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SLC29A4 is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. Additionally we are shipping Solute Carrier Family 29 (Nucleoside Transporters), Member 4 Proteins (3) and many more products for this protein.
Showing 10 out of 83 products:
Human Polyclonal SLC29A4 Primary Antibody for EIA, IHC (p) - ABIN356636
Barnes, Dobrzynski, Foppolo, Beal, Ismat, Scullion, Sun, Tellez, Ritzel, Claycomb, Cass, Young, Billeter-Clark, Boyett, Baldwin: Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH. in Circulation research 2006
Show all 2 references for ABIN356636
Human Polyclonal SLC29A4 Primary Antibody for EIA, WB - ABIN356637
Engel, Zhou, Wang: Identification and characterization of a novel monoamine transporter in the human brain. in The Journal of biological chemistry 2004
Show all 2 references for ABIN356637
Cultured astroctye line 1321N1 and primary human astrocytes transport monoamines predominantly through PMAT.
Transport kinetic analysis revealed that I89M mutant in PMAT protein had a 2.7-fold reduction in maximal transport velocity with no significant change in apparent binding affinity.
Data show that ENT1 (show SLC29A1 Antibodies), ENT2 (show SLC29A2 Antibodies), ENT4 and CNT3 (show SLC28A3 Antibodies) protein was detected on ovarian carcinoma cells in all effusions, with expression observed in 1-95% of tumor cells.
The selectivity and kinetics of monoamine neurotransmitter transport by PMAT and OCT3 (show POU5F1 Antibodies) was determined. PMAT is expressed at much higher levels than hOCT3 in brain, whereas hOCT3 is selectively and highly expressed in adrenal gland and skeletal muscle.
PMAT can function as a polyspecific organic cation transporter, which may play a role in organic cation transport in vivo.
ENT4, in addition to playing roles in cardiac serotonin transport, contributes to the regulation of extracellular adenosine concentrations, in particular under the acidotic conditions associated with ischemia.
our data suggest that PMAT is expressed on the apical membranes of renal epithelial cells and may use luminal proton gradient to drive organic cation reabsorption in the kidney.
PMAT, EMT (show ITK Antibodies), and OCT2 transporters are expressed in the endometrial stroma and can potentially regulate reuptake of monoamines in general and histamine in particular.
identification of ENT4 as a highly expressed transcript in desmoplastic small round cell tumor (DSRCT) may represent an attractive pathway for targeting chemotherapeutic drugs into DSRCT
The data suggest that PMAT is specifically expressed in podocytes and may play an important role in puromycin aminonucleoside-induced kidney injury.
PMAT is a major transporter for choroid plexus uptake of bioactive amines and xenobiotic cations.
This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized.
equilibrative nucleoside transporter 4
, solute carrier family 29 member 4
, solute carrier family 29 (nucleoside transporters), member 4
, plasma membrane monoamine transporter