5 (Prestin) Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC26A5 375611 P58743
Rat SLC26A5 SLC26A5 83819 Q9EPH0
SLC26A5 80979 Q99NH7
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Top Solute Carrier Family 26, Member 5 (Prestin) Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

SLC26A5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5) Interaction Partners

Zebrafish Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5) interaction partners

  1. Motor function is an innovation of therian prestin and is concurrent with diminished transporter capabilities.

  2. Compared with mammalian prestin, charge movements mediated by zprestin display a weaker voltage dependence and slower kinetics; they occur at more positive membrane voltages, and are not associated with electromotile responses.

  3. sequence conservation between mammalian and nonmammalian prestin together with a common pharmacology of electromotility and divalent antiport

Human Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5) interaction partners

  1. I hypothesize that serum assays of OHC specific protein, prestin, will allow detection and quantification of OHC damage before audiometric testing can identify presence of hearing loss.

  2. anion-pi interaction is the mechanism for the voltage-dependent response of prestin

  3. The findings suggest that CASK (show CASK Proteins) and the truncated prestin splice isoform contribute to confinement of prestin to the basolateral region of the plasma membrane.

  4. The effects of fast temperature jumps induced by an infrared (IR) laser in control and prestin (SLC26a5)-transfected human embryonic kidney (HEK (show EPHA3 Proteins)) cells, are reproted.

  5. Calmodulin (show CALM1 Proteins)-prestin interaction may be involved in the medial olivocochlear-mediated modulation of cochlear amplification

  6. COCH (show COCH Proteins) and SLC26A5 mRNA are expressed in specific structures and cells of the inner ear in archival human temporal bone

  7. prestin subunits are individually functional within a given multimer

  8. This result implies that in cell membranes prestin oligomerizes to a tetramer.

  9. Four mutations (C124A, C192A, C260A, and C415A), all in nonconserved cysteinyl residues, significantly differed in their nonlinear capacitance properties compared with wild-type prestin.

  10. Cysteine mutagenesis reveals transmembrane residues associated with charge translocation in prestin

Mouse (Murine) Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5) interaction partners

  1. Prestin missense mutations reduce outer hair cell survival in knockin mice.

  2. demonstrate that OHC lateral wall structure constrains the mobility of plasma membrane proteins and that the integrity of such membrane-associated structures are critical for Slc26a5's active and structural roles

  3. SPAG6 (show SPAG6 Proteins) is indispensible for the stability of outer hair cells by maintaining the normal expression of prestin

  4. prestin is up-regulated by 32-58% in residual outer hair cell after noise exposure and that the prestin is functional.

  5. The findings suggest that CASK (show CASK Proteins) and the truncated prestin splice isoform contribute to confinement of prestin to the basolateral region of the plasma membrane.

  6. calmodulin (show Calm2 Proteins)-prestin interaction may be involved in the medial olivocochlear-mediated modulation of cochlear amplification

  7. prestin subunits are individually functional within a given multimer

  8. Prestin has a role in harnessing the basilar membrane as the source of cochlear frequency tuning.

  9. prestin knockout mice had increased auditory threshold but no changes in spine density or morphological characteristics on apical dendrites of auditory cortical layer 5 pyramidal neurons.

  10. A previously unexpected role of prestin, in mediating antibiotic-induced apoptosis, the effect of which is associated with its anion-transporting capacity.

Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5) Protein Profile

Protein Summary

This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC26A5

  • solute carrier family 26, member 5 (slc26a5)
  • solute carrier family 26, member 5 (prestin) (SLC26A5)
  • solute carrier family 26, member 5 (prestin) (slc26a5)
  • solute carrier family 26 (anion exchanger), member 5 (SLC26A5)
  • solute carrier family 26 (anion exchanger), member 5 (Slc26a5)
  • solute carrier family 26, member 5 (Slc26a5)
  • DFNB61 protein
  • fb73d12 protein
  • fb74g12 protein
  • Pres protein
  • prestin protein
  • wu:fb73d12 protein
  • wu:fb74g12 protein

Protein level used designations for SLC26A5

prestin , zprestin , solute carrier family 26, member 5 (prestin) , prestin-like , prestin (motor protein) , solute carrier family 26 member 5 , outer hair cell motor protein , solute carrier family 26, member 5 (prestin) isoform 1 , solute carrier family 26, member 5 (prestin) isoform 2

GENE ID SPECIES
322846 Danio rerio
417715 Gallus gallus
696074 Macaca mulatta
742668 Pan troglodytes
100017934 Monodelphis domestica
100076611 Ornithorhynchus anatinus
100190993 Sus scrofa
100192303 Felis catus
100216333 Oryctolagus cuniculus
100404551 Callithrix jacchus
100479701 Ailuropoda melanoleuca
100497573 Xenopus (Silurana) tropicalis
100594832 Nomascus leucogenys
375611 Homo sapiens
83819 Rattus norvegicus
80979 Mus musculus
483274 Canis lupus familiaris
536341 Bos taurus
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